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Anti-MUC1 Mouse Monoclonal Antibody (CF488A) [clone: MUC1/955]

Supplier: Biotium
Description: This MAb reacts with MUC1. The dominant epitope of this MAb has not yet been determined. MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and over expressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four c-erbB receptors and localize with c-erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Product Image-CA28306-368

VWR® Quantitative Filter Paper, Grade 474

Supplier: VWR International
Description: Uses include filtration of aluminum phosphate, zinc ammonium phosphate, and silver chromate.

Certificates

Product Image-10094-798

Anti-Sodium iodide symporter Rabbit Polyclonal Antibody

Catalog Number: (10094-798)
Supplier: Proteintech
Description: The sodium iodide symporter (Na+/I - symporter, NIS), encoded by SLC5A5, is an integral plasma membrane glycoprotein that plays an important role in iodide uptake by thyroid cells. Expression of sodium iodide symporter has also been found in extra-thyroidal tissues, including gastric mucosa, lactating mammary gland and salivary glands. Increased expression of sodium iodide symporter has been found in thyroid tissue from patients with Graves’ disease as well as papillary thyroid carcinomas. In addition, sodium iodide symporter was found to express in majority of breast cancer tissue but not in normal tissue. Sodium iodide symporter can be a promising diagnostic and therapeutic tool for thyroid cancer and breast cancer. This antibody recognizes the mature approximately 75-100 kDa protein and a partially glycosylated 50-55 kDa protein. (12588808, 9525971)
Image Unavailable-10407-250

Anti-CEL Rabbit Polyclonal Antibody

Catalog Number: (10407-250)
Supplier: Bioss
Description: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat(VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq].
Image Unavailable-76101-276

Anti-ADH/AVP/ARVP Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76101-276)
Supplier: Bioss
Description: Vasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a posterior pituitary hormone that is synthesised in the hypothalamus. Vasopressin is synthesised as a precursor protein that consists of arginine vasopressin and two associated proteins, neurophysin 2 and the glycopeptide copeptin. Vasopressin, together with its carrier protein neurophysin II, is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. Vasopressin can also contract smooth muscle during parturition and lactation. It also plays a role in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in the vasopressin precursor cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI), which is characterised by persistant thirst, polydipsia and polyuria.
Image Unavailable-76101-274

Anti-ADH/AVP/ARVP Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76101-274)
Supplier: Bioss
Description: Vasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a posterior pituitary hormone that is synthesised in the hypothalamus. Vasopressin is synthesised as a precursor protein that consists of arginine vasopressin and two associated proteins, neurophysin 2 and the glycopeptide copeptin. Vasopressin, together with its carrier protein neurophysin II, is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. Vasopressin can also contract smooth muscle during parturition and lactation. It also plays a role in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in the vasopressin precursor cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI), which is characterised by persistant thirst, polydipsia and polyuria.
Image Unavailable-CAPIPA526701

Anti-NEU1 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA526701)
Supplier: Thermo Scientific
Description: There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
Image Unavailable-76120-908

Anti-PauA Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76120-908)
Supplier: Bioss
Description: Plasminogen activator A (PauA) is a Streptococcus uberis protein that functions similarly to proteins within the Staphylokinase/Streptokinase family. Streptococcus uberis is a common cause of infection and inflammatory disease in the bovine udder. Inflammation of breast tissue (mastitis) has been recognized as a serious threat to the welfare of the dairy cow and has a severe economic impact on the dairy industry. S. uberis has been shown to specifically activate bovine and ovine plasminogen and this is mediated by the extracellular protein, plasminogen activator uberis (PauA), which has a molecular mass of around 30 kDa. It has been postulated that activation of plasminogen by PauA may facilitate early bacterial colonization of the lactating gland by promoting the release of nutrients which are likely to be restricted in milk.
Product Image-95057-187

VACUETTE® Glycolytic Inhibitor Tubes, Greiner Bio-One

Supplier: Greiner Bio-One
Description: Ideal for use in glucose and lactate determinations, tubes contain an anticoagulant (potassium oxalate) and a stabilizer (sodium fluoride).

