HALO® HPLC Columns for Biopharma Separations
Advancing the understanding of form and function for biomolecules, researchers supporting their development and release employ many orthogonal techniques and separation methodologies to develop a more complete therapeutic picture.
With both tailored particle and pore size options, HALO® BIOCLASS offers application-specific solutions for:
- Intact proteins, monoclonal antibodies (mAbs), biosimilars, and other large biomolecules such as pegylated proteins, antibody-drug conjugates (ADCs), etc.
- Peptide mapping (analysis of enzyme digests) for characterization and monitoring of synthetic protein drugs
- Analysis of therapeutic peptides and peptide biomarkers (protein surrogates)
- High-resolution separations of complex mixtures of glycans released from N- and O-linked glycoproteins
PROTEIN SEPARATIONS
HALO® 1000 A Diphenyl
HALO; Fused-Core; HPLC; columns; UHPLC; AMT; Diphenyl; Bioclass; Protein; Peptide; Glycan; reversed phase; core-shell; solid-core; 1000A column; 1000 A; mAb column; USP L11; large molecule
HALO® 1000 A C4
HALO; Fused-Core; HPLC; columns; UHPLC; AMT; C4; Bioclass; Protein; Peptide; Glycan; reversed phase; core-shell; solid-core; 1000A column; 1000 A; mAb column; USP L26; large molecule
HALO® 1000 A ES-C18
HALO; Fused-Core; HPLC; columns; UHPLC; AMT; C18; ES-C18; Bioclass; Protein; Peptide; Glycan; reversed phase; core-shell; solid-core; 1000A column; 1000 A; mAb column; USP L1; large molecule
HALO® 400 A Diphenyl
HALO; Fused-Core; HPLC; columns; UHPLC; AMT; Diphenyl; Bioclass; Protein; Peptide; Glycan; reversed phase; core-shell; solid-core; 400A column; 400 A; mAb column; USP L11; large molecule
HALO® 400 A C4
HALO; Fused-Core; HPLC; columns; UHPLC; AMT; C4; Bioclass; Protein; Peptide; Glycan; reversed phase; core-shell; solid-core; 400A column; 400 A; mAb column; USP L26; large molecule
HALO® 400 A ES-C18
HALO; Fused-Core; HPLC; columns; UHPLC; AMT; C18; ES-C18; Bioclass; Protein; Peptide; Glycan; reversed phase; core-shell; solid-core; 400A column; 400 A; mAb column; USP L1; large molecule
HALO® 160 A ES-C18
HALO; Fused-Core; HPLC; columns; UHPLC; AMT; ES-C18; C18; Bioclass; Protein; Peptide; Glycan; reversed phase; core-shell; solid-core; 160A column; 160 A; peptide column; USP L1
HALO® 160 A ES-CN
HALO; Fused-Core; HPLC; columns; UHPLC; AMT; ES-CN; cyano; Bioclass; Protein; Peptide; Glycan; reversed phase; core-shell; solid-core; 160A column; 160 A; peptide column; USP L10
HALO® 160 A Phenyl-Hexyl
HALO; Fused-Core; HPLC; columns; UHPLC; AMT; Phenyl Hexyl; Bioclass; Protein; Peptide; Glycan; reversed phase; core-shell; solid-core; 160A column; 160 A; peptide column; USP L11
HALO® 90 A Glycan
HALO; Fused-Core; HPLC; columns; UHPLC; AMT; Bioclass; Protein; Peptide; Glycan; core-shell; solid-core; 90A column; 90 A; glycan column; USP L95