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Image Unavailable-102996-792

390 MMP FRET Substrate IV, Mca-DNP

Catalog Number: (102996-792)
Supplier: Anaspec Inc
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This substrate is readily hydrolyzed by MMP-8, 9 and collagenase-3 (MMP-13), Abs/Em = 325/393 nm. The hydrolysis is inhibited in a 1:1 stoichiometric fashion by the tissue inhibitors of metalloproteinases, TIMP-1, TIMP-2, and TIMP-3.
Sequence:Mca-P-Cha-G-Nva-HA-Dap(Dnp)-NH2
MW:1100.2 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-103008-974

SensoLyte® Green Pin1 Assay Kit (Fluorimetric), AnaSpec Inc.

Catalog Number: (103008-974)
Supplier: Anaspec Inc
Description: Peptidyl-prolyl isomerase (PPIase) Pin1 catalyzes cis/trans isomerization of the phospho-Serine/Threonine-Proline peptide bonds
Image Unavailable-G-3050.0001BA

H-Pro-Phe-OH

Supplier: Bachem Americas
Description: See also E-2410, Suc-Pro-OH, the product familiy 'Antihypertensive Peptides' and the subfamily 'Bradykinin-Potentiating Peptides (BPP)'.

Image Unavailable-102996-784

490 MMP FRET Substrate III, DABCYL-EDANS

Catalog Number: (102996-784)
Supplier: Anaspec Inc
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide has an optimized sequence for MMP-7, with the cleavage occuring at the Ala-Leu bond. The substrate is used for high throughput screening of MMP-7 inhibitors. Abs/Em = 340/490 nm.
Sequence:DABCYL-RPLALWRS-EDANS
MW:1497.8 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-75791-722

Mouse Recombinant Kallikrein 7

Catalog Number: (75791-722)
Supplier: Prosci
Description: Kallikrein7, also named as stratum corneum chymotryptic enzyme (SCCE), is a secreted protein of the Kallikrein-related peptidase (KLK) family. This family contains fifteen homologous secreted serine endopeptidases and plays a significant role in various physiological processes, including skin desquamation, semen liquefaction, neural plasticity, and body fluid homeostasis. In skin KLK5, KLK 7 and KLK14 are able to degrade corneodesmosomes, which leads to desquamation of skin surface cells. KLK activation is believed to be mediated through highly organized proteolytic cascades, regulated through a series of feedback loops, inhibitors, auto-degradation and internal cleavages. Studies have shown that one potential physiological activator for KLK7 is KLK5. Along with KLK14, these three kallikreins form a proteolytic cascade in the stratum corneum. KLK7 is primarily expressed in the skin but is also detected at relatively high levels in esophagus, heart, liver, central nervous system, kidney, pancreas, mammary and salivary glands.
Product Image-89156-500

DPPIV Drug Discovery Kit, Enzo Life Sciences

Catalog Number: (89156-500)
Supplier: Enzo Life Sciences
Description: The DPPIV Drug Discovery Kit is a complete assay system designed to screen DPPIV inhibitors, a potential therapeutic target, providing enough material to perform at least 96 assays.
Image Unavailable-CA60801-172

Endopeptidase Lys-C (from Achromobacter lyticus)

Catalog Number: (CA60801-172)
Supplier: MilliporeSigma
Description: Endopeptidase Lys-C (from Achromobacter lyticus)
Product Image-77517-368

Human ASTL (Astacin Like Metallo Endopeptidase) ELISA Kit

Catalog Number: (77517-368)
Supplier: AFG Bioscience
Description: Human ASTL (Astacin Like Metallo Endopeptidase) ELISA Kit
Image Unavailable-I-1840.0050BA

Z-Val-Ala-Asn-AMC

Supplier: Bachem Americas
Description: Substrate for the determination of a new cysteine endopeptidase which is required for antigen processing. Z-VAN-AMC has been used as a fluorogenic substrate for porcine asparaginyl endopeptidase (AEP, legumain).

Product Image-76703-988

Human Procollagen C Endopeptidase Enhancer 2 (PCOLCE2) ELISA Kit

Catalog Number: (76703-988)
Supplier: AFG Bioscience
Description: Human Procollagen C Endopeptidase Enhancer 2 (PCOLCE2) ELISA Kit
Image Unavailable-77537-956

Human Astacin Like Metallo Endopeptidase (ASTL) ELISA Kit

Catalog Number: (77537-956)
Supplier: Bioss
Description: Human Astacin Like Metallo Endopeptidase (ASTL) ELISA Kit

New Product


Product Image-76700-364

Mouse Procollagen C-endopeptidase Enhancer 2(PCOLCE2) ELISA Kit

Catalog Number: (76700-364)
Supplier: AFG Bioscience
Description: Mouse Procollagen C-endopeptidase Enhancer 2(PCOLCE2) ELISA Kit
Product Image-CA89168-036

Immobilized Papain

Catalog Number: (CA89168-036)
Supplier: G-Biosciences
Description: Papain is a cysteine protease enzyme (EC 3.4.22.2) that has the endopeptidase activity to cleave immunoglobulin G molecules in the hinge region.

SDS


Image Unavailable-10165-928

Anti-PCOLCE2 Rabbit Polyclonal Antibody

Catalog Number: (10165-928)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to PCOLCE2 (procollagen C-endopeptidase enhancer 2)
Image Unavailable-CA82022-518

SG-Chymotrypsin™

Catalog Number: (CA82022-518)
Supplier: G-Biosciences
Description: SG-Chymotrypsin™ is a serine endopeptidase, which predominantly cleaves peptide bonds on the carboxy side of tyrosine, phenylalanine and tryptophan
Product Image-76710-350

Human Procollagen C Endopeptidase Enhancer 1 (PCOLCE) ELISA Kit

Catalog Number: (76710-350)
Supplier: AFG Bioscience
Description: Human Procollagen C Endopeptidase Enhancer 1 (PCOLCE) ELISA Kit
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