Certificates Product available on GSA Advantage®

Image Unavailable-CA76634-514

Anti-Adipophilin Mouse Monoclonal Antibody [clone: DBM15.60]

Catalog Number: (CA76634-514)
Supplier: Diagnostic Biosystems
Description: Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
Product Image-470336-184

Wards® Stoichiometry of Copper and Silver Nitrate

Catalog Number: (470336-184)
Supplier: Ward's Science
Description: An introduction to stoichiometry through the formation of solid silver on a copper wire.
Product Image-470302-402

Silver Nitrate

Supplier: Ward's Science
Description: CAS Number: 7761-88-8
Formula: AgNO3
Density: 4.35 g/mL
Freezing Point: 212 °C
Solubility: Water, Hot Alcohol
Shelf Life: 24 Months

SDS

Image Unavailable-TCS0977-5G

Silver(I) trifluoromethanethiolate ≥95.0% (by titrimetric analysis)

Supplier: TCI America
Description: Silver(I) Trifluoromethanethiolate, Purity/Analysis Method: >95.0%(T), CAS Number: 811-68-7, Molecular formula: CAgF3S, Molecular weight: 208.93, Synonym: Trifluoromethanethiol Silver(I) Salt, Size: 1G

Certificates

Product Image-470302-372

Silver Chloride

Catalog Number: (470302-372)
Supplier: Ward's Science
Description: CAS Number: 7783-90-6
Formula Weight: 143.32
Formula: AgCl
Hazard Info: Toxic
Density (g/mL): 5.56
Boiling Point (°C): 1550
Freezing Point (°C): 455
Solubility: Water, Ammonium Hydroxide, Sulfuric Acid, Sodium Thiosulfate and Potassium Bromide Solution
Synonyms: Chloride Salt of Silver
Shelf Life (months): 36
Storage: Green

SDS


Image Unavailable-76108-214

Anti-CABC1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76108-214)
Supplier: Bioss
Description: May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain.Tissue specificity:Ubiquitously expressed with a relatively greater abundance in heart and skeletal muscle.Involvement in disease:Defects in ADCK3 are a cause of coenzyme Q10 deficiency (CoQ10 deficiency). CoQ10 deficiency is an autosomal recessive disorder with variable manifestations. It can be associated with three main clinical phenotypes: a predominantly myopathic form with central nervous system involvement, an infantile encephalomyopathy with renal dysfunction and an ataxic form with cerebellar atrophy.Defects in ADCK3 are the cause of spinocerebellar ataxia autosomal recessive type 9 (SCAR9) [MIM:612016]; also known as autosomal recessive cerebellar ataxia type 2 (ARCA2). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR9 is an autosomal recessive form characterized by gait ataxia and cerebellar atrophy with slow progression and few associated features. Patients can manifest brisk tendon reflexes and Hoffmann sign, mild psychomotor retardation, mild axonal degeneration of the sural nerve, exercise intolerance and elevated serum lactate.
Image Unavailable-76108-216

Anti-CABC1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76108-216)
Supplier: Bioss
Description: May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain.Tissue specificity:Ubiquitously expressed with a relatively greater abundance in heart and skeletal muscle.Involvement in disease:Defects in ADCK3 are a cause of coenzyme Q10 deficiency (CoQ10 deficiency). CoQ10 deficiency is an autosomal recessive disorder with variable manifestations. It can be associated with three main clinical phenotypes: a predominantly myopathic form with central nervous system involvement, an infantile encephalomyopathy with renal dysfunction and an ataxic form with cerebellar atrophy.Defects in ADCK3 are the cause of spinocerebellar ataxia autosomal recessive type 9 (SCAR9) [MIM:612016]; also known as autosomal recessive cerebellar ataxia type 2 (ARCA2). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR9 is an autosomal recessive form characterized by gait ataxia and cerebellar atrophy with slow progression and few associated features. Patients can manifest brisk tendon reflexes and Hoffmann sign, mild psychomotor retardation, mild axonal degeneration of the sural nerve, exercise intolerance and elevated serum lactate.
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