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Image Unavailable-10476-676

Anti-CCDC136 Rabbit Polyclonal Antibody

Catalog Number: (10476-676)
Supplier: Bioss
Description: Expressed in gastric tissues. Down-regulated in gastric cancer.
Product Image-10751-108

Anti-PLAC1 Rabbit Polyclonal Antibody

Catalog Number: (10751-108)
Supplier: Prosci
Description: PLAC1 Antibody: PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.
Product Image-10065-298

Phosphate Buffer, Hardy Diagnostics

Catalog Number: (10065-298)
Supplier: Hardy Diagnostics
Description: For the preparation of specimens for AFB culture and other applications.

SDS Product available on GSA Advantage®


Product Image-76024-202

ZING Green Safety Eco GHS Sign, DANGER, Blank, Cancer

Supplier: ZING Enterprises
Description: The signs measures 10''x14'' and is available in three eco-friendly materials.

Environmentally Preferable

Image Unavailable-75794-012

Human Recombinant Angiocidin (from E. coli)

Catalog Number: (75794-012)
Supplier: Prosci
Description: Angiocidin shows sequence similarity with proteasome components and is also being referred to as 26A proteasome regulatory subunit S5A. Angiocidin shows both matrix and cytoplasmic distribution. It binds to thrombospondin-1 and alpha2beta1 integrin, and it inhibits tumor progression and angiogenesis. Angiocidin is expressed in various types of cancer, such as hepatocellular carcinoma, prostate, lung, bladder, and melanoma cancers.
Product Image-76299-194

Pyridoxine Y Medium, CRITERION™ Dehydrated Culture Media, Hardy Diagnostics

Supplier: Hardy Diagnostics
Description: Hardy Diagnostics CRITERION™ Pyridoxine Y Medium recommended for use in determining pyridoxine concentration via the microbiological assay technique.

Product available on GSA Advantage®

Product Image-10090-268

Anti-MLH1 Rabbit Polyclonal Antibody

Catalog Number: (10090-268)
Supplier: Proteintech
Description: MLH1, also named as COCA2, belongs to the DNA mismatch repair mutL/hexB family. It heterodimerizes with PMS2 to form MutL alpha which is a component of the post-replicative DNA mismatch repair system (MMR). MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. MLH1 also implicated in DNA damage signaling, a process which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. MLH1 heterodimerizes with MLH3 to form MutL gamma which plays a role in meiosis. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2). Defects in MLH1 are a cause of mismatch repair cancer syndrome (MMRCS). Defects in MLH1 are a cause of Muir-Torre syndrome (MTS). Defects in MLH1 are a cause of susceptibility to endometrial cancer . This antibody is special to MLH1.
Product Image-89416-782

Anti-DACT3 Rabbit Polyclonal Antibody

Catalog Number: (89416-782)
Supplier: Prosci
Description: Dact3 Antibody: The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases. Many members of this pathway are also expressed in the postnatal tissues such as brain. One such protein is Dact3, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling. Dact3 is expressed in the ventral region of maturing somites, limb bud and branchial arch mesenchyme, embryonic CNS, and the adult brain. Recent evidence shows that Dact3 acts as a negative regulator Wnt/beta-catenin signaling that is repressed at the transcriptional level in colorectal cancer and this repression is associated with bivalent histone modifications. This repression can be reversed by pharmacological agents that targets both histone methylation and deacetylation, suggesting that Dact3 may be a potential target for therapeutic treatment of this cancer. At least three isoforms of Dact3 are known to exist.
Product Image-CA52428-870

R2A Agar, Hardy Diagnostics

Catalog Number: (CA52428-870)
Supplier: HARDY DIAGNOSTICS CA
Description: R2A Agar, 18ml fill, 20x125mm tube deep, order by the package of 20, by Hardy Diagnostics.

