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Image Unavailable-10430-474

Anti-RNF139 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10430-474)
Supplier: Bioss
Description: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Image Unavailable-10430-466

Anti-RNF139 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10430-466)
Supplier: Bioss
Description: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Image Unavailable-75913-834

Anti-CD47 Mouse Monoclonal Antibody [clone: IAP/964 B6H12.2]

Supplier: Biotium
Description: This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Image Unavailable-75913-782

Anti-CD47 Mouse Monoclonal Antibody [clone: IAP/964]

Supplier: Biotium
Description: This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Product Image-10102-840

Anti-SGCB Rabbit Polyclonal Antibody

Catalog Number: (10102-840)
Supplier: Prosci
Description: SGCB is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix.The dystrophin-glycoprotein complex (DGC) is a multisubunit protein complex that spans the sarcolemma and provides structural linkage between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. There are 3 main subcomplexes of the DGC: the cytoplasmic proteins dystrophin (DMD; MIM 300377) and syntrophin (SNTA1; MIM 601017), the alpha- and beta-dystroglycans (see MIM 128239), and the sarcoglycans (see, e.g., SGCA; MIM 600119) (Crosbie et al., 2000 [PubMed 10942431]).
Image Unavailable-10663-558

Anti-GIPC-2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10663-558)
Supplier: Bioss
Description: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Image Unavailable-76082-356

Anti-GLUT12 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76082-356)
Supplier: Bioss
Description: GLUT12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion. Thirteen different types of glucose/fructose transport carrier proteins designated as Glut 1-13 facilitate glucose/fructose transport across the cell membrane. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers.
Image Unavailable-10399-464

Anti-ANXA7 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10399-464)
Supplier: Bioss
Description: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.
Image Unavailable-10405-954

Anti-ANXA7 Rabbit Polyclonal Antibody

Catalog Number: (10405-954)
Supplier: Bioss
Description: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.
Image Unavailable-76117-728

Anti-RNF139 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76117-728)
Supplier: Bioss
Description: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Image Unavailable-76100-002

Anti-HHAT Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Catalog Number: (76100-002)
Supplier: Bioss
Description: HHAT is a 493 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyze the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1.
Image Unavailable-75913-774

Anti-CD47 Mouse Monoclonal Antibody [clone: B6H12.2]

Catalog Number: (75913-774)
Supplier: Biotium
Description: This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
Image Unavailable-10414-302

Anti-PMVK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10414-302)
Supplier: Bioss
Description: PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart, liver, skeletal muscle, kidney, and pancreas with lower expression in brain, placenta and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.
Image Unavailable-77440-564

Anti-CTTNBP2NL Rabbit Polyclonal Antibody

Catalog Number: (77440-564)
Supplier: Bioss
Description: CTTNBP2NL is a 639 amino acid protein that is encoded by a gene that maps to human chromosome 1p13.2. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Image Unavailable-89266-188

Anti-MS4A4A Rabbit Polyclonal Antibody

Catalog Number: (89266-188)
Supplier: Genetex
Description: Rabbit polyclonal antibody to MS4A4A (N-terminal)
Image Unavailable-10491-534

Anti-LAPTM4A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10491-534)
Supplier: Bioss
Description: Lysosomal-associated transmembrane protein 4A (LAPTM4A), also known as Golgi 4-transmembrane spanning transporter MTP, is a 233 amino acid protein belonging to the LAPTM5/LAPTM5 transporter family. LAPTM4A is subcellularly localized to the intracytoplasmic membrane and has the potential to reside in intracellular membrane-bound compartments. LAPTM4A is thought to function as a transporter of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of intracellular compartments. LAPTM4A is predicted to have four transmembrane domains, with the C-terminal domain being required for retention of the protein within intracellular membranes.
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