Description: FUNCTION: Involved in redox regulation of the cell. Can reduce hydrogen peroxide and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. SUBUNIT: Homotetramer. May interact with HTR2A. SUBCELLULAR LOCATION: Cytoplasm. Lysosome. Also found in lung secretory organelles. MISCELLANEOUS: The active site is the redox-active Cys-47 oxidized to Cys-SOH. Cys-SOH may rapidly react with a Cys-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin . MISCELLANEOUS: Irreversibly inactivated by overoxidation of Cys-47 (to Cys-SO(3)H) upon oxidative stress. SIMILARITY: Belongs to the ahpC/TSA family. Rehydrin subfamily.

Catalog Number: 10782-746

Supplier: Biosensis

Sale

Description: Tertiapin Q (TPN Q) shows the same channel-blocking activity as the bee venom peptide tertiapin (N-1745), but increased stability due to the exchange of Met¹³ by Gln.

Catalog Number: N-2005.0500BA

Supplier: Bachem Americas

Sale

Description: The major physiological roles of Arg-Vasopressin are regulation of water balance in animals (antidiuretic action) and contraction of arterioles (vasopressor action). CAS number (argipressin acetate): 129979-57-3.

Catalog Number: H-1780.0001BA

Supplier: Bachem Americas

Sale

Description: Melanin-concentrating hormone (MCH), originally isolated from salmon pituitary glands, has also been found in the mammalian CNS. In lower vertebrates, salmon MCH alters pigmentation by inducing melanosome aggregation within melanocytes of teleost fish, whereas it causes melanosome dispersion in amphibians and reptiles. The biological role of MCH in higher vertebrates, however, is not yet fully understood, but it may function as a neuromodulator and hypophysiotropic agent in the secretion of α-MSH, ACTH, and GH.

Catalog Number: H-6408.0005BA

Supplier: Bachem Americas

Sale

Description: (Arg)9 is a cell-permeable peptide used for drug delivery. It can traverse the plasma membrane of eukaryotic cells, and can be easily conjugated to the molecule to be internalized
Sequence:C(Npys)RRRRRRRRR-NH2
MW:1680.1 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: 103006-408

Supplier: Anaspec Inc

Sale

Description: 250mg CAS: 88440-55-5 C7H13N3O4S FW: 235.26

Catalog Number: H-1552.0250BA

Supplier: Bachem Americas

Sale

Description: The MDC gene is one of several Cys-Cys (CC) cytokine genes which are clustered on the q arm of chromosome 16.

Catalog Number: 10098-246

Supplier: Prosci

Sale

Description: CAS Number: 207121-46-8
MDL Number: MFCD00150051
Molecular Formula: C3H7NO2S
Molecular Weight: 157.61
Purity/Analysis Method: >99.0% (T)
Form: Crystal
Specific rotation [a]20/D: -6 deg (C=8, 1mol/L HCl)

Catalog Number: TCC1329-005G

Supplier: TCI America

SDS Certificates Sale

Description: CAS Number: 384842-24-4 MDL Number: MFCD10565627 Molecular Formula: C27H35P Molecular Weight: 390.55 Purity/Analysis Method: <gt/>90.0% (HPLC) Form: Crystal Melting point (°C): 130

Catalog Number: TCC2981-1G

Supplier: TCI America

SDS Sale

Description: PRL2915, Cpa-D-Cys-Pal-D-Trp-Lys-Tle-Cys-Nal-amide, highly potent human somatostatin subtype 2 receptor (hsst2) antagonist with a Ki of 12 nM. Ki values for the other subtypes were >1000 nM for hsst1, 100 ± 57 nM for hsst3, 895 nM for hsst4, and 520 nM for hsst5, respectively. No agonist activity was found when tested alone at concentrations up to 10 µM. In a rat pituitary growth hormone in vitro antagonist assay versus somatostatin-14 (1nM) the somatostatin octapeptide analog PRL2915 exhibited an IC₅₀ value of 1.8 nM.

Catalog Number: H-6056.1000BA

Supplier: Bachem Americas

Sale

Description: Human Cystatin C(Cys-C) ELISA Kit

Catalog Number: 76704-708

Supplier: AFG Bioscience

Sale

Description: Rabbit Cystatin C (Cys-C) ELISA Kit

Catalog Number: 77525-818

Supplier: AFG Bioscience

Sale

Description: Cy™ fluorescent amidites for incorporation of Cy3, Cy3.5, Cy5, Cy5.5 fluorescent dyes at any position in an oligonucleotide during synthesis.

Catalog Number: CA95040-124L

Supplier: Cytiva

Sale

Description: 1G (Disulfide bond) CAS: 62130-80-7 C24H30N4O6S2 FW: 534.66

Catalog Number: G-1825.0250BA

Supplier: Bachem Americas

Sale

Description: L-Cystine dimethyl ester dihydrochloride, 98%

Catalog Number: AAH63234-03

Supplier: Thermo Scientific Chemicals

SDS Certificates Sale

Description: TP1 Antibody: Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes. Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TP1). Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death. High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression levels of TP1 do not correlate with malignancy. At least two isoforms of TP1 are known to exist.

Catalog Number: 89415-446

Supplier: Prosci

Sale