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Accessories for PrimaCell™, Human Skin Cancer Cell Culture Kit, CHI Scientific

Supplier: CHI Scientific
Description: Kit, Primacell* 15 Human Cancer OptiTDS*15: Tissue Dissociation System, Stability/Storage: Stable at the room temperature, stored at -20 deg C

Image Unavailable-10450-034

Anti-PCANAP2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10450-034)
Supplier: Bioss
Description: PSA, prostate specific antigen, is the classic indicator for transformed pro-state tissue; however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia. Prostein, also designated Prostate cancer-associated protein 6, is a prostate-specific, 553 amino acid transmembrane protein that is upregulated by androgens. It is considered a marker for prostate cells since it is expressed in all prostatic glandular cells as well as in normal and cancerous prostate tissues. Since it is able to elicit a tumor-directed cytotoxic T cell response, Prostein may be used as a target for the development of PSA- and T cell-based therapeutic strategies for prostate cancer.
Image Unavailable-75974-050

Anti-Small Cell Lung Cancer Mouse Monoclonal Antibody (CF405S) [clone: MOC-52]

Supplier: Biotium
Description: This MAb reacts with a membrane-associated protein present in normal and malignant neuroendocrine tissues including small cell lung cancer (SCLC). It stains neural and a variable number of endocrine tissues and in the lung it reacts preferentially with SCLC and carcinoids. Its epitope is destroyed during formalin fixation. This antibody was categorized during the First International Workshop on Small Cell Lung Cancer Antigens held in London in April 1987. There are two major types of Lung Carcinoma: non-small cell, which accounts for 80% of all cases; and small cell, which accounts for roughly 20% of all lung cancers reported. The lung continues to be a customary place for cancer migration from tumors elsewhere in the body. Treatment depends on the specific cell type of the cancer, level of progression and status of the individual patient.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Image Unavailable-10453-764

Anti-TULP2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10453-764)
Supplier: Bioss
Description: TULP2 is a member of a family of tubby-like (TULP) proteins which share a conserved C terminal region of approximately 200 amino acid residues. It is strongly expressed in testis and is expressed in the retina. It is also expressed in cancer cell lines.
Product Image-10751-022

Anti-SCRN1 Rabbit Polyclonal Antibody

Catalog Number: (10751-022)
Supplier: Prosci
Description: SCRN1 Antibody: SCRN1 was first identified as a cytosolic protein that is involved in the regulation of exocytosis from peritoneal mast cells. More recent studies have shown that SCRN1 expression is upregulated in gastric cancer cell lines and may possess epitopes that could function as tumor-associated antigens, potentially providing targets for cancer vaccines in the treatment of gastric cancers. Another report indicates that decreased expression of SCRN1 via RNAi expression resulted in significantly lower rates of cell growth in colorectal cancer cell lines, and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN1 may also be involved in the regulation of cell growth and might be useful as a prognostic tool.
Image Unavailable-10459-492

Anti-PAGE4 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10459-492)
Supplier: Bioss
Description: PAGE4 belongs to the GAGE family of genes which are expressed in a variety of tumors and in some fetal and reproductive tissues. PAGE4 is strongly expressed in prostate and prostate cancer, but is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer.
Image Unavailable-10459-484

Anti-PAGE4 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10459-484)
Supplier: Bioss
Description: PAGE4 belongs to the GAGE family of genes which are expressed in a variety of tumors and in some fetal and reproductive tissues. PAGE4 is strongly expressed in prostate and prostate cancer, but is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer.
Image Unavailable-10459-486

Anti-PAGE4 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10459-486)
Supplier: Bioss
Description: PAGE4 belongs to the GAGE family of genes which are expressed in a variety of tumors and in some fetal and reproductive tissues. PAGE4 is strongly expressed in prostate and prostate cancer, but is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer.
Image Unavailable-77440-558

Anti-CT45A Rabbit Polyclonal Antibody

Catalog Number: (77440-558)
Supplier: Bioss
Description: Cancer/testis antigen family 45 is testis specific and expressed in cancer cell lines.
Product Image-77751-060

Human Recombinant AMPHIREGULIN (from E. coli)

Supplier: VWR International
Description: Amphiregulin (AR) is a member of the epidermal growth factor (EGF) family. AR is an autocrine growth factor and functions to regulate cell proliferation and survival through binding the EGF receptor (EGFR). AR promotes the proliferation of neural stem cells and epithelial cells, including keratinocytes and mammary epithelium. Up-regulated at puberty, AR promotes ductal outgrowth and mammary branching. In the liver, AR functions as a mitogen and prevents hepatocyte apoptosis. In a cancer context, AR protects against human adenocarcinoma apoptosis, promotes tumor cell growth, and functions as an oncogenic factor in the Hippo pathway. AR levels are increased in the brain following stress events, such as inflammation, ischemia, and hypoxia.

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Product Image-470119-038

3B Scientific® Skin Cancer Model

Catalog Number: (470119-038)
Supplier: American 3B Scientific
Description: This 3B Scientific® Skin Pathology model shows healthy skin and 5 different stages of malignant melanoma on the front and back, enlarged 8 times. In the top view of the skin cancer model, the individual stages of externally visible skin changes are shown, allowing for an assessment according to the 'ABCDE' criteria.
Image Unavailable-10785-848

Accessories for PrimaCell™, Human Esophageal Fibroblast Cancer Primary Cell, Cell Culture Kit, CHI Scientific

Supplier: CHI Scientific
Description: Primacell* 7 Kit Human Cancer OptiTDS*7, Tissue Dissociation System, Stability, package should be stored at -20 degree C, and effective up to 4 months

Product Image-76699-962

Human Receptor-binding Cancer Antigen expressed on SiSo cell 1(RCAS1) ELISA Kit

Catalog Number: (76699-962)
Supplier: AFG Bioscience
Description: Human Receptor-binding Cancer Antigen expressed on SiSo cell 1(RCAS1) ELISA Kit
Image Unavailable-10387-994

Anti-MRGBP Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10387-994)
Supplier: Bioss
Description: Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.
Product Image-10100-354

Anti-TUSC1 Rabbit Polyclonal Antibody

Catalog Number: (10100-354)
Supplier: Prosci
Description: Tusc1 gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.
Product Image-10785-826

PrimaCell™, Human Esophageal Tumor Cell Culture Kit, CHI Scientific

Catalog Number: (10785-826)
Supplier: CHI Scientific
Description: The PrimaCell™ system has been developed for the acquisition and growth of primary cells from a variety of different tissue types. Each PrimaCell™ kit has been optimized for each cell type to produce 4-7 times the number of primary cells obtained from published literature protocols. Each kit comes with 100 ml of tissue washing medium, our optimized tissue dissociation system OptiTDS™, 500 ml of growth medium, and enough growth supplements and serum to add to the supplied medium. Kits that require a Fibroblