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Image Unavailable-10472-598

Anti-DUSP26 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10472-598)
Supplier: Bioss
Description: Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).Tissue specificity:Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer.
Image Unavailable-10348-636

Anti-SCGB2A2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10348-636)
Supplier: Bioss
Description: Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.
Image Unavailable-10348-644

Anti-SCGB2A2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10348-644)
Supplier: Bioss
Description: Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.
Product Image-76334-640

Viral Transport Medium (VTM), Hardy Diagnostics

Catalog Number: (76334-640)
Supplier: Hardy Diagnostics
Description: Hardy Diagnostics Viral Transport Medium is recommended for the collection and transport of clinical specimens for the recovery of viral agents.

Certificates


Product Image-10449-420

Anti-LDOC1 Rabbit Polyclonal Antibody

Catalog Number: (10449-420)
Supplier: Bioss
Description: May have an important role in the development and/or progression of some cancers.
Image Unavailable-75790-830

Human Recombinant Astrocytic Phosphoprotein PEA-15 (from E. coli)

Catalog Number: (75790-830)
Supplier: Prosci
Description: Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis and cancer progression. PEA15 is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. PEA15 blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. PEA15 also inhibits RPS6KA3 activities by holding it in the cytoplasm. In addition, PEA15 inhibits both TNFRSF6 and TNFRSF1A mediated CASP8 activity and apoptosis. At present, PEA15 expression is also a significant prognostic marker in ovarian cancer.
Product Image-10086-312

Anti-EGFR Rabbit Polyclonal Antibody

Catalog Number: (10086-312)
Supplier: Proteintech
Description: ERBB1, also mamed as EGFR, is a receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. ERBB1 is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with C-SRC and CTNNB1/beta-catenin. Isoform 2/truncated isoform of ERBB1 may act as an antagonist. EGFR is associated with lung cancer. The antibody is specific to isoform1.
Product Image-89417-536

Anti-SCRN3 Rabbit Polyclonal Antibody

Catalog Number: (89417-536)
Supplier: Prosci
Description: SCRN3 Antibody: SCRN3 is a member of the secernin family of proteins which includes the homologous SCRN1, a protein that was first identified as being involved in the regulation of exocytosis from peritoneal mast cells. Little is known of SCRN3, but studies have shown that SCRN1 may possess epitopes that function as tumor-associated antigens in gastric cancers and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN3 may also be involved in protein secretion or the regulation of cell growth.
Image Unavailable-77436-882

Anti-ABCG2 Rabbit Polyclonal Antibody

Catalog Number: (77436-882)
Supplier: Bioss
Description: An ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side population cells, which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.
Image Unavailable-76081-400

Anti-PBOV1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76081-400)
Supplier: Bioss
Description: This gene is overexpressed in prostate and breast cancer.
Product Image-16149-159

Screw Caps for Screw Neck Diagnostic Bottles, WHEATON®

Supplier: DWK Life Sciences (KIMBLE)
Description: Polypropylene closures with gray bromobutyl / 50 stoppers.

Certificates Small Business Enterprise

Product Image-16059-660

Nalgene® Diagnostic Bottles, with Closure, Natural PPCO, Bulk Pack, Thermo Scientific

Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Nalgene PPCO diagnostic bottles with polypropylene closures are used in test kits and many small-volume applications.

Certificates Environmentally Preferable

Image Unavailable-CAPIPA5-18119

Anti-SART1 Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18119)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with bovine, mouse and rat based on sequence homology. This gene encodes two proteins, the SART1protein expressed in the nucleus of the majority of proliferating cells, and the SART1protein expressed in the cytosol of epithelial cancers. The SART1protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.
Image Unavailable-12000-632

Accessories for Advanced® Multi-Sample Osmometer, Model 2020, Advanced Instruments

Supplier: Advanced Instruments
Description: 20uL. For use with osmometers.

Certificates

Image Unavailable-10346-928

Anti-BRINP1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10346-928)
Supplier: Bioss
Description: Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.
Image Unavailable-10476-690

Anti-CCDC136 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10476-690)
Supplier: Bioss
Description: Expressed in gastric tissues. Down-regulated in gastric cancer.
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