You Searched For: Z-Arg-pNA·HCl

Supplier: Bachem Americas

Description: Melanin-concentrating hormone (MCH), originally isolated from salmon pituitary glands, has also been found in the mammalian CNS. In lower vertebrates, salmon MCH alters pigmentation by inducing melanosome aggregation within melanocytes of teleost fish, whereas it causes melanosome dispersion in amphibians and reptiles. The biological role of MCH in higher vertebrates, however, is not yet fully understood, but it may function as a neuromodulator and hypophysiotropic agent in the secretion of α-MSH, ACTH, and GH.

Catalog Number: (89146-892)

Supplier: Enzo Life Sciences

Description: Substrate for MMP-2 and -9

Supplier: Bachem Americas

Description: 1G CAS: 15706-88-4 C10H19N5O5 FW: 289.29

Supplier: Bachem Americas

Description: 1G CAS: 60461-10-1 C11H23N5O3S FW: 305.4

Catalog Number: (G-2480.0001BA)

Supplier: Bachem Americas

Description: 1G CAS: 26607-15-8 C12H25N5O3 FW: 287.36

Supplier: Bachem Americas

Description: The dipeptide Arg-Phe mimics the haemodynamic effects of FMRF amide. Both peptides increased blood pressure and heart rate in anaesthesized rats by central stimulation of the sympathetic nervous system, RF being approximately 4 fold more potent.

Catalog Number: (H-2970.0100BA)

Supplier: Bachem Americas

Description: 100mg CAS: 104809-29-2 C21H35N7O3 FW: 433.55

Catalog Number: (H-1780.0001BA)

Supplier: Bachem Americas

Description: The major physiological roles of Arg-Vasopressin are regulation of water balance in animals (antidiuretic action) and contraction of arterioles (vasopressor action). CAS number (argipressin acetate): 129979-57-3.

Supplier: Bachem Americas

Description: A salt taste-enhancing dipeptide.

Catalog Number: (77437-586)

Supplier: Bioss

Description: Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. Citrullinates histone H1 at 'Arg-54' (to form H1R54Ci), histone H3 at 'Arg-2', 'Arg-8', 'Arg-17' and/or 'Arg-26' (to form H3R2ci, H3R8ci, H3R17ci, H3R26ci, respectively) and histone H4 at 'Arg-3' (to form H4R3ci). Acts as a key regulator of stem cell maintenance by mediating citrullination of histone H1: citrullination of 'Arg-54' of histone H1 (H1R54Ci) results in H1 displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell maintenance. Promotes profound chromatin decondensation during the innate immune response to infection in neutrophils by mediating formation of H1R54Ci. Citrullination of histone H3 prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.

Supplier: Bachem Americas

Description: Sequence: Fmoc-Arg(Tos)-OH

Supplier: Mortech Manufacturing

Description: All control slides are on Mopec IHC Enhanced Hydrophilic Adhesive Slides using Formalin Fixed Paraffin Embedded (FFPE) human tissue.

Supplier: Bachem Americas

Description: The ANP antagonist A71915 inhibits ANP-induced cGMP stimulation.

Catalog Number: (10072-532)

Supplier: Prosci

Description: Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Kex-2 cleaves at the carboxyl end of the recognition sequences Arg-Arg/X and Lys-Arg/X. Recombinant Yeast Kex-2 is a 59.9 kDa protease consisting of 554 amino acid residues.

Catalog Number: (89161-192)

Supplier: Enzo Life Sciences

Description: MMP substrate

Supplier: New England Biolabs (NEB)

Description: Furin is a ubiquitous subtilisin-like proprotein convertase. It is the major processing enzyme of the secretory pathway and is localized in the trans-golgi network. Substrates of Furin include blood clotting factors, serum proteins and growth factor receptors such as the insulin-like growth factor receptor. The minimal cleavage site is Arg-X-X-Arg'. However, the enzyme prefers the site Arg-X-(Lys/Arg)-Arg'. An additional arginine at the P6 position appears to enhance cleavage. Furin is inhibited by EGTA, α1- Antitrypsin Portland and polyarginine compounds.