You Searched For: CURBELL PLASTICS


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Description: FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
Catalog Number: CAPIPA5-13411
Supplier: Thermo Scientific


Description: The protein encoded by this gene is similar to an iron transport protein found in mouse. The mouse protein is similar to ceruloplasmin, a serum multi-copper ferroxidase, and is thought to be a membrane-bound protein responsible for transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system. In mouse, defects in this gene can lead to severe microcytic anemia. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
Catalog Number: 89358-306
Supplier: Genetex


Description: This shoe brush machine is designed with four transmission-driven brushes, including a floating weight-loaded top brush and rotating bottom brush that clean sides, top, and bottom of shoes prior to entry into contamination-controlled areas.
Catalog Number: 21924-463
Supplier: Liberty Industries

Small Business Enterprise


Description: Heavy-duty stage ramp carts are used every day in conjunction with our stage and stage ramp units. High-quality state-of-the-art guard rail carts are safe, durable, easy to operate, and a great long-term value. Carts are perfect for heavy-use and heavy-turn settings providing years of trusted service.
Catalog Number: 76180-420
Supplier: AmTab Manufacturing Corporation

Environmentally Preferable


Description: Bacto Casamino Acids is an animal origin (AO) acid hydrolysis of casein. This supplement contains low salt and iron content making it an excellent supplement for media formulations where nitrogen requirements are minimal.
Catalog Number: CA76628-904
Supplier: Thermo Fisher Scientific


Description: VACUETTE® trace element tubes are designed to test trace elements such as aluminum, lead, cadmium, chrome, iron, fluoride, cobalt, copper, lithium, manganese, molybdenum, mercury, selenium, or thalium.
Catalog Number: 95057-259
Supplier: Greiner Bio-One

Description: Chicken polyclonal IgY Antibodies against Transferrin, antigen affinity-purified. Transferrin is a major iron binding serum protein and is found in human plasma or serum at concentrations of 3 mg/ml. M.W: 80,000.
Catalog Number: 10071-166
Supplier: Prosci


Description: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Catalog Number: 10103-356
Supplier: Prosci


Description: CISD2 Antibody: Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are a cause of the neurodegenerative disorder Wolfram syndrome 2. CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum and mitochondria and binds an iron/sulfur cluster. CISD2 interacts with Bcl-2 and can be displaced by the BH3-only protein BIK and contributes to the regulation of BIK-initiated autophagy. CISD2 deficiency in mice causes mitochondrial breakdown accompanied by autophagic cell death as well as the development of premature aging phenotype.
Catalog Number: 10751-942
Supplier: Prosci


Description: Sterile-filtered. A major iron storage protein. Suitable for use in immunoassays, as an immunogen, and in enzyme/radiolabeling. Prepared from tissues of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Catalog Number: CA80056-442
Supplier: MilliporeSigma

Description: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
Catalog Number: 77438-326
Supplier: Bioss


Description: Haptoglobin, Mixed type. Haptoglobin combines with free plasma hemoglobin, prevent loss of iron through the kidneys and protect the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes.
Catalog Number: 10071-104
Supplier: Prosci


Description: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Catalog Number: CAPIPA5-18407
Supplier: Thermo Scientific


Description: CISD2 Antibody: Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are a cause of the neurodegenerative disorder Wolfram syndrome 2. CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum and mitochondria and binds an iron/sulfur cluster. CISD2 interacts with Bcl-2 and can be displaced by the BH3-only protein BIK and contributes to the regulation of BIK-initiated autophagy. CISD2 deficiency in mice causes mitochondrial breakdown accompanied by autophagic cell death as well as the development of premature aging phenotype.
Catalog Number: 10061-882
Supplier: Prosci


Description: These heavy-duty table carts are used every day throughout the world in multi-purpose environments. High-quality state-of-the-art table carts are safe, durable, easy to operate, and perfect for heavy-use and heavy-turn settings providing years of trusted service.
Catalog Number: 76179-692
Supplier: AmTab Manufacturing Corporation

Environmentally Preferable


Description: For use with 5000-series respirators.
Catalog Number: CA43100-074
Supplier: 3M