Certificates


Image Unavailable-10664-538

Anti-BRMS1 Rabbit Polyclonal Antibody

Catalog Number: (10664-538)
Supplier: Bioss
Description: Breast cancer metastasis-suppressor 1 (BRMS1) is 246 amino acid protein that acts as a mediator of metastasis suppression in several types of cancer including ovarian, lung, bladder, and murine mammary. BRMS1 mRNA is expressed in various tissues, including ovary, prostate, testis, and colon, but the protein is primarily detected in term placenta. BRMS1 suppresses metastasis without inhibiting tumorigenicity by modifying several metastasis-associated phenotypes. BRMS1 may participate in transcriptional regulation by binding to the mSin3/histone deacetylase complex. The expression of BRMS1 in certain cells increases connexin Cx43 expression and reduces connexin Cx32 expression. This produces a gap junction that increases intercellular communication, similar to those found in normal breast tissue. BRMS1 is stabilized by Hsp90 and may inhibit NF-â…¹B activity.
Product Image-470160-250

GPI Anatomicals® Stomach Cancer Model

Catalog Number: (470160-250)
Supplier: GPI ANATOMICALS
Description: This is full size cut-away section of stomach shows a developed carcinoma tumor.

Small Business Enterprise


Image Unavailable-52197-454

Accessories for Micro-Osmometer, Advanced Instruments

Supplier: Advanced Instruments
Description: 5 value. For use with all osmometers.

Certificates

Product Image-10784-672

PrimaCell™, Human Bladder Tumor Cell Culture Kit, CHI Scientific

Catalog Number: (10784-672)
Supplier: CHI Scientific
Description: The PrimaCell™ system has been developed for the acquisition and growth of primary cells from a variety of different tissue types. Each PrimaCell™ kit has been optimized for each cell type to produce 4-7 times the number of primary cells obtained from published literature protocols. Each kit comes with 100 ml of tissue washing medium, our optimized tissue dissociation system OptiTDS™, 500 ml of growth medium, and enough growth supplements and serum to add to the supplied medium. Kits that require a Fibroblast control system also come with our FibrOut™ kit (added to the growth medium) which reduces or eliminates Fibroblast growth after 2-3 cell growth cycles.
Product Image-10784-682

PrimaCell™, Human Breast Tumor Cell Culture Kit, CHI Scientific

Catalog Number: (10784-682)
Supplier: CHI Scientific
Description: The PrimaCell™ system has been developed for the acquisition and growth of primary cells from a variety of different tissue types. Each PrimaCell™ kit has been optimized for each cell type to produce 4-7 times the number of primary cells obtained from published literature protocols. Each kit comes with 100 ml of tissue washing medium, our optimized tissue dissociation system OptiTDS™, 500 ml of growth medium, and enough growth supplements and serum to add to the supplied medium. Kits that require a Fibroblast control system also come with our FibrOut™ kit (added to the growth medium) which reduces or eliminates Fibroblast growth after 2-3 cell growth cycles.
Image Unavailable-76118-044

Anti-Hepsin Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76118-044)
Supplier: Bioss
Description: This gene encodes a type II transmembrane serine protease. The encoded protein has an extracellular region that consists of two domains, a catalytic serine protease domain and a non-catalytic scavenger receptor cysteine-rich domain. This protein may be involved in diverse cellular functions including blood coagulation, maintenance of cell morphology and the growth and progression of certain cancers, particularly prostate cancer. Alternative splicing results in multiple transcript variants.
Image Unavailable-10340-616

Anti-ZNF217 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10340-616)
Supplier: Bioss
Description: ZNF217 (Zinc-finger protein 217) is a Kruppel-like zinc-finger protein which functions as a transcriptional repressor protein and forms a complex with a number of proteins including CoREST, BHC110/LSD1, HDAC2 and CtBP1. ZNF217 has been shown to repress E-cadherin promoter activity. ZNF217 is overexpressed in a number of cancers including breast and ovarian. ZNF217 and its associated proteins have been implicated in a novel pathway that is involved in cancer progression.
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