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Anti-IL-2 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: JES6-5H4]

Description: The JES6-5H4 antibody specifically binds to mouse IL-2, a 17 kDa immunoregulatory cytokine and growth factor for T and B lymphocytes, NK cells, monocytes, and macrophages. IL-2 induces the cytotoxic operations of NK cells, activates B cells, and plays a role in the differentiation of T cells. JES6-5H4 seems to have a neutralizing effect on interleukin-2.
Catalog Number: 75841-464
Supplier: BIOGEMS INTERNATIONAL INC.
Image Unavailable-75841-446

Anti-MHC Class II Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: M5/114.15.2]

Description: The M5/114.15.2 monoclonal antibody or (M5/114) is specific for the mouse major histocompatibility complex class II, specific for the I-A and I-E subregion-encoded glycoproteins (alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, but not the I-Af, I-Ak, nor I-As antigens). The antibody also reacts with cells from the H-2p or H-2r haplotypes mice. The polymorphic determinant represented by the mouse major histocompatibility complex class II (MHC Class II) is expressed by the immune cells bearing the specified alloantigens, like T and B lymphocytes, monocytes, dendritic cells, and macrophages. The antibody doesn’t react with the NOD H-2g7 haplotype alloantigens. M5/114 mAb inhibits I-A-restricted T cell responses of the Haplotypes H-2b, H-2d, H-2q, and H-2u.
Catalog Number: 75841-446
Supplier: BIOGEMS INTERNATIONAL INC.
Image Unavailable-75841-460

Anti-IL-2 (JES6-5H4) Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: JES6-5H4]

Description: The JES6-5H4 antibody specifically binds to mouse IL-2, a 17 kDa immunoregulatory cytokine and growth factor for T and B lymphocytes, NK cells, monocytes, and macrophages. IL-2 induces the cytotoxic operations of NK cells, activates B cells, and plays a role in the differentiation of T cells. JES6-5H4 seems to have a neutralizing effect on interleukin-2.
Catalog Number: 75841-460
Supplier: BIOGEMS INTERNATIONAL INC.
Image Unavailable-75841-494

Anti-CD1d Rat Monoclonal Antibody [clone: 1B1]

Description: The 1B1 monoclonal antibody specifically reacts with mouse CD1d, a 48kDA type I membrane glycoprotein with a structural homology to MHC class I molecules. CD1d is expressed by mouse leukocytes, epithelial cells, thymocytes, and dendritic cells and is the only molecules in the CD1 family to have been found in the mouse. The 1B1 antibody detects CD1d in association with the Beta2m molecule.
Catalog Number: 75841-494
Supplier: BIOGEMS INTERNATIONAL INC.
Image Unavailable-75841-540

Anti-CD11c Armenian Hamster Monoclonal Antibody (PerCP (Peridinin-Chlorophyll Protein Complex)-Cy5.5®) [clone: N418]

Description: The N418 monoclonal antibody specifically reacts with the integrin αx chain of the mouse CD11c, which is expressed on dendritic cells, CD4-/CD8+ intestinal intraepithelial lymphocytes (IEL) and some activated T lymphocytes. Low levels of CD11c were detected on mouse splenic natural killer cells and on the monocyte/macrophage lineage cells.CD11c expression is upregulated on IEL and T lymphocytes after activation. It binds to CD54, fibrinogen and iC3b and influences the leukocyte adhesive interactions. The N418 antibody binds to CD11c on splenic dendritic cells of the mouse in the T-dependent areas. It also contributes to the binding of iC3b.
Catalog Number: 75841-540
Supplier: BIOGEMS INTERNATIONAL INC.
Image Unavailable-75841-544

Anti-CD11c Armenian Hamster Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: N418]

Description: The N418 monoclonal antibody specifically reacts with the integrin αx chain of the mouse CD11c, which is expressed on dendritic cells, CD4-/CD8+ intestinal intraepithelial lymphocytes (IEL) and some activated T lymphocytes. Low levels of CD11c were detected on mouse splenic natural killer cells and on the monocyte/macrophage lineage cells.CD11c expression is upregulated on IEL and T lymphocytes after activation. It binds to CD54, fibrinogen and iC3b and influences the leukocyte adhesive interactions. The N418 antibody binds to CD11c on splenic dendritic cells of the mouse in the T-dependent areas. It also contributes to the binding of iC3b.
Catalog Number: 75841-544
Supplier: BIOGEMS INTERNATIONAL INC.
Image Unavailable-75841-534

