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Supplier: Thermo Scientific Chemicals
Description: Cobalt(II,III) oxide ≥99% (metals basis), nanopowder
Supplier: PIP
Description: The QRP VHC12 ESD-Safe Clean Room Class 100 Vinyl ISO 5 Gloves are 100% PVC co-polymer (no latex) for ISO 5 (Class 100) applications.

Supplier: Thermo Scientific Chemicals
Description: Gadolinium(III) carbonate hydrate ≥99% (REO, rare earth oxide basis)
Catalog Number: (103010-350)
Supplier: Anaspec Inc
Description: HiLyte™ Fluor 555 acid, SE is an excellent amine-reactive fluorescent labeling dye that generates the protein conjugates that are only slightly red-shifted compared to those of Cy™ 3 dyes, resulting in an optimal match to filters designed for CyTM dyes.


Supplier: TCI America
Description: [for Colorimetric Analysis of Co, Cd]
CAS Number: 50768-79-1
MDL Number: MFCD00059780
Molecular Formula: C11H9Br2N5
Molecular Weight: 371.04
Purity/Analysis Method: >98.0% (T)
Form: Crystal

SDS

Catalog Number: (10102-080)
Supplier: Prosci
Description: RERE is a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. RERE co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development.This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene.


Catalog Number: (10749-066)
Supplier: Prosci
Description: DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans. It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles. DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor.


Supplier: Biotium
Description: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Catalog Number: (103007-156)
Supplier: Anaspec Inc
Description: The sequence of this synthetic peptide is based on the primary site of cleavage by plasmepsin II (PM II) within hemoglobin (Hb), and numbering of the peptide corresponds to the residue within the a-chain of Hb. Plasmepsins are involved in the early steps of hemoglobin degradation. They are able to recognize intact hemoglobin and make an initial cleavage in the B helix of the hemoglobin a-chain between Phe-33 and Leu-34.
Sequence:EDANS-CO-CH2-CH2-CO-ALERMFLSFP-Dap(DABCYL)OH
MW:1896 Da
% peak area by HPLC:95
Storage condition:-20° C


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00016017 Soluble in water, methanol, ethanol, acetone, methyl acetate
Catalog Number: (10141-170)
Supplier: Tonbo Biosciences
Description: The UC10-4F10-11 antibody is specific for mouse CD152, commonly known as CTLA-4, a 33-37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negative regulator of T cell activation and may contribute to the suppressor function of Treg cells.


Catalog Number: (77437-774)
Supplier: Bioss
Description: Plexins are a family of large integral membrane proteins that complex with neuropilins to form semaphorin co-receptors. The extracellular region of plexins contain a semaphorin domain, multiple glycine rich motifs, and MET related sequences. The cytoplasmic region contains a Sex/Plexin domain and putative tyrosine phosphorylation sites that mediate signal transduction after activation. This region in Plexin A1 binds the RhoGTPases, Rnd1 and RhoD. Recruitment of Rnd1 has been implicated in the cytoskeletal collapse that occurs after semaphorin mediated activation of Plexin A1, while RhoD may block this collapsing activity through interaction with the cytoplasmic region of Plexin A1. The expression of Plexin A1, along with the co receptor Neuropilin 1, is upregulated in neurons after central nervous system injury. The axons from these neurons cannot cross semaphorin 3A containing regions at the site of injury. Thus, semaphorin 3A and its co-receptors, Plexin A1 and Neuropilin 1, may have significant roles in axon regeneration after neuronal injury.


Supplier: Thermo Scientific Chemicals
Description: Gadolinium(III) carbonate hydrate ≥99.99% (REO, rare earth oxide basis), REacton®
Catalog Number: (CAAA40836-KS)
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00010935 Notes: Thickness tolerance: +/- 0.015in; Diameter tolerance: +0.020/-0.0in

Catalog Number: (10107-492)
Supplier: Prosci
Description: ZNF446 contains a KRAB and three C (2)H (2) zinc fingers. ZNF446 is a transcription repressor when fused to GAL4 DNA-binding domain and co-transfected with VP-16. Overexpression of ZNF446 in COS-7 cells inhibits the transcriptional activities of SRE and AP-1, suggesting that the ZNF446 protein may act as a transcriptional repressor in mitogen-activated protein kinase (MAPK) signaling pathway to mediate cellular functions.


Supplier: Transforming Technologies
Description: The MT4000-Texture series ESD-safe 2-layer rubber matting is made of 100% co-extruded rubber.

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