You Searched For: trans-4-tert-Butylcyclohexanecarboxylic+acid


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Catalog Number: (TCB3831-5G)
Supplier: TCI America
Description: CAS Number: 35264-09-6
MDL Number: MFCD01076126
Molecular Formula: C11H19NO4
Molecular Weight: 229.28
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Melting point (°C): 133

SDS


Catalog Number: (CAPIPA5-18248)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with bovine, mouse and rat based on sequence homology. This gene belongs to a group of vacuolar protein sorting genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.


Catalog Number: (CAPI22360)
Supplier: Thermo Scientific
Description: Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

Catalog Number: (TCB4806-1G)
Supplier: TCI America
Description: 2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]hept-5-ene, Purity: >95.0%(GC), Cas no. 188345-71-3, Molecular formula: C11H17NO2, Form: Clear, Synonyms: tert-Butyl 2-Azabicyclo[2.2.1]hept-5-ene-2-carboxylate, Size: 1G

SDS


Supplier: TCI America
Description: CAS Number: 1694-31-1
MDL Number: MFCD00008811
Molecular Formula: C8H14O3
Molecular Weight: 158.20
Purity/Analysis Method: >95.0% (GC)
Form: Clear Liquid
Boiling point (°C): 184
Flash Point (°C): 66
Specific Gravity (20/20): 0.97
Supplier: Bachem Americas
Description: Sequence: Boc-3,4-dehydro-Pro-OH

Supplier: Thermo Scientific Chemicals
Description: Boc-D-Pro-OH 98+%
Catalog Number: (10423-850)
Supplier: Bioss
Description: Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.


Catalog Number: (A-3860.0005BA)
Supplier: Bachem Americas
Description: Sequence: Boc-β-chloro-Ala-OH


Catalog Number: (10087-270)
Supplier: Proteintech
Description: GOLPH3 (also called GPP34, GMx33, MIDAS, or yeast Vps74p) is a 34-kDa Golgi-associated protein conserved from yeast to human. GOLPH3 binds to PtdIns(4)P-rich trans-Golgi membranes and MYO18A conveying a tensile force required for efficient tubule and vesicle formation . GOLPH3 has been recently demonstrated as a novel oncoprotein amplified in various types of human malignancies, including melanoma, breast, non-small cell lung cancer, gliomas and connective tissue tumors . Enhanced activation of mTOR signalling represents a molecular basis for the oncogenic activity of GOLPH3 .


Supplier: Bachem Americas
Description: Sequence: Boc-Cys(Trt)-OH

Catalog Number: (89416-092)
Supplier: Prosci
Description: TIP47 Antibody: Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.


Catalog Number: (10424-254)
Supplier: Bioss
Description: Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.


Supplier: Bachem Americas
Description: Sequence: 11-(Boc-amino)-undecanoic acid

Catalog Number: (10084-638)
Supplier: Proteintech
Description: Cyclophilin A, also named as PPIA and Rotamase A, belongs to the cyclophilin-type PPIase family and PPIase A subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. PPIA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.


Catalog Number: (TCB1630-005G)
Supplier: TCI America
Description: CAS Number: 15260-10-3
MDL Number: MFCD00066062
Molecular Formula: C16H23NO5
Molecular Weight: 309.36
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 116
Specific rotation [a]20/D: 16.5 deg (C=1, MeOH)

SDS


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