You Searched For: armet

Catalog Number: (77223-106)

Supplier: ANTIBODIES.COM LLC

Description: Rabbit monoclonal [ARC52199] antibody to ARMET/ARP for WB with samples derived from Human, Mouse and Rat.

Catalog Number: (76731-912)

Supplier: ANTIBODIES.COM LLC

Description: Rat ARMET/ARP ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of rat ARMET/ARP in serum, plasma, tissue homogenates, and other biological fluids.

Catalog Number: (76703-346)

Supplier: AFG BIOSCIENCE LLC

Description: Human Mesencephalic Astrocyte-derived Neurotrophic Factor (ARMET) ELISA Kit

Catalog Number: (10112-454)

Supplier: Prosci

Description: Polyclonal, Host: Goat, Species: Human, Immunogen: ARMET antibody was raised against a 12 amino acid synthetic peptide near the internal region of ARMET, Application: ELISA, WB

Catalog Number: (77122-764)

Supplier: Prosci

Description: ARMET Peptide

Catalog Number: (75790-390)

Supplier: Prosci

Description: erebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues.It is belongs to the ARMET family. CDNF/ARMETL1 is a evolutionary conserved protein which can protect and restore the function of dopaminergic neurons in the rat model of Parkinson's disease, suggesting that CDNF might be beneficial for the treatment of Parkinson's disease. CDNF is widely expressed in neurons in several brain regions including cerebral cortex, hippocampus, substantia nigra, striatum and cerebellum. Human CDNF is glycosylated and secreted from transiently transfected cells. CDNF promotes the survival, growth, and function of dopamine-specific neurons and is expressed in brain regions that undergo cocaine-induced neuroplasticity.

Catalog Number: (89318-636)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to ARMET (mesencephalic astrocyte-derived neurotrophic factor)

Catalog Number: (77175-540)

Supplier: ANTIBODIES.COM LLC

Description: Human ARMET/ARP ELISA kit is a 90 minute sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human ARMET/ARP in serum, plasma, and other biological fluids.

Catalog Number: (89296-930)

Supplier: Genetex

Description: Goat polyclonal antibody to ARMET

Catalog Number: (89416-382)

Supplier: Prosci

Description: MANF Antibody: MANF, also known as ARMET, was initially identified as a protein containing an arginine-rich region that was highly mutated in a variety of tumors. More recently it was identified as a mesencephalic astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons, similar to glial cell line-derived neurotrophic factor (GDNF) and CDNF. In rat brain slices, MANF enhanced nigral gamma-aminobutyric acid release. Like GDNF and CDNF, MANF has selective neuroprotective activity for dopaminergic neurons suggesting that it may be indicated for the treatment of Parkinson's disease. Expression of MANF has also been shown to be induced during ER stress, suggesting that it may play a role in protein quality control during ER stress.

Catalog Number: (77079-396)

Supplier: ANTIBODIES.COM LLC

Description: Goat polyclonal antibody to ARMET for ELISA and WB with samples derived from Human.

Catalog Number: (76740-020)

Supplier: ANTIBODIES.COM LLC

Description: Human ARMET/ARP ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human ARMET/ARP in serum, plasma, tissue homogenates, and other biological fluids.

Catalog Number: (10082-688)

Supplier: Proteintech

Description: Anti-ARMET Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 1-182 amino acid, Format:Antigen affinity purification, Application: ELISA, Recommended Storage: - 20 C or lower

Catalog Number: (75790-392)

Supplier: Prosci

Description: Mesencephalic astrocyte-derived neurotrophic factor(MANF) is a secreted protein which belongs to the ARMET family. MANF selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. It modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. MANF enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. MANF inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. The N-terminal region of ARMET may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response. MANF reduces endoplasmic reticulum (ER) stress and has neurotrophic effects on dopaminergic neurons. Intracortical delivery of recombinant MANF protein protects tissue from ischemic brain injury. MANF has been described as a survival factor for dopaminergic neurons. MANF and a homologous protein, the conserved dopamine neurotrophic factor (CDNF), form a novel evolutionary conserved family of neurotrophic factors. MANF expression was widespread in the nervous system and non-neuronal tissues.

Catalog Number: (77231-296)

Supplier: ANTIBODIES.COM LLC

Description: Rabbit polyclonal antibody to ARMET/ARP for WB and ICC/IF with samples derived from Human, Mouse and Rat.

Catalog Number: (CAPIPA5-18829)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with canine, mouse and rat based on sequence homology. The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.