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Product Image-10110-556

Anti-MAS1 Rabbit Polyclonal Antibody

Catalog Number: (10110-556)
Supplier: Prosci
Description: The structure of MAS1 indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.
Product Image-10751-182

Anti-KL Rabbit Polyclonal Antibody

Catalog Number: (10751-182)
Supplier: Prosci
Description: KLOTHO Antibody: KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.
Image Unavailable-CAAAAL11435-30

Sorbitan monostearate

Supplier: Thermo Scientific Chemicals
Description: Emulsifier used in cosmetics, pharmaceuticals and food preparation

Certificates

Product Image-10110-554

Anti-MAS1 Rabbit Polyclonal Antibody

Catalog Number: (10110-554)
Supplier: Prosci
Description: The structure of MAS1 indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.
Product Image-10099-748

Anti-RNF139 Rabbit Polyclonal Antibody

Catalog Number: (10099-748)
Supplier: Prosci
Description: RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Image Unavailable-75979-786

Anti-VWF Mouse Monoclonal Antibody [clone: VWF635]

Supplier: Biotium
Description: Von Willebrand Factor, Monoclonal antibody, Clone: VWF635, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Recombinant vWF fragment spanning aa 845-949, Synonyms: Coagulation Factor VIII, Application: IF, Size: 500uL

Image Unavailable-75979-526

Anti-VWF Mouse Monoclonal Antibody [clone: 3E2D10]

Supplier: Biotium
Description: Von Willebrand Factor, Monoclonal antibody, Clone: 3E2D10, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Recombinant vWF fragment spanning aa 845-949, Synonyms: Coagulation Factor VIII, Application: IF, Size: 500uL

Image Unavailable-75979-590

Anti-VWF Mouse Monoclonal Antibody (Biotin) [clone: 3E2D10 VWF635]

Supplier: Biotium
Description: Von Willebrand Factor, Monoclonal antibody, Clone: 3E2D10 + VWF635, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Recombinant human vWF fragment spanning aa 845-949, Synonyms: Coagulation Factor VIII, Size: 100uL

Product Image-76460-012

SP Wilmad-LabGlass, Variable Temperature NMR Spinner Turbine for use with Bruker® Spectrometers, SP Industries

Catalog Number: (76460-012)
Supplier: SP Industries
Description: Manufactured to precision standards that exceed the spectrometer manufacturers requirements.
Image Unavailable-10475-470

Anti-HIAT1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10475-470)
Supplier: Bioss
Description: The Major facilitator superfamily consists of presumed carbohydrate transporters with 10-12 membrane-spanning domains. Belonging to the facilitator superfamily, HIAT1 is a 490 amino acid multi-pass membrane protein that may function as a sugar transporter and is expressed in adult and embryonic brain. The HIAT1 gene was first observed while analyzing for active genes in neonatal mouse hippocampus. The gene encoding HIAT1 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. Stickler syndrome, Parkinsons, schizophrenia, familial adenomatous polyposis, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Product Image-10102-442

Anti-EFEMP1 Rabbit Polyclonal Antibody

Catalog Number: (10102-442)
Supplier: Prosci
Description: EFEMP1 gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy.This gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy.
Image Unavailable-CA71002-432

Sorbitan monooleate

Supplier: Spectrum Chemicals
Description: Sorbitan Monooleate, also known as polysorbate 80, is a nonionic emulsifier and surfactant and used in cosmetics and foods.

Certificates

Image Unavailable-75978-930

Anti-VWF Mouse Monoclonal Antibody (Biotin) [clone: 3E2D10]

Supplier: Biotium
Description: Von Willebrand Factor, Monoclonal antibody, Clone: 3E2D10, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Recombinant human vWF fragment spanning aa 845-949, Synonyms: Coagulation Factor VIII, Application: IF, Size: 100uL

Image Unavailable-75979-578

Anti-VWF Mouse Monoclonal Antibody [clone: 3E2D10 VWF635]

Supplier: Biotium
Description: Von Willebrand Factor, Monoclonal antibody, Clone: 3E2D10 + VWF635, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Recombinant human vWF fragment spanning aa 845-949, Synonyms: Coagulation Factor VIII, Size: 500uL

Product Image-10071-452

Anti-SHC1 Rabbit Polyclonal Antibody

Catalog Number: (10071-452)
Supplier: Prosci
Description: Signaling adapter that couples activated growth factor receptors to signaling pathway. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span
Image Unavailable-75979-640

Anti-VWF Mouse Monoclonal Antibody [clone: 3E2D10 VWF635]

Catalog Number: (75979-640)
Supplier: Biotium
Description: Von Willebrand Factor, Monoclonal antibody, Clone: 3E2D10 + VWF635, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, BSA-free, Immunogen: Recombinant human vWF fragment spanning aa 845-949, Synonyms: Coagulation Factor VIII, Size: 50 uL
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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