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Sulindac sulfone ≥94% (by HPLC)

Supplier: Enzo Life Sciences
Description: Induces apoptosis but does not inhibit cyclooxygenase. Inhibits growth and induces apoptosis in human cancer cell lines. Metabolite of Sulindac.

Product Image-76299-194

Pyridoxine Y Medium, CRITERION™ Dehydrated Culture Media, Hardy Diagnostics

Supplier: Hardy Diagnostics
Description: Hardy Diagnostics CRITERION™ Pyridoxine Y Medium recommended for use in determining pyridoxine concentration via the microbiological assay technique.

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Image Unavailable-10454-008

Anti-ZNF146 Rabbit Polyclonal Antibody

Catalog Number: (10454-008)
Supplier: Bioss
Description: Tissue specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.
Product Image-CA52428-870

R2A Agar, Hardy Diagnostics

Catalog Number: (CA52428-870)
Supplier: HARDY DIAGNOSTICS CA
Description: R2A Agar, 18ml fill, 20x125mm tube deep, order by the package of 20, by Hardy Diagnostics.

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Image Unavailable-10434-482

Anti-HPN Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10434-482)
Supplier: Bioss
Description: This gene encodes a type II transmembrane serine protease. The encoded protein has an extracellular region that consists of two domains, a catalytic serine protease domain and a non-catalytic scavenger receptor cysteine-rich domain. This protein may be involved in diverse cellular functions including blood coagulation, maintenance of cell morphology and the growth and progression of certain cancers, particularly prostate cancer. Alternative splicing results in multiple transcript variants.
Product Image-89416-344

Anti-STEAP1 Rabbit Polyclonal Antibody

Catalog Number: (89416-344)
Supplier: Prosci
Description: STEAP1 Antibody: The six-transmembrane epithelial antigen of prostate 1 (STEAP1) was the first member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. The normal function of STEAP is still uncertain; unlike other members of the STEAP family, STEAP1 does not promote iron or copper reduction or uptake and lacks the FNO-like reductase domain critical for activity. However, its expression is highly increased in multiple cancer cell lines, including prostate, bladder, colon, and ovarian cancers. Supporting this is evidence that STEAP1 peptides can be used to stimulate CD8+ T cells from healthy donors, enabling them to recognize STEAP1-positive human tumor cells, suggesting that STEAP1 may a potential target for cancer immunotherapy. At least three isoforms of STEAP1 are known to exist.
Product Image-10090-268

Anti-MLH1 Rabbit Polyclonal Antibody

Catalog Number: (10090-268)
Supplier: Proteintech
Description: MLH1, also named as COCA2, belongs to the DNA mismatch repair mutL/hexB family. It heterodimerizes with PMS2 to form MutL alpha which is a component of the post-replicative DNA mismatch repair system (MMR). MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. MLH1 also implicated in DNA damage signaling, a process which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. MLH1 heterodimerizes with MLH3 to form MutL gamma which plays a role in meiosis. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2). Defects in MLH1 are a cause of mismatch repair cancer syndrome (MMRCS). Defects in MLH1 are a cause of Muir-Torre syndrome (MTS). Defects in MLH1 are a cause of susceptibility to endometrial cancer . This antibody is special to MLH1.
Image Unavailable-10430-926

Anti-TUSC1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10430-926)
Supplier: Bioss
Description: This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.
Image Unavailable-52197-454

Accessories for Micro-Osmometer, Advanced Instruments

Supplier: Advanced Instruments
Description: 5 value. For use with all osmometers.

Certificates

Product Image-76308-452

Orum International TRIO.BAS™ Air Sampler Calibration Services, Hardy Diagnostics

Supplier: Hardy Diagnostics
Description: Hardy Diagnostics is the sole North American distributor of the Orum TRIO.BAS™ Microbial Air Samplers.

Image Unavailable-75789-342

Human Recombinant Kallikrein 13 (from Cells)

Catalog Number: (75789-342)
Supplier: Prosci
Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
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Human Recombinant Kallikrein 10 (from Cells)

Catalog Number: (75789-338)
Supplier: Prosci
Description: Kallikreins are a subgroup of Serine Proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Image Unavailable-75789-352

Human Recombinant Kallikrein 8 (from Cells)

Catalog Number: (75789-352)
Supplier: Prosci
Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Image Unavailable-75789-344

Human Recombinant Kallikrein 4 (from Cells)

Catalog Number: (75789-344)
Supplier: Prosci
Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Product Image-89416-782

Anti-DACT3 Rabbit Polyclonal Antibody

Catalog Number: (89416-782)
Supplier: Prosci
Description: Dact3 Antibody: The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases. Many members of this pathway are also expressed in the postnatal tissues such as brain. One such protein is Dact3, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling. Dact3 is expressed in the ventral region of maturing somites, limb bud and branchial arch mesenchyme, embryonic CNS, and the adult brain. Recent evidence shows that Dact3 acts as a negative regulator Wnt/beta-catenin signaling that is repressed at the transcriptional level in colorectal cancer and this repression is associated with bivalent histone modifications. This repression can be reversed by pharmacological agents that targets both histone methylation and deacetylation, suggesting that Dact3 may be a potential target for therapeutic treatment of this cancer. At least three isoforms of Dact3 are known to exist.
Product Image-470160-250

GPI Anatomicals® Stomach Cancer Model

Catalog Number: (470160-250)
Supplier: GPI ANATOMICALS
Description: This is full size cut-away section of stomach shows a developed carcinoma tumor.

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