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Description: This product has been assayed against 1.0 µg of Rat IgG in a standard capture ELISA using pNPP p-nitrophenyl phosphate as a substrate for 30 minutes at room temperature.
Catalog Number: CA612-6502
Supplier: Rockland Immunochemical


Description: This product has been assayed against 1.0 µg of Rat IgG in a standard capture ELISA using pNPP (p-nitrophenyl phosphate) as a substrate for 30 minutes at room temperature.
Catalog Number: CA612-9502
Supplier: Rockland Immunochemical


Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Catalog Number: 75977-342
Supplier: Biotium


Description: Antibody Anti-Goat IgG (H&L) is suitable for immunoblotting (western or dot blot), ELISA, immunoelectron microscopy and immunochemistry as well as other antibody-based enzymatic assays requiring lot-to-lot consistency.
Catalog Number: CA605-705-002
Supplier: Rockland Immunochemical


Description: Anti-Chicken IgG whole molecule is suitable for use in immunoelectrophoresis, western-blot, competitive western-blot, ELISA and competitive ELISA assays. Specific conditions for reactivity and signal detection should be optimized by the end user.
Catalog Number: CA603-105-126
Supplier: Rockland Immunochemical


Description: Suitable for immunoblotting (western or dot blot), ELISA and immunochemistry as well as other antibody based enzymatic assays requiring extremely low background levels, lot-to-lot consistency, high titer and specificity.
Catalog Number: CA614-1502
Supplier: Rockland Immunochemical


Description: Anti-Chicken IgG (H&L) anitbody is suitable for immunoblotting (western or dot blot), ELISA, immunoelectron microscopy and immunochemistry as well as other antibody based enzymatic assays requiring lot-to-lot consistency.
Catalog Number: CA603-105-002
Supplier: Rockland Immunochemical


Description: This product has been assayed against 1.0 µg of Human IgG in a standard capture ELISA using pNPP p-nitrophenyl phosphate as a substrate for 30 minutes at room temperature.
Catalog Number: CA609-4518
Supplier: Rockland Immunochemical


Description: Anti-HUMAN IgG (H&L) (Sheep) Antibody is suitable for immunoblotting (western or dot blot), ELISA, immunoperoxidase electron microscopy and immunochemistry as well as other peroxidase-antibody based enzymatic assays requiring lot-to-lot consistency.
Catalog Number: CA609-6502
Supplier: Rockland Immunochemical


Description: Widely found in natural waters, sulfate may be at high levels in mine drainage
Catalog Number: CA11014-208
Supplier: Hach


Description: Anti-Monkey IgM (mu chain) Antibody is suitable for immunoblotting (western or dot blot), ELISA, immunoperoxidase electron microscopy and immunochemistry as well as other peroxidase-antibody based enzymatic assays requiring lot-to-lot consistency.
Catalog Number: CA617-105-007
Supplier: Rockland Immunochemical


Description: Trypsin is a proteolytic enzyme used to detach adherent cell from culture vessel surfaces. Typical use includes removing adherent cells from a culture surface. The concentration of trypsin necessary to dislodge cells from their substrate is dependent primarily on the cell type and the age of the culture.
Catalog Number: 10128-794
Supplier: QUALITY BIOLOGICAL, INC.

Description: Hollow cathode lamps produced by Photron are designed and manufactured to achieve all of the following fundamental requirements for a spectral line source: Intense emission of resonance (ground state derived) lines. Narrow line width, for maximum sensitivity and linearity. Minimal spectral interference from continuum emission, present in the cathode. Rapid warm up to produce stable long term light emission. Noise free operation. Long running life and a 5 year shelf life. Cathode materials and geometry achieve a combination of spectral purity and a suitable sputtering rate. (A high sputtering rate will give high intensity at the expense of lamp life, sensitivity and linearity).
Catalog Number: CA11017-978
Supplier: PHOTRON CA


Description: PPM1D (Wip) is a serine/threonine phosphatase implicated in cell cycle control, spermatogenesis, and lymphoid cell function. The predicted 605-amino acid PPM1D protein contains 2 putative nuclear localization signals and 3 regions conserved in serine/threonine PP2C phosphatases, as well as characteristics of a type 2C phosphatase, including magnesium dependence and relative insensitivity to okadaic acid. PPM1D expression is induced in response to ionizing radiation in a p53-dependent manner. The accumulation of PPM1D mRNA following ionizing radiation is rapid and transient, and PPM1D protein is localized to the nucleus. PPM1D may contribute to growth inhibitory pathways activated in response to DNA damage in a p53-dependent manner. PPM1D inhibits phosphorylation of the p38 mitogen-activated (MAP)kinase protein. Through p38 MAPK, PPM1D modulates the CDKN2A tumor-suppressor locus. This gene is located in a chromosomal region known to be amplified in breast cancer, (located at 17q22-q23), is amplified in human breast tumor cell lines and in approximately 11% of primary breast tumors, and appears to lead to cell transformation by abrogating p53 tumor suppressor activity. Inactivation of the p38 MAPK through PPM1D overexpression resulting from PPM1D amplification may contributes to the development of human cancers by suppressing p53 activation. PPM1D null mice have increased susceptibility to pathogens and reduced male fertility and longevity.
Function : Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins.
Subunit : Interacts with CHEK1 and CHEK2; dephosphorylates them.
Similarity : Belongs to the PP2C family. Contains 1 PP2C-like domain.
Catalog Number: 77439-764
Supplier: Bioss


Description: Produced through a multi-stage process that includes delipidation, salt fractionation, ion-exchange chromatography, gel filtration, and affinity chromatography. No contaminating proteins are observed when assayed at a protein concentration of 20mg/mL against anti-whole serum or anti-fragment specific antisera. All immunoglobulin fragments are prepared from highly purified, whole molecules subject to enzymatic digestion.
Catalog Number: CA009-0502
Supplier: Rockland Immunochemical


Description: Bst 3.0 DNA Polymerase is an in silico designed homologue of Bacillus stearothermophilus DNA Polymerase I, Large Fragment engineered for improved isothermal amplification performance and increased reverse transcription activity
Catalog Number: 102969-114
Supplier: New England Biolabs (NEB)

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