Anti-CD11c Armenian Hamster Monoclonal Antibody (PE (Phycoerythrin)) [clone: N418]

Description: The N418 monoclonal antibody specifically reacts with the integrin αx chain of the mouse CD11c, which is expressed on dendritic cells, CD4-/CD8+ intestinal intraepithelial lymphocytes (IEL) and some activated T lymphocytes. Low levels of CD11c were detected on mouse splenic natural killer cells and on the monocyte/macrophage lineage cells.CD11c expression is upregulated on IEL and T lymphocytes after activation. It binds to CD54, fibrinogen and iC3b and influences the leukocyte adhesive interactions. The N418 antibody binds to CD11c on splenic dendritic cells of the mouse in the T-dependent areas. It also contributes to the binding of iC3b.
Catalog Number: 75841-534
Supplier: BIOGEMS INTERNATIONAL INC.
Image Unavailable-75841-504

Anti-CD11b Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: ICRF44]

Description: The ICRF44 monoclonal antibody specifically reacts with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin β2) a complex known as Mac-1. CD11b is expressed on the surface of activated lymphocytes, a subset of natural killer cells, granulocytes, and monocytes. It functions as a receptor in cell-cell and cell-matrix interactions and as a receptor for iC3b, ICAM-1, ICAM-2, and ICAM-3 intercellular adhesion molecules.
Catalog Number: 75841-504
Supplier: BIOGEMS INTERNATIONAL INC.
Image Unavailable-75841-502

Anti-CD11b Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: ICRF44]

Description: The ICRF44 monoclonal antibody specifically reacts with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin β2) a complex known as Mac-1. CD11b is expressed on the surface of activated lymphocytes, a subset of natural killer cells, granulocytes, and monocytes. It functions as a receptor in cell-cell and cell-matrix interactions and as a receptor for iC3b, ICAM-1, ICAM-2, and ICAM-3 intercellular adhesion molecules.
Catalog Number: 75841-502
Supplier: BIOGEMS INTERNATIONAL INC.
Image Unavailable-75841-508

Anti-CD11b (ICRF44) Mouse Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: ICRF44]

Description: The ICRF44 monoclonal antibody specifically reacts with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin β2) a complex known as Mac-1. CD11b is expressed on the surface of activated lymphocytes, a subset of natural killer cells, granulocytes, and monocytes. It functions as a receptor in cell-cell and cell-matrix interactions and as a receptor for iC3b, ICAM-1, ICAM-2, and ICAM-3 intercellular adhesion molecules.
Catalog Number: 75841-508
Supplier: BIOGEMS INTERNATIONAL INC.
Image Unavailable-75841-558

Anti-CD11b Rat Monoclonal Antibody [clone: M1/70]

Description: The M1/70 monoclonal antibody specifically reacts with the 170 kDa αM integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18). Mac-1 binds to C3bi, CD54 (ICAM-1), and fibrinogen, and it is expressed by granulocytes, macrophages, NK cells, myeloid-derived dendritic cells, microglia, activated lymphocytes, and mouse B-1 cells. The expression is up-regulated on activated neutrophils at the same time that L-selectin is shed from the cell surface. The M1/70 antibody is used for the detection of monocytes, granulocytes, and a subset of natural killer cells in human peripheral blood.M1/70 blocks C3bi binding and cell adherence, but not cell-mediated lysis and it cross-reacts with human CD11b.
Catalog Number: 75841-558
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CD3e Armenian Hamster Monoclonal Antibody [clone: 145-2C11]

Description: The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex. Together with the γ and δ subunits of CD3, the ε subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the ε chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.
Catalog Number: 75841-720
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CD14 Mouse Monoclonal Antibody (PerCP (Peridinin-Chlorophyll Protein Complex)-Cy5.5®) [clone: 61D3]

Description: The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
Catalog Number: 75841-756
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CD3 Mouse Monoclonal Antibody [clone: OKT3]

Description: The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.
Catalog Number: 75841-708
Supplier: BIOGEMS INTERNATIONAL INC.
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Anti-CD3 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: G4.18]

Description: The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.
Catalog Number: 75841-700
Supplier: BIOGEMS INTERNATIONAL INC.
Image Unavailable-75841-746

Anti-CD14 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 61D3]

Description: The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
Catalog Number: 75841-746
Supplier: BIOGEMS INTERNATIONAL INC.
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