You Searched For: RITA


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Catalog Number: (10168-000)
Supplier: Genetex
Description: Mouse Monoclonal antibody to Importin beta-1


Catalog Number: (10106-552)
Supplier: Prosci
Description: C2ta is essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. C2ta may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter


Supplier: Enzo Life Sciences
Description: K+ channel blocker

Catalog Number: (470337-152)
Supplier: 3-D Molecular Designs
Description: Model the scientific process


Supplier: AAT BIOQUEST INC
Description: PI Brite™ is a propidium iodide (PI) analog developed by AAT Bioquest to improve the brightness and fixability of propidium iodide in cells.

Catalog Number: (10480-202)
Supplier: Bioss
Description: May forms part of a complex of membrane proteins attached to acetylcholinesterase (AChE).Tissue specificity:Ubiquitous. Widely expressed in brain.


Catalog Number: (10480-196)
Supplier: Bioss
Description: May forms part of a complex of membrane proteins attached to acetylcholinesterase (AChE).Tissue specificity:Ubiquitous. Widely expressed in brain.


Catalog Number: (97051-378)
Supplier: MicroSolv Technology Corp
Description: Beta Tool™ is a pair of precision, high grade pliers and can be used as needle nose pliers or as a tubing straightener.


Catalog Number: (10083-684)
Supplier: Proteintech
Description: Primary microcdphaly refers to the clinical finding of a head circumference less than 3 standard deviations(SD) below the age- and sex-related mean, present at birth. MCPH1, the fisrt gene identified as causative for primary microcephaly, encodes a multifunctional protein that notably is linked to DNA damage checkpoint, DNA repair by homologous recombination and DNA transcription. MCPH1 is associated with premature chromosome condensation in particular. There are two mainly isoforms encoded by MCPH1 gene, isoform1(~100kd) and isoform2(~66kd)


Catalog Number: (10402-882)
Supplier: Bioss
Description: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


Catalog Number: (10366-106)
Supplier: Bioss
Description: IKK beta (I-Kappa-B kinase-beta) is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK beta activity can also be regulated by MEKK1.


Supplier: Medicom
Description: Sponges intended for medical purposes, such as to be placed directly on a patient’s wound to absorb exudates.

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Supplier: Ricca Chemical
Description: 0.0575 (+/-0.00001) Molar. (21.404 g EDTA-Na2*2H2O per liter). Container: Plastic.
Catalog Number: (89415-904)
Supplier: Prosci
Description: Bit1 Antibody: Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading. Anoikis is the molecular mechanism of apoptosis induced by integrin detachment. Bit1 (Bcl-2 inhibitor of transcription 1) was recently identified as being involved in this process. Bit1 is a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis where it forms a complex with AES, a small Groucho/transducin-like enhancer of split (TLE) protein and induces caspase-independent apoptosis. Both AES and TLE proteins are transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination. It has been suggested that Bit1-AES complexes turn off a survival-promoting gene transcription program controlled by TLE. Interestingly, apoptosis of cells transfected with Bit1 and AES could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.


Catalog Number: (10163-172)
Supplier: Genetex
Description: Rabbit polyclonal antibody to CIITA


Catalog Number: (10480-192)
Supplier: Bioss
Description: May forms part of a complex of membrane proteins attached to acetylcholinesterase (AChE).Tissue specificity:Ubiquitous. Widely expressed in brain.


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