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Spec-Tec® Spectra® Fiber Sterile Critical Environment Glove Liners, Wells Lamont

Supplier: Wells Lamont
Description: Cut-resistant liners are ideal for pathologists, coroners, hospital waste handlers, and orthopedic, trauma, and general surgeons.

Image Unavailable-10073-034

Human Recombinant Lin28-Tat (from E. coli)

Catalog Number: (10073-034)
Supplier: Prosci
Description: Lin28 is a RNA-binding protein that belongs to a diverse family of structurally-related transcription factors. Lin28 is found abundantly in embryonic stem cells (ESCs), and to a lesser extent in placenta and testis. Lin28 has been shown to block let-7 microRNA processing and maturation, a necessary step in the differentiation of stem cells and certain cancer cell lines. Together with Sox2, Oct4, and Nanog, Lin28 can induce the reprogramming of primary human fibroblasts to a pluripotent state. Lin28 and other regulatory proteins can be introduced into cells by DNA transfection, viral infection, or microinjection. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing proteins into primary as well as transformed cells. Recombinant human Lin28-TAT is a 24.4 kDa protein containing 222 amino acid residues, including 13- residue C-terminal TAT peptide.
Product Image-76293-224

Corning® Gosselin™ Water Sampling Octagonal PET Bottles, Corning

Supplier: VWR International
Description: The Corning® Gosselin™ Water Sampling Bottle is designed to meet water sample collection requirements of the United States EPA and Health Canada. These lightweight 125 and 250 ml PET bottles are pre-dosed with 160 mg/L pentahydrated sodium thiosulfate, which provides enhanced stabilization of chlorinated water.

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Synthetic Human xCT (from HEK293 cells)

Supplier: ANTIBODIES.COM LLC
Description: Synthetic Human xCT (from HEK293 cells)

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Human Recombinant Klotho (from CHO Cells)

Catalog Number: (10072-740)
Supplier: Prosci
Description: Klotho is a glycosylated protein that plays an important role in the regulation of phosphate and calcium homeostasis. The full length transmembrane form has a large extracellular domain composed of two homologous subunits termed KL1 and KL2, which contain 516 and 439 amino acid residues, respectively, The predominant circulating form, which is derived from alternative RNA splicing, contains the KL1 subunit and constitutes the N-terminal sequence of transmembrane Klotho. A third Klotho protein of about 128 kDa has been identified in the blood and cerebrospinal fluid. This circulating protein arises from the action of an as yet unidentified protease which cleaves transmembrane Klotho just above and/or within the plasma membrane. Klotho has been shown to play a key role in the signaling cascade of fibroblast growth factor-23 (FGF-23), a bone derived hormone that acts in the kidney to inhibit phosphate reabsorption and vitamin D biosynthesis. Klotho promotes FGF-23 signaling through binding to FGFRI (IIIc) which converts this canonical FGF receptor into a specific receptor for FGF-23. In the absence of Klotho the function of FGF-23 is literally abolished. Recombinant human Klotho is a 65-70 kDa glycoprotein containing 516 amino acid residues.
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Human Recombinant SCD27 Ligand (from CHO Cells)

Catalog Number: (10073-042)
Supplier: Prosci
Description: CD27 Ligand, a type II transmembrane protein, is a member of the TNF superfamily. It is expressed on activated T and B lymphocytes as well as NK cells. CD27L and its receptor (CD27) regulate the immune response by promoting T-cell expansion and differentiation, as well as NK enhancement. CD27 signaling can act as a co-stimulatory effector to sustain the survival of CD8+ T cells, primarily by inducing increased expression of the IL-2 gene. Full length human CD27L is a 193 amino acid protein, consisting of a 17 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 155 amino acid extracellular domain. Human soluble CD27L corresponds to the 155 amino acid extracellular domain of the full length CD27L protein. ProSci’s recombinant human sCD27L contains the extracellular domain plus an N-terminal His-Tag.
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Mouse Recombinant IL17A (from E. coli)

Supplier: Prosci
Description: Human IL-17A is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant human IL-17A is a 31.0 kDa disulfide-linked homodimer of two 136 amino acid polypeptide chains.

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Human Recombinant BD4 (from E. coli)

Catalog Number: (10072-656)
Supplier: Prosci
Description: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, four human β-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. BD-4 is expressed in testis, stomach, uterus, neutrophils, thyroid, lung and kidney. In addition to its direct antimicrobial activities, BD-4 is chemoattractant towards human blood monocytes. Recombinant human BD-4 is a 6.0 kDa protein containing 50 amino acid residues.
Product Image-77676-852

Safety ECO Funnels

Supplier: CP Lab Safety
Description: ECO Funnel® is the ultimate lab safety product for collection of hazardous liquid waste. When securely attached onto an open waste container, it prevents 99.9% of toxic fumes from being released into lab. ECO Funnel is designed to prevent fires caused by ignited vapors as well as spills of hazardous waste from open containers, which helps laboratories stay compliant with local health and safety codes.

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Human Recombinant CD14 (soluble) (from HEK293 cells)

Catalog Number: (10072-746)
Supplier: Prosci
Description: CD14 is a cell surface anchored glycoprotein that is expressed predominantly by monocytes and tissue macrophages. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappa-β. CD14 also exists in a soluble form, designated as sCD14, which is capable of specifically binding LPS in the extracellular space. Recombinant sCD14 is a 331 amino acid glycoprotein comprising the extracellular portion of the CD14 receptor.
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Anti-IgG Goat Polyclonal Antibody

Catalog Number: (89307-166)
Supplier: Genetex
Description: Conjugation Pkg Size: 250 ug
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Accessories for InGel™ Silver for Protein Digestion, G-Biosciences

Catalog Number: (CA82021-382)
Supplier: G-Biosciences
Description: 100 preps. A high-diffusion peptide extraction buffer for extraction of trypsin digested peptides.
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Bis(2,4-pentanedionato)molybdenum(VI) dioxide ≥99%

Catalog Number: (CAAA44140-04)
Supplier: Thermo Scientific Chemicals
Description: Fieser: 18,244 19,222

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Anti-Buprenorphine Mouse Monoclonal Antibody [clone: B342M]

Catalog Number: (89294-568)
Supplier: Genetex
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Anti-Hepatitis C NS4 Goat Polyclonal Antibody

Catalog Number: (89363-382)
Supplier: Genetex
Description: HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural protein necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
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Anti-Benzoylecgonine Mouse Monoclonal Antibody [clone: P93]

Catalog Number: (89287-746)
Supplier: Genetex
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