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Image Unavailable-76101-656

Anti-GRM2+GRM4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76101-656)
Supplier: Bioss
Description: L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Image Unavailable-76101-654

Anti-GRM2+GRM4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76101-654)
Supplier: Bioss
Description: L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Image Unavailable-CA61000-136

Mineral Modified Glutamate Medium Base, HiMedia Laboratories

Catalog Number: (CA61000-136)
Supplier: HiMedia
Description: Base medium is used for enumeration of coliform bacteria in water and waste water.

SDS Certificates


Image Unavailable-TCB4083-5G

N-(tert-Butoxycarbonyl)-L-pyroglutamic acid ≥98.0% (by HPLC, titration analysis)

Catalog Number: (TCB4083-5G)
Supplier: TCI America
Description: CAS Number: 53100-44-0
MDL Number: MFCD00672316
Molecular Formula: C10H15NO5
Molecular Weight: 229.23
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 119
Specific rotation [a]20/D: -34 deg (C=1, CHCl3)
Storage Temperature: 0-10°C

SDS


Image Unavailable-89358-714

Anti-SLC25A22 Rabbit Polyclonal Antibody

Catalog Number: (89358-714)
Supplier: Genetex
Description: The SLC25 gene family encodes mitochondrial carriers that transport a variety of metabolites across the inner mitochondrial membrane (Palmieri, 2004 [PubMed 14598172]). SLC25A22, also known as GC1, is 1 of the 2 mitochondrial glutamate/H+ symporters, the other being SLC25A18 (MIM 609303).[supplied by OMIM]
Image Unavailable-103007-392

Glutamate Receptor Endocytosis Inhibitor

Catalog Number: (103007-392)
Supplier: Anaspec Inc
Description: This GluR23Y peptide was used in ELISA cell-surface assay for the insulin-stimulated endocytosis of native AMPA receptors in cultured hippocampal neurons. GluR23Y prevented any insulin-induced reduction. The blockade of insulin action was observed when the GluR23Y peptide was delivered into neurons by fusing it to the membrane transduction domain of HIV-1.
Sequence:YKEGYNVYG
MW:1092.2 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-10414-024

Anti-GRIA2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10414-024)
Supplier: Bioss
Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Image Unavailable-10414-022

Anti-GRIA2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10414-022)
Supplier: Bioss
Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Image Unavailable-10414-030

Anti-GRIA2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10414-030)
Supplier: Bioss
Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Product Image-89152-594

2-Phosphonomethyl pentanedioic acid ≥97% (by HPLC)

Catalog Number: (89152-594)
Supplier: Enzo Life Sciences
Description: Potent inhibitor of the neuropeptidase N-acetylated α-linked acidic dipeptidase (NAALADase), which is a membrane-bound peptidase that hydrolyses N-acetyl-L-aspartate-L-glutamate (NAAG), a major brain peptide.
Image Unavailable-10090-192

Anti-MGLUR1 Rabbit Polyclonal Antibody

Catalog Number: (10090-192)
Supplier: Proteintech
Description: GRM1, also named as GPRC1A and MGLUR1, belongs to the G-protein coupled receptor 3 family. GRM1 is a receptor for glutamate. The activity of GRM1 is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. It may participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum. The antibody can recognize isoform1 and isoform2 of GRM1.
Image Unavailable-CAPIPA5-18094

Anti-GTRAP3-18/JWA Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18094)
Supplier: Thermo Scientific
Description: Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.
Image Unavailable-10484-818

Anti-GRIA1 Rabbit Polyclonal Antibody

Catalog Number: (10484-818)
Supplier: Bioss
Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Image Unavailable-89264-996

Anti-GRM1 Rabbit Polyclonal Antibody

Catalog Number: (89264-996)
Supplier: Genetex
Description: Rabbit polyclonal antibody to mGluR1
Image Unavailable-B-1595.0005BA

Fmoc-Glu-OtBu

Supplier: Bachem Americas
Description: Sequence: Fmoc-Glu-OtBu

Product Image-10100-010

Anti-GPT2 Rabbit Polyclonal Antibody

Catalog Number: (10100-010)
Supplier: Prosci
Description: GPT and GPT2 (EC 2.6.1.2), also known as alanine transaminases, are pyridoxal enzymes that catalyze the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. By mediating the conversion of these 4 major intermediate metabolites, these transaminases have roles in gluconeogenesis and in amino acid metabolism.GPT (MIM 138200) and GPT2 (EC 2.6.1.2), also known as alanine transaminases, are pyridoxal enzymes that catalyze the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. By mediating the conversion of these 4 major intermediate metabolites, these transaminases have roles in gluconeogenesis and in amino acid metabolism.
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