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Description: M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
Catalog Number: 10109-134
Supplier: Prosci


Description: Human Glucose Transporter 3, GLUT3 ELISA Kit
Catalog Number: 76699-930
Supplier: AFG Bioscience


Description: This antibody is predicted to react with canine, human and mouse based on sequence homology. Peptidyl-prolyl cis/trans isomerases , such as PIN1, catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. PIN1 is the only PPIase that specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. PIN1-catalyzed conformational regulation has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, germ cell development, neuronal differentiation, and survival .
Catalog Number: CAPIPA5-18594
Supplier: Thermo Scientific


Description: RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
Catalog Number: 10104-052
Supplier: Prosci


Description: CAS Number: 537-39-3
MDL Number: MFCD00067496
Molecular Formula: C57H104O6
Molecular Weight: 885.45
Purity/Analysis Method: >96.0% (T)
Form: Crystal
Color: White
Melting point (°C): 42
Storage Temperature: <0°C
Catalog Number: TCT1392-001G
Supplier: TCI America

Description: Nectin-3 is a type I transmembrane glycoprotein that belongs to the nectin family. Its precursor is 549 amino acids in length and contains an extended signal sequence of 57 amino acids, an extracellular domain (ECD) of 347 amino acids, a transmembrane segment of 21 amino acids, and a cytoplasmic region of 124 amino acids. It is predominantly expressed in testis and placenta as well as in various cell lines, including epithelial cell lines. Nectin-3 plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/Nectin-2 at Sertoli-spermatid junctions. Nectin-3 is also involved in the formation of cell-cell junctions, including adherens junctions and synapses.
Catalog Number: 75789-764
Supplier: Prosci


Description: Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network in living cells, and in an in vitro system that reconstitutes this process. P40 is an effector of Rab9 that interacts preferentially with the active form of Rab9. p40 does not interact with Rab7 or K-Ras; it also fails to bind Rab9 when it is bound to GDI. The protein is found in cytosol, yet a significant fraction (~30%) is associated with cellular membranes. P40 is a very potent transport factor in that the pure, recombinant protein can stimulate, significantly, an in vitro transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network.
Catalog Number: 10082-206
Supplier: Proteintech


Description: Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase B(PPIB) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Catalog Number: 10209-218
Supplier: Boster Biological Technology


Description: Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
Catalog Number: 10348-352
Supplier: Bioss


Description: Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
Catalog Number: 10348-350
Supplier: Bioss


Description: Guarantees analysis of FAME cis/trans isomers in the C6 to C26 range.
Catalog Number: CAAGCP7489I5
Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA


Description: Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
Catalog Number: 76082-996
Supplier: Bioss


Description: This peptide is a selective PAR4 antagonist which inhibits thrombin- and PAR-4 agonist induced rat platelet aggregation.
Sequence: trans - Cinnamoyl - YPGKF - NH2
MW: 739.8 Da
% Peak Area by HPLC: ≥ 95%
Storage condition: -20°C
Catalog Number: 103010-030
Supplier: Anaspec Inc


Description: A colorimetric, non-radioactive assay for assessing cell viability and proliferation. Tetrazolium salt, XTT, is reduced to a soluble purple formazan by trans-plasma membrane electron transport from NADH via an electron mediator.
Catalog Number: 75816-750
Supplier: Cayman Chemical Company


Description: Crystalline
Catalog Number: CAAAA44540-77
Supplier: Thermo Scientific Chemicals

Description: Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network in living cells, and in an in vitro system that reconstitutes this process. P40 is an effector of Rab9 that interacts preferentially with the active form of Rab9. p40 does not interact with Rab7 or K-Ras; it also fails to bind Rab9 when it is bound to GDI. The protein is found in cytosol, yet a significant fraction (~30%) is associated with cellular membranes. P40 is a very potent transport factor in that the pure, recombinant protein can stimulate, significantly, an in vitro transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network.
Catalog Number: 10093-246
Supplier: Proteintech


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