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Anti-Mesothelin Rabbit Monoclonal Antibody [clone: YP158]

Catalog Number: (CA76634-884)
Supplier: Diagnostic Biosystems
Description: Mesothelin is a glycocylphosphotidylianositol-linked cell-surface glycoprotein, which is present on the surface of normal mesothelium and is overexpressed in many patients with epithelial ovarian cancer and malignant mesotheliomas.
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Anti-Alk/p80 Mouse Monoclonal Antibody [clone: 4A4]

Supplier: Diagnostic Biosystems
Description: Anaplastic lymphoma kinase (ALK) known as ALK tyrosine kinase receptor or CD246, is a tyrosine kinase receptor. ALK is an important biomarker for diagnosis of non-­‐small cell lung cancer (NSCLC).

Image Unavailable-CA76634-888

Anti-PRAME Rabbit Monoclonal Antibody [clone: EPR20330]

Catalog Number: (CA76634-888)
Supplier: Diagnostic Biosystems
Description: PRAME (Preferentially expressed Antigen in Melanoma) is a tumorassociated antigen and is a member of the family of cancer testis antigens (CTA). PRAME is expressed in malignant cells, including leukaemias, Hodgkin's lymphoma, breast cancer, and primary and metastatic melanomas. PRAME has low or no expression in normal tissues except for in testis, ovary, placenta, adrenals and endometrium.
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Anti-PRAME Rabbit Monoclonal Antibody [clone: EPR20330]

Supplier: Diagnostic Biosystems
Description: PRAME (Preferentially expressed Antigen in Melanoma) is a tumorassociated antigen and is a member of the family of cancer testis antigens (CTA). PRAME is expressed in malignant cells, including leukaemias, Hodgkin's lymphoma, breast cancer, and primary and metastatic melanomas. PRAME has low or no expression in normal tissues except for in testis, ovary, placenta, adrenals and endometrium.

Image Unavailable-CA76634-768

Anti-Mammoglobin A Rabbit Monoclonal Antibody [clone: EPR 9092]

Supplier: Diagnostic Biosystems
Description: The mammaglobin gene was first identified using a differential screening approach directed at the isolation of novel, human breast cancer-associated genes. Mammaglobin-A is highly overexpressed in breast cancer cell lines and primary breast tumors. This pattern of expression is restricted to mammary epithelium and metastatic breast tumors. Thus, mammaglobin-A-specific T cell immune responses may provide an important approach for the design of breast cancer-specific immunotherapy.

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Anti-Mammaglobin A Rabbit Monoclonal Antibody [clone: EPR 9092]

Catalog Number: (CA76634-866)
Supplier: Diagnostic Biosystems
Description: The mammaglobin gene was first identified using a differential screening approach directed at the isolation of novel, human breast cancer-associated genes. Mammaglobin-A is highly overexpressed in breast cancer cell lines and primary breast tumors. This pattern of expression is restricted to mammary epithelium and metastatic breast tumors. Thus, mammaglobin-A-specific T cell immune responses may provide an important approach for the design of breast cancer-specific immunotherapy.
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Anti-Retinoblastoma protein Mouse Monoclonal Antibody [clone: 1F8]

Catalog Number: (CA76634-360)
Supplier: Diagnostic Biosystems
Description: This antibody recognizes human retinoblastoma gene protein. Rb gene, a prototype of tumor suppressor genes, has been associated with development and/or progression of bladder cancer as well as sarcoma and small cell lung cancer. Functional Rb gene loss has been reported to occur in bladder cancer and osteosarcoma. A significantly poorer tumor-free survival rate was noted for those patients who had a tumor with an altered Rb protein with or without vascular invasion.
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Anti-Cyclin D1 Rabbit Monoclonal Antibody [clone: EP12]

Supplier: Diagnostic Biosystems
Description: Cyclin D1 belongs to the Cyclin D family. Cyclin D1 is required for the cell cycle G1/S transition. Amplification or overexpression of Cyclin D1 plays a pivotal role in the development of various human cancers including breast cancer, colon cancer, melanoma, prostate cancer and lymphoma. It is useful to differentiate mantle cell lymphoma from small cleaved cell lymphoma. Rabbit monoclonal antibodies to Cyclin D1 showed the highest sensitivity to detect this antigen in formalin fixed paraffin embedded tissue as compared to several other clones.

