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Catalog Number: (76100-606)
Supplier: Bioss
Description: Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.


Catalog Number: (10852-848)
Supplier: Restek
Description: Use a spanner wrench to easily remove a nut from an FID collector without damaging the nut.


Catalog Number: (76107-676)
Supplier: Bioss
Description: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA <i>in vitro</i>. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity). The CCR4-NOT complex functions as general transcription regulation complex. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.


Supplier: Avantor

Supplier: DWK Life Sciences (KIMBLE)
Description: MicroLiter's product line of sample vials offer superior storage and handling of larger volume samples.
Catalog Number: (77392-760)
Supplier: CUBE BIOTECH
Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.


Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: These high quality components are made of stainless steel and polymer that resists organic solvents and corrosion. They can be easily assembled to make a stand-alone setup for student laboratory equipment or to make a complicated frame for research labs.

New Product

Catalog Number: (35756-408)
Supplier: Antyila Scientific
Description: One 1L siliconized borosilicate glass vessel for Biological Stirrer (35756-418). Includes seals, caps and stirrer rod assembly. Actual volume is approximately twice the nominal working volume. Space-saving design. For 110V, 50/60Hz operation.


Supplier: Leica Microsystems
Description: We move the laser, not the sample. And we use gravity for collection. LMD systems provides perfectly cut, contamination-free, analysis-ready dissectates.

Catalog Number: (77392-762)
Supplier: CUBE BIOTECH
Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.


Catalog Number: (76100-608)
Supplier: Bioss
Description: Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.


Supplier: BRAINSTORM STUDIOS, LLC
Description: <p><span style="color:black">Assemble a functional trebuchet to explore motion, force, and energy concepts.</span></p>

New Product

Catalog Number: (10390-952)
Supplier: Bioss
Description: UQCRC2 is a component of the ubiquinol cytochrome c reductase complex (complex III), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.


Catalog Number: (76415-960)
Supplier: Corning
Description: Axygen® offers a comprehensive line of tips for Beckman Coulter® automation systems. These tips are manufactured to stringent specifications under strict process controls and assembled via automation to ensure consistent performance and quality.

Environmentally Preferable


Catalog Number: (10390-958)
Supplier: Bioss
Description: UQCRC2 is a component of the ubiquinol cytochrome c reductase complex (complex III), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.


Catalog Number: (10110-890)
Supplier: Prosci
Description: COIL is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies.The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.


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