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Image Unavailable-CAPIPA5-14264

Anti-TMPRSS2 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-14264)
Supplier: Thermo Scientific
Description: TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.
Image Unavailable-10667-292

Anti-ATAD2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10667-292)
Supplier: Bioss
Description: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
Image Unavailable-10388-022

Anti-ZNF772 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10388-022)
Supplier: Bioss
Description: Mammaglobin B may bind androgens and other steroids, it may also bind estramustine, a chemotherapeutic agent used for prostate cancer. It may be under transcriptional regulation of steroid hormones.
Product Image-10086-312

Anti-EGFR Rabbit Polyclonal Antibody

Catalog Number: (10086-312)
Supplier: Proteintech
Description: ERBB1, also mamed as EGFR, is a receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. ERBB1 is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with C-SRC and CTNNB1/beta-catenin. Isoform 2/truncated isoform of ERBB1 may act as an antagonist. EGFR is associated with lung cancer. The antibody is specific to isoform1.
Product Image-89417-536

Anti-SCRN3 Rabbit Polyclonal Antibody

Catalog Number: (89417-536)
Supplier: Prosci
Description: SCRN3 Antibody: SCRN3 is a member of the secernin family of proteins which includes the homologous SCRN1, a protein that was first identified as being involved in the regulation of exocytosis from peritoneal mast cells. Little is known of SCRN3, but studies have shown that SCRN1 may possess epitopes that function as tumor-associated antigens in gastric cancers and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN3 may also be involved in protein secretion or the regulation of cell growth.
Product Image-10751-548

Anti-C9orf116 Rabbit Polyclonal Antibody

Catalog Number: (10751-548)
Supplier: Prosci
Description: PIERCE1 Antibody: PIERCE1, also known as C9orf116, is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.
Image Unavailable-10487-482

Anti-DCAF12 Rabbit Polyclonal Antibody

Catalog Number: (10487-482)
Supplier: Bioss
Description: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR40A (WD-repeat-containing protein 40A), also known as DDB1- CUL4-associated factor 12, is a 453 amino acid cytoplasmic protein that contains four WD-repeats. WDR40A is highly expressed in some cancer cell lines, lung cancer tissues and normal testis. A probable substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex, WRD40A is suggested to interact with DDB1. WDR40A is encoded by a gene mapping to human chromosome 9p13.3. Human chromosome 9 houses over 900 genes and comprises nearly 4% of the human genome.
Image Unavailable-10785-882

Accessories for PrimaCell™, Human Thyroid Carcinoma Cell Culture Kit, CHI Scientific

Supplier: CHI Scientific
Description: Primacell* 17 Kit Human Cancer OptiTDS*17, Tissue Dissociation System, Stability, package should be stored at -20 degree C, and effective up to 4 months

Product Image-CA89429-348

Sabouraud Dextrose (SabDex) Agar Blue, Hardy Diagnostics

Catalog Number: (CA89429-348)
Supplier: HARDY DIAGNOSTICS CA
Description: Sabouraud Dextrose (SabDex) Agar, Blue, not for human diagnostic use, 26ml fill, 15x100mm plate, order by the package of 10, by Hardy Diagnostics

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Product Image-89417-096

Anti-PALB2 Rabbit Polyclonal Antibody

Catalog Number: (89417-096)
Supplier: Prosci
Description: PALB2 Antibody: The breast cancer early onset proteins BRCA1 and BRCA2 are central to the repair of DNA damage by homologous recombination and are strongly associated with inherited breast and ovarian cancer. The protein PALB2 is required for the localization of BRCA2 to sites of DNA damage and like BRCA1 and 2 is a breast cancer susceptibility gene. PALB2 is thought to function through directly binding to BRCA1, which allows the PALB2 protein to organize BRCA2 and the recombinase RAD51 at the site of DNA damage. Analysis of the BRCA1-PALB2-BRCA2-RAD51network may allow predictions to be made of the responsiveness of a particular tumor to therapeutic treatments. At least four isoforms of PALB2 are known to exist.
Product Image-10798-452

Human Recombinant TNF alpha (from HEK293 Cells)

Catalog Number: (10798-452)
Supplier: Prosci
Description: Tumor necrosis factor alpha (TNF?) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNF? is in the regulation of immune cells. TNF? is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNF? production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNF? is used as an immunostimulant under the INN tasonermin. TNF? can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
Image Unavailable-76119-074

Anti-SSX5 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76119-074)
Supplier: Bioss
Description: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.
Image Unavailable-89156-572

Sulindac Sulfide ≥99% (by TLC)

Supplier: Enzo Life Sciences
Description: Active metabolite of sulindac. Inhibits cyclooxygenase. More selective for PGHS-1 (ID50=0.5 µM) over PGHS-2 (ID50=14 µM). Induces apoptosis by a cyclooxygenase-independent mechanism. Inhibits colorectal cancer growth and γ-secretase. NF-κB inhibitor. Inhibits Ras signaling.

Product Image-10749-956

Anti-STEAP4 Rabbit Polyclonal Antibody

Catalog Number: (10749-956)
Supplier: Prosci
Description: STEAP4 Antibody: The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.
Image Unavailable-10415-000

Anti-KIT Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10415-000)
Supplier: Bioss
Description: c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.
Product Image-10107-496

Anti-KDM4D Rabbit Polyclonal Antibody

Catalog Number: (10107-496)
Supplier: Prosci
Description: JMJD2D belongs to JMJD2 family that is consist of four cancer-associated genes
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