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Image Unavailable-75790-188

Human Recombinant CD99 antigen-like 2 (from Cells)

Catalog Number: (75790-188)
Supplier: Prosci
Description: CD99 Antigen-Like Protein 2 (CD99L2) belongs to the CD99 family. CD99L2 is a single-pass type I membrane protein and expressed in many tissues, with low expression in thymus. CD99L2 plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants.
Product Image-10070-062

Anti-TP53 Rabbit Polyclonal Antibody

Catalog Number: (10070-062)
Supplier: Prosci
Description: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.
Product Image-CA200063-292

Anti-LAMP2 Rat Monoclonal Antibody

Supplier: Enzo Life Sciences
Description: Lysosome-associated membrane proteins (LAMP1 and LAMP2) are type I integral membrane protein that are transported from the trans-Golgi network to endosomes and then lysosomes. Following activation of platelets, T-cells, neutrophils, or endothelium, LAMP1 and LAMP2 are expressed on the cell surface. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, and loss of LAMP2 expression is associated with impaired autophagy observed in Danons disease.

Product Image-CA95046-438

Anti-LAMP1 Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences
Description: Lysosome-associated membrane proteins (LAMP1 and LAMP2) are type I integral membrane protein that are transported from the trans-Golgi network to endosomes and then lysosomes. Following activation of platelets, T-cells, neutrophils, or endothelium, LAMP1 and LAMP2 are expressed on the cell surface. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, and loss of LAMP2 expression is associated with impaired autophagy observed in Danons disease.

Image Unavailable-89297-362

Anti-PIN1 Goat Polyclonal Antibody

Catalog Number: (89297-362)
Supplier: Genetex
Description: Goat polyclonal antibody to PIN1
Image Unavailable-89266-574

Anti-PIN4 Rabbit Polyclonal Antibody

Catalog Number: (89266-574)
Supplier: Genetex
Description: Rabbit polyclonal antibody to PIN4 (Middle)
Image Unavailable-89289-620

Anti-TECR Rabbit Polyclonal Antibody

Catalog Number: (89289-620)
Supplier: Genetex
Description: Rabbit polyclonal antibody to GPSN2
Image Unavailable-89270-148

Anti-RDH16 Rabbit Polyclonal Antibody

Catalog Number: (89270-148)
Supplier: Genetex
Description: Rabbit polyclonal antibody to RDH16 (N-terminal)
Image Unavailable-77436-848

Anti-phospho-MCM2 (Ser53) Rabbit Polyclonal Antibody

Catalog Number: (77436-848)
Supplier: Bioss
Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
Image Unavailable-75790-622

Human Recombinant NIP7 (from E. coli)

Catalog Number: (75790-622)
Supplier: Prosci
Description: 60S Ribosome Subunit Biogenesis Protein NIP7 Homolog (NIP7) belongs to the NIP7 family. NIP7 contains one PUA domain, it is essential for the process of proper 27S pre-rRNA and 60S ribosome subunit assembly. NIP7 is a monomer form and interacts with NOL8 and SBDS, and may bind to RNA. In addition, NIP7 is one of the many trans-acting factors required for eukaryotic ribosome biogenesis, which interacts with nascent pre-ribosomal particles and dissociates as they complete maturation and are exported to the cytoplasm.
Image Unavailable-102497-518

Human Recombinant Fkbp2 Cc56

Supplier: Bon Opus Biosciences
Description: Bon Opus Biosciences offers quality recombinant proteins products covering a broad collection of cytokines, enzymes, diagnostic and detection reagents, and other protein-related products

Product Image-CA200062-934

Anti-STX13 Mouse Monoclonal Antibody

Catalog Number: (CA200062-934)
Supplier: Enzo Life Sciences
Description: Syntaxins are type II integral membrane proteins localized to membranes that regulate vesicle transport, protein maturation, and exocytosis. Syntaxin 1A resides in the nerve terminals of sensory neurons and nerve fibers reaching small blood vessels. Syntaxin 2 localizes to the apical plasma membrane and regulates epithelial-mesenchymal interactions. Syntaxin 6 is primarily localized to the trans-Golgi network, and partially co-localizes with AP-1 on clathrin-coated membranes. Syntaxin 13 is ubiquitously expressed and localizes to the tubular early and recycling endosomes, as well as endosomal vacuoles.
Product Image-10070-036

Anti-TP53 Rabbit Polyclonal Antibody

Catalog Number: (10070-036)
Supplier: Prosci
Description: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.
Image Unavailable-77440-528

Anti-COPG1 + COPG2 Rabbit Polyclonal Antibody

Catalog Number: (77440-528)
Supplier: Bioss
Description: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Image Unavailable-10343-858

Anti-PVRL2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10343-858)
Supplier: Bioss
Description: Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3.
Image Unavailable-10351-996

Anti-MCM5 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10351-996)
Supplier: Bioss
Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.
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