You Searched For: Pifithrin-\\\\u03B1+(cyclic)+hydrobromide

Catalog Number: (CA95043-882)

Supplier: Enzo Life Sciences

Description: Neutralizing buffer for low pH solutions, for use with cyclic nucleotide and isoprostane kits.

Catalog Number: (CAPI26101)

Supplier: Thermo Scientific

Description: Pierce™ Traut's Reagent (2-Iminothiolane or 2-IT) is a cyclic thioimidate compound for thiolation (sulfhydryl addition)

SDS Certificates

Catalog Number: (89356-822)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to PDE1A (calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A)

Catalog Number: (75879-250)

Supplier: Greiner Bio-One

Description: Due to their excellent optical, chemical, and physical properties, cycloolefin microplates have become increasingly popular in research and high-throughput screening.

Catalog Number: (77437-672)

Supplier: Bioss

Description: Buffers cytosolic calcium. May stimulate a membrane Ca(²⁺)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.

Catalog Number: (77436-886)

Supplier: Bioss

Description: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.

Supplier: Thermo Scientific Chemicals

Description: Protein kinase inhibitor. Inhibits cyclic nucleotide dependent protein kinase (PKA) and protein kinase C

Certificates

Catalog Number: (10092-014)

Supplier: Proteintech

Description: PDE7B(cAMP-specific 3',5'-cyclic phosphodiesterase 7B) belongs to the cyclic nucleotide phosphodiesterase family and PDE7 subfamily,which regulate intracellular levels of cAMP and cGMP, cyclic nucleotides that play important roles as second messengers in multiple physiologic processes. PDE7B gene is expressed predominantly in the brain and in a number of other tissues including liver, heart, thyroid glands, and skeletal muscle, but not expressed in blood leukocytes .

Catalog Number: (103389-204)

Supplier: Eagle Biosciences

Description: Immunoscan RA-CCPlus test detects IgG antibodies to Cyclic Citrullinated Peptides in human sera.

Supplier: Bachem Americas

Description: Urotensin II is a vasoactive somatostatin-like cyclic peptide, which has long been regarded as a peptide exclusively produced by the urophysis of teleost fish. U-II has also been cloned from man. It was found to be the most potent mammalian vasoconstrictor identified so far. Furthermore, as urotensin II immunoreactivity was also found within central nervous system and endocrine tissues, it may have additional activities.

Catalog Number: (10084-946)

Supplier: Proteintech

Description: CNP(2',3'-cyclic-nucleotide 3'-phosphodiesterase) belongs to the cyclic nucleotide phosphodiesterase family. It plays an essential role in axonal survival but not in myelin assembly, coupling oligodendroglial functions in axonal support and myelination. This protein has 2 isoforms produced by alternative splicing.

Catalog Number: (CA71003-228)

Supplier: G-Biosciences

Description: G-Biosciences' Iminobiotin Resin consists of iminobiotin, a cyclic guanido analog of biotin, covalently coupled to 6% crosslinked agarose

SDS

Catalog Number: (CAPIPA5-18473)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with human and rat based on sequence homology. This gene is a member of the type IV, cyclic AMP family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Supplier: New England Biolabs (NEB)

Description: Ribonuclease If (RNase If) is an RNA endonuclease which will cleave at all RNA dinucleotide bonds leaving a 5´ hydroxyl and 2´, 3´ cyclic monophosphate

Supplier: Anaspec Inc

Description: Somatostatin [SST, GHIH (growth hormone-inhibiting hormone) or SRIF (somatotropin release-inhibiting factor)] is a cyclic peptide hormone existing as two isoforms and produced in the pancreas islet, GI tract and the central nervous system. Tetradecapeptide Somatostatin-14 (SRIF-14, the originally identified somatostatin) and the 28-amino acid Somatostatin-28 (SRIF-28) have similar biological activities but differ in their potency. Somatostatins regulate the endocrine system: they inhibit the release of growth hormone in contrast to Growth Hormone Factor (GRF), which stimulates the release of growth hormone. They also inhibit the release of prolactin and thyrotropin, peptide hormones from the pituitary gland and glucagon and insulin from the pancreas. They control the secretion of gut hormones and function as neurotransmitters.
Sequence: AGCKNFFWKTFTSC (Disulfide bridge: 3-14)
MW: 1637.9 Da
% Peak area by HPLC: 95
Storage condition: -20° C

Catalog Number: (89367-374)

Supplier: Genetex

Description: The cyclic monophosphate nucleotides (cyclic adenosine monophosphate [cAMP] and cyclic guanosine monophosphate [cGMP]) are found ubiquitously in mammalian cells and act as second messenger transducers to effect the intracellular actions of a variety of G protein coupled receptors (GPCRs) for hormones, cytokines, and neurotransmitters. Cyclic nucleotides are important intracellular second messengers which play important role in a variety of signal transduction process. The cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. One of the many phosphodiesterases that compartmentalized and hydrolyze cGMP in various tissues is phosphodiesterase type 5A. The cGMP is involved in nitric oxide signaling as well as cell signaling associated with natriuretic peptides and gulanylins. Some of the intracellular biding cites for the cGMP include cyclic nucleotide gated ion channels, cGMP dependent protein kinases, and cyclic GMP biding phosphodiesterases (cGB PDEs). The cGB PDEs include PDE2, PDE3, PDE5, PDE5 and PDE10; the members of these families contain various structural and functional motifs that are conserved. Most of these proteins contain dimmeric subunits that contain a highly conserved cGMP binding site and a phosphodiesterase catalytic site.