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Catalog Number: (10068-970)
Supplier: Prosci
Description: Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level


Catalog Number: (89288-520)
Supplier: Genetex
Description: Rabbit polyclonal antibody to SHMT2 (N-terminal)


Catalog Number: (89270-386)
Supplier: Genetex
Description: Rabbit polyclonal antibody to FUSIP1 (C-terminal)


Catalog Number: (10457-362)
Supplier: Bioss
Description: STK40 may be a negative regulator of NF-kappa-B and p53-mediated gene transcription. There are four named isoforms.


Catalog Number: (10068-716)
Supplier: Prosci
Description: Inhibits the activity of dimeric NF-κ-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.


Catalog Number: (89270-118)
Supplier: Genetex
Description: Rabbit polyclonal antibody to PRSS16 (Middle)


Catalog Number: (10111-088)
Supplier: Prosci
Description: Serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)


Catalog Number: (89295-626)
Supplier: Genetex
Description: Sheep Polyclonal antibody to Protease Nexin 1 (HRP)


Catalog Number: (89271-890)
Supplier: Genetex
Description: Mouse monoclonal antibody [3C12] to STK39


Catalog Number: (89295-744)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to antithrombin III (Biotin)


Catalog Number: (10068-968)
Supplier: Prosci
Description: Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.


Catalog Number: (10814-074)
Supplier: Prosci
Description: Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2). The phosphorylated form of RAF1 (on residues Ser-338 and Ser-339, by PAK1) phosphorylates BAD/Bcl2-antagonist of cell death at 'Ser-75'. Phosphorylates adenylyl cyclases: ADCY2, ADCY5 and ADCY6, resulting in their activation. Phosphorylates PPP1R12A resulting in inhibition of the phosphatase activity. Phosphorylates TNNT2/cardiac muscle troponin T. Can promote NF-kB activation and inhibit signal transducers involved in motility (ROCK2), apoptosis (MAP3K5/ASK1 and STK3/MST2), proliferation and angiogenesis (RB1). Can protect cells from apoptosis also by translocating to the mitochondria where it binds BCL2 and displaces BAD/Bcl2-antagonist of cell death. Regulates Rho signaling and migration, and is required for normal wound healing. Plays a role in the oncogenic transformation of epithelial cells via repression of the TJ protein, occludin (OCLN) by inducing the up-regulation of a transcriptional repressor SNAI2/SLUG, which induces down-regulation of OCLN. Restricts caspase activation in response to selected stimuli, notably Fas stimulation, pathogen-mediated macrophage apoptosis, and erythroid differentiation.


Catalog Number: (10476-068)
Supplier: Bioss
Description: SRRM3


Catalog Number: (103010-118)
Supplier: Anaspec Inc
Description: p-Nitrophenyl phosphate (pNPP) is proven to be an effective chromogenic substrate for protein tyrosine phosphatases and serine/threonine phosphatases


Catalog Number: (10094-142)
Supplier: Proteintech
Description: SARS(Serine--tRNA ligase, cytoplasmic) Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).The deduced 514-amino acid protein has a calculated molecular mass of about 59 kD.And it can form a dimer of 120KDa.It is detected a band of 65KDa in MEL cell lines.


Catalog Number: (89295-630)
Supplier: Genetex
Description: Sheep Polyclonal antibody to Protease Nexin 1 (Biotin)


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