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Product Image-77392-620

SMALP BZ40 Membrane protein solubilization & stabilization

Description: The SMALP BZ series was developed in collaboration with Prof. Bert Klumperman from Nanosene, a spinout company of Stellenbosch University in South Africa. The goal was to create SMALPs that are synthesized via RAFT polymerization, achieving a better defined polymer size and a low dispersity (narrow chain length distribution). This is a significant improvement over previous SMALPs. The SMALP BZs are thus more efficient in dissolving the cell membranes and increasing protein yield.
After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
Catalog Number: 77392-620
Supplier: CUBE BIOTECH
Product Image-77392-704

Nanodisc Assembly Kit MSP1E3D1-His POPC

Description: This product is a MSP nanodisc assembly kit. It contains a vial of lyophilized membrane scaffold protein MSP1E3D1 (His-tagged) and a vial of DMPC or POPC phopshospholipid to assemble a MSP nanodisc.
Catalog Number: 77392-704
Supplier: CUBE BIOTECH
Image Unavailable-77392-616

SMALP BZ35 Membrane protein solubilization & stabilization

Description: The SMALP BZ series was developed in collaboration with Prof. Bert Klumperman from Nanosene, a spinout company of Stellenbosch University in South Africa. The goal was to create SMALPs that are synthesized via RAFT polymerization, achieving a better defined polymer size and a low dispersity (narrow chain length distribution). This is a significant improvement over previous SMALPs. The SMALP BZs are thus more efficient in dissolving the cell membranes and increasing protein yield.
After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
Catalog Number: 77392-616
Supplier: CUBE BIOTECH
Product Image-77392-850

T. californica Native AChR

Description: Our AChR is directly purified from the acetylcholine receptor of <i>Torpedo californica</i>.
Catalog Number: 77392-850
Supplier: CUBE BIOTECH
Product Image-77392-860

SARS-CoV-2 Recombinant SARS CoV-2 Spike Protein in DIBMA Glycerol (from
Hek293 Expi cells)

Description: The coronavirus, also known as SARS-CoV-2, enters the cell by using its surface SPIKE. SPIKE is processed on the cell's surface by TMPRSS2, a serine protease. It then subsequently binds to ACE2 a cell surface receptor.
Catalog Number: 77392-860
Supplier: CUBE BIOTECH
Product Image-77393-092

PureCube StrepTactin® HiCap StrepTactin® Agarose

Description: PureCube StrepTactin® agarose resin beads consist of 6% cross-linked agarose coupled to the streptactin protein.
Catalog Number: 77393-092
Supplier: CUBE BIOTECH
Product Image-77392-868

Halobacterium salinarum S10 Recombinant Sensory Rhodopsin-1 (from E. coli)

Description: Sensory rhodopsin-1 (SR-1) is a 7-transmembrane protein that acts as a phototaxis receptor in archaebacteria.
Catalog Number: 77392-868
Supplier: CUBE BIOTECH
Product Image-77392-862

SARS-CoV-2 Recombinant SARS-CoV-2 Spike Protein in SMALP 140 (from HEK293 cells)

Description: The coronavirus, also known as SARS-CoV-2, enters the cell by using its surface SPIKE. SPIKE is processed on the cell's surface by TMPRSS2, a serine protease. It then subsequently binds to ACE2 a cell surface receptor.
Catalog Number: 77392-862
Supplier: CUBE BIOTECH
Product Image-77392-844

Human Recombinant MSP2N2-D73C (from E. coli)

Description: Membrane scaffold protein, human origin.
Catalog Number: 77392-844
Supplier: CUBE BIOTECH
Product Image-77392-714

Nanodisc Msp1D1-His DMPG

Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
Catalog Number: 77392-714
Supplier: CUBE BIOTECH
Product Image-77392-722

Nanodisc MSP1D1 DMPC

Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
Catalog Number: 77392-722
Supplier: CUBE BIOTECH
Product Image-77392-572

Ultrasolute™ Amphipol 17

Description: The Ultrasolute family evolved from the first amphipol A8-35 is used for highly efficient solubilization and stabilization of membrane proteins without the use of detergents while preserving their activity. They demonstrate tolerance to moderate concentrations of divalent cations and exhibit no absorption at wavelengths >250 nm.
Catalog Number: 77392-572
Supplier: CUBE BIOTECH
Product Image-77392-592

Sulfo-SMA Membrane protein solubilization & stabilization

Description: Sulfo-SMA is an electroneutral modification of existing SMAs. It does not interfere with charge-sensitive interactions between proteins and lipids. This innovation opens up a wider range of experimental research in terms of charge-sensitive membrane protein processes like protein-protein and protein-lipid interactions. In addition, Sulfo-SMA belongs to a new generation of SMA’s which are RAFT polymerized. This achieves a reduction in both monomer size and greater monodispersity.
Another significant advantage of Sulfo polymers compared to other polymers is the wide pH range in which they remain stable. The buffer in which the polymer is supplied has a pH of 7.5, but the polymer itself remains stable between pH 4 and pH 10.
The special physicochemical properties of Sulfo-SMAs make them ideal for cryo-TEM and other downstream applications.
After successful membrane protein solubilization, the protein can be purified using affinity chromatography. For membrane protein purification, we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
Good publications to find details about Sulfo-SMA and Sulfo-DIBMA are:
Glueck et al. (2022)
Janson et al. (2022)
Eggenreich et al. (2023)
Catalog Number: 77392-592
Supplier: CUBE BIOTECH
Product Image-77392-754

Nanodisc MSP2N2 POPC

Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
Catalog Number: 77392-754
Supplier: CUBE BIOTECH
Image Unavailable-77392-610

SMALP BZ30 Membrane protein solubilization & stabilization

Description: The SMALP BZ series was developed in collaboration with Prof. Bert Klumperman from Nanosene, a spinout company of Stellenbosch University in South Africa. The goal was to create SMALPs that are synthesized via RAFT polymerization, achieving a better defined polymer size and a low dispersity (narrow chain length distribution). This is a significant improvement over previous SMALPs. The SMALP BZs are thus more efficient in dissolving the cell membranes and increasing protein yield.
After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
Catalog Number: 77392-610
Supplier: CUBE BIOTECH
Image Unavailable-77392-688

Nanodisc Assembly Kit MSP1D1-His POPC

Description: This product is a MSP nanodisc assembly kit. It contains a vial of lyophilized membrane scaffold protein MSP1D1 (His-tagged) and a vial of DMPC or POPC phopshospholipid to assemble a MSP nanodisc.
Catalog Number: 77392-688
Supplier: CUBE BIOTECH
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