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Anti-Cyclin D1 Rabbit Monoclonal Antibody [clone: SP4]

Supplier: Diagnostic Biosystems
Description: Cyclin D1 belongs to the Cyclin D family. Cyclin D1 is required for the cell cycle G1/S transition. Amplification or overexpression of Cyclin D1 plays a pivotal role in the development of various human cancers including breast cancer, colon cancer, melanoma, prostate cancer and lymphoma. It is useful to differentiate mantle cell lymphoma from small cleaved cell lymphoma. Rabbit monoclonal antibodies to Cyclin D1 showed the highest sensitivity to detect this antigen in formalin fixed paraffin embedded tissue as compared to several other clones.

Image Unavailable-CA76634-864

Anti-ERG Rabbit Monoclonal Antibody [clone: EP111]

Catalog Number: (CA76634-864)
Supplier: Diagnostic Biosystems
Description: ERG, the ETS related gene, belongs to the ETS family that plays important roles in cell development, differentiation, proliferation, apoptosis and tissue remodeling. The ERG antibody identifies endothelial cells, lymphocytes and prostate cancer cells.
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Anti-Retinoblastoma Protein Mouse Monoclonal Antibody [clone: 1F8]

Supplier: Diagnostic Biosystems
Description: This antibody recognizes human retinoblastoma gene protein. Rb gene, a prototype of tumor suppressor genes, has been associated with development and/or progression of bladder cancer as well as sarcoma and small cell lung cancer. Functional Rb gene loss has been reported to occur in bladder cancer and osteosarcoma. A significantly poorer tumor-free survival rate was noted for those patients who had a tumor with an altered Rb protein with or without vascular invasion.

Image Unavailable-CA76634-544

Anti-ALK/p80 Mouse Monoclonal Antibody [clone: 4A4]

Catalog Number: (CA76634-544)
Supplier: Diagnostic Biosystems
Description: Anaplastic lymphoma kinase (ALK) known as ALK tyrosine kinase receptor or CD246, is a tyrosine kinase receptor. ALK is an important biomarker for diagnosis of non-­‐small cell lung cancer (NSCLC).
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Anti-CA125 Mouse Monoclonal Antibody [clone: OV185:1]

Supplier: Diagnostic Biosystems
Description: This antibody reacts specifically with CA 125 ovarian cancer antigen. Several studies have shown that CA 125 is a useful tumor marker for ovarian epithelial malignancies. However, CA 125 has been described in other neoplasms such as seminal vesicle and anaplastic lymphomas.

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Anti-CA 19-9 Mouse Monoclonal Antibody [clone: C241:5:1:4]

Supplier: Diagnostic Biosystems
Description: This antibody reacts specifically with Sialyl Lewis A and recognizes an epitope being designated CA 19-9. It does not cross-react with Lewis A and Lewis B. CA 19-9 has been shown to be useful marker in the diagnosis and management of gastrointestinal cancers.

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Anti-CA 19-9 Mouse Monoclonal Antibody [clone: C241:5:1:4]

Catalog Number: (CA76634-546)
Supplier: Diagnostic Biosystems
Description: This antibody reacts specifically with sialyl Lewisa and recognizes an epitope being designated CA 19-9. It does not cross-reacts with Lewisa and Lewisb. CA 19-9 has been shown to be useful marker in the diagnosis and management of gastrointestinal cancers.
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Anti-Cyclin D1 Rabbit Monoclonal Antibody [clone: EP12]

Catalog Number: (CA76634-882)
Supplier: Diagnostic Biosystems
Description: Cyclin D1 belongs to the Cyclin D family. Cyclin D1 is required for the cell cycle G1/S transition. Amplification or overexpression of Cyclin D1 plays a pivotal role in the development of various human cancers including breast cancer, colon cancer, melanoma, prostate cancer and lymphoma. It is useful to differentiate mantle cell lymphoma from small cleaved cell lymphoma. Rabbit monoclonal antibodies to Cyclin D1 showed the highest sensitivity to detect this antigen in formalin fixed paraffin embedded tissue as compared to several other clones.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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