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You Searched For: Cinnamyl+alcohol


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Image Unavailable-102981-186

Aftin-5 ≥98% (by NMR)

Description: Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Abeta42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds).
Catalog Number: 102981-186
Supplier: Adipogen
Image Unavailable-ABCA_AB285376-1MG

AFTIN-5 AB285376-1MG

Description: AFTIN-5 AB285376-1MG
Catalog Number: ABCA_AB285376-1MG
Supplier: Abcam

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Image Unavailable-ABCA_AB285376-5MG

AFTIN-5 AB285376-5MG

Description: AFTIN-5 AB285376-5MG
Catalog Number: ABCA_AB285376-5MG
Supplier: Abcam

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