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Catalog Number: (77126-940)
Supplier: Prosci
Description: EPHB4 Peptide


Catalog Number: (89419-604)
Supplier: Prosci
Description: ATG12 peptide is used for blocking the activity of ATG12 antibody.


Catalog Number: (77122-188)
Supplier: Prosci
Description: AIP Peptide


Catalog Number: (75793-660)
Supplier: Prosci
Description: The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.


Catalog Number: (89421-036)
Supplier: Prosci
Description: SPRYD2 peptide is used for blocking the activity of SPRYD2 antibody.


Catalog Number: (75791-794)
Supplier: Prosci
Description: Serpin B3 is a protein that in humans is encoded by the SERPINB3 gene, belongs to the serpin family, Ov-serpin subfamily, May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).


Catalog Number: (75793-920)
Supplier: Prosci
Description: IL-37 (IL-1F7; IL-1H4) belongs to the IL-1 family of proteins. It binds to the interleukin-18 receptor (IL-18R) but not to the IL-1 receptor. It plays an important role as a link between innate and adaptive immunity. IL-37 is a new player in inflammatory and immune responses, mediated by the IL-18/IL-18R axis. It was shown to inhibit tumor growth.


Catalog Number: (89419-074)
Supplier: Prosci
Description: Bit1 peptide is used for blocking the activity of Bit1 antibody.


Catalog Number: (75793-692)
Supplier: Prosci
Description: Lipocalin-2 is an iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development.


Catalog Number: (89421-094)
Supplier: Prosci
Description: HIG1 peptide is used for blocking the activity of HIG1 antibody.


Catalog Number: (77123-346)
Supplier: Prosci
Description: FGF22 Peptide


Catalog Number: (89420-674)
Supplier: Prosci
Description: SCRN1 peptide is used for blocking the activity of SCRN1 antibody.


Catalog Number: (75793-972)
Supplier: Prosci
Description: BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases such as Sjoegren syndrome, Rheumatoid arthritis (RA), Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE). BAFF has also increased levels in some lymphoid cancers.


Catalog Number: (10797-502)
Supplier: Prosci
Description: Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.


Catalog Number: (75791-188)
Supplier: Prosci
Description: neuregulin-1 (heregulin-1,NRG1) is a member of neuregulin family, which is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. NRG1 isoforms can be classified into type I, type II and type III isoforms. NRG1 directs ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.


Catalog Number: (77133-824)
Supplier: Prosci
Description: Dvl1 Peptide


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