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Catalog Number: (89147-664)
Supplier: Enzo Life Sciences
Description: Represents a class of natural compounds, which inhibit proliferation in eukaryotes by blocking nuclear export. As potent as leptomycin B (Prod. No. ALX-380-100) and specific for G1/S checkpoint. Cytotoxic secondary metabolite (IC50=50pg/ml in mouse cell line L929) that arrests tumor cells in the G1 phase at remarkably low concentrations (50pg/ml in HeLa cell line KB3.1). Inhibits the binding between the nuclear export signal (NES) of proteins and the chromosome maintenance region protein (CRM1). Anticancer compound. Belongs to the family of orphan ligands which include polyketides like leptomycin B, callystatin A and other related compounds.


Supplier: Enzo Life Sciences
Description: Cathepsin substrate

Supplier: Enzo Life Sciences
Description: A competitive, reversible inhibitor of serine proteases tryptase (Ki=3.4nM), thrombin (Ki=500nM), uPA (Ki=1.3µM), plasmin (Ki=1.5µM), trypsin (Ki=2µM), factor Xa (Ki=2µM). At higher concentrations it inhibits kallikrein-1 (Ki=2.6mM), C1 esterase (IC50=520µM), as well as phospholipase A2 (IC50=500µM), rat iNOS (Ki=5mM) and cNOS (Ki=150µM), and swine kidney copper amine oxidase (Ki=27µM), but not chymotrypsin. Has been used in tissue culture and in vivo. In clinical use for pancreatitis.

Catalog Number: (89152-968)
Supplier: Enzo Life Sciences
Description: Topoisomerase inhibitor


Catalog Number: (89156-860)
Supplier: Enzo Life Sciences
Description: ATPase inhibitor


Supplier: Enzo Life Sciences
Description: Selective activator of cGMP-dependent protein kinase (PKG) Iα, Iβ, and type II as well as of cGMP-gated ion channels.

Supplier: Enzo Life Sciences
Description: Tyrosine kinase inhibitor

Catalog Number: (89156-690)
Supplier: Enzo Life Sciences
Description: Bac5 is a 5-kDa proline-arginine rich antibiotic with a high degree of homology with PR39, an inhibitor of the 20S and 26S proteasome. Recently bactenecin 5 has been demonstrated to inhibit the chymotrypsin-like activity of the 20S proteasome.


Catalog Number: (89160-284)
Supplier: Enzo Life Sciences
Description: FLUOR DE LYS® Developer is an essential reagent for signal generation in HDAC or sirtuin assays done with the FLUOR DE LYS® substrate. An appropriate FLUOR DE LYS® family substrate, comprising an acetylated lysine side chain, is first incubated with a sample containing HDAC activity (nuclear or cellular extract, purified enzyme, bead-bound immunocomplex, etc.).


Catalog Number: (89156-500)
Supplier: Enzo Life Sciences
Description: The DPPIV Drug Discovery Kit is a complete assay system designed to screen DPPIV inhibitors, a potential therapeutic target, providing enough material to perform at least 96 assays.


Catalog Number: (89164-370)
Supplier: Enzo Life Sciences
Description: Produced in <i>E. coli</i>. Human 14-3-3ζ is fused at the C-terminus to a His-tag.


Catalog Number: (89161-208)
Supplier: Enzo Life Sciences
Description: EGFR substrate


Supplier: Enzo Life Sciences
Description: A potent and selective vanilloid receptor (TRPV1) antagonist. An effective antagonist of hTRPV1 when stimulated by capsaicin, acid, or noxious heat.

Catalog Number: (89151-772)
Supplier: Enzo Life Sciences
Description: Produced in HEK 293 cells. The cysteine-rich domain of human NGFR (nerve growth factor receptor; p75NTR) (aa 1-250) is fused to the Fc portion of human IgG1.


Catalog Number: (89144-998)
Supplier: Enzo Life Sciences
Description: Isolated from calf thymus.


Catalog Number: (89141-754)
Supplier: Enzo Life Sciences
Description: For the quantitative determination of total Nitric Oxide in culture supernatants, plasma, serum, saliva, and urine from any species


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