You Searched For: alix

Catalog Number: (10091-982)

Supplier: Proteintech

Description: ALG-2-interacting protein 1 (ALIX), also known as AIP1 or Hp95, is encoded by PDCD6IP gene and is involved in cell death through mechanisms involving its binding partner ALG-2 (apoptosis-linked gene-2). ALG-2 is a 22-kDa protein containing five serially repetitive EF-hand structures and is defined as a regulator of calcium-induced apoptosis following endoplasmic reticulum (ER) stress. ALIX interacts with ALG-2 through its C-terminal proline-rich region and participates in formation of multivesicular bodies. Recent finding suggest that ALIX is a critical component of caspase 9 activation and apoptosis triggered by calcium.

Catalog Number: (76729-974)

Supplier: ANTIBODIES.COM LLC

Description: Human ALIX ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human ALIX in serum, plasma, tissue homogenates, and other biological fluids.

Catalog Number: (77202-664)

Supplier: ANTIBODIES.COM LLC

Description: Human ALIX ELISA kit is a 90 minute sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human ALIX in serum, plasma, and other biological fluids.

Supplier: Biolegend

Description: Purified anti-Alix [3A9]; Isotype: Mouse IgG1, κ; Reactivity: Human, Mouse, and Frog; Apps: WB, IF, IP; Size: 100 μg

Catalog Number: (76749-570)

Supplier: Prosci

Description: Anti-PDCD6IP Rabbit Polyclonal Antibody

Catalog Number: (10084-720)

Supplier: Proteintech

Description: CHMP4B (charged multivesicular body protein 4b) is a human homologue of yeast Snf7p (also named Vps32p) and a member of CHMP family which is implicated in multivesicular body (MVB) sorting. The CHMP proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies. Among seven CHMP family members, only CHMP4 has been found to interact with Alix, a multifunctional adaptor protein in various cellular functions. This antibody is highly specific to the CHMP4B and it doesn’t cross-react with other CHMPs as well as other CHMP4s (CHMP4A and CHMP4C).

Catalog Number: (CAPIPA526536)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with chicken, mouse, Xenopus and zebrafish based on sequence homology. CHMP4B is a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.

Catalog Number: (77534-456)

Supplier: Genetex

Description: ANTIBODY ALIX 100UL GTX135226 100UL

New Product

Catalog Number: (77763-886)

Supplier: BETHYL LABORATORIES

Description: ANTIBODY RB X-ALIX A302-938A

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Catalog Number: (77534-472)

Supplier: Genetex

Description: ANTIBODY ALIX 100UL GTX135282 100UL

New Product

Catalog Number: (77769-592)

Supplier: BETHYL LABORATORIES

Description: ANTIBODY RB X-ALIX TRIAL A302-938A-T

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Catalog Number: (77517-140)

Supplier: AFG BIOSCIENCE LLC

Description: Human PDCD6IP (Programmed Cell Death Protein 6 Interacting Protein) ELISA Kit

New Product

Catalog Number: (76763-056)

Supplier: Prosci

Description: Anti-CHMP4B Rabbit Polyclonal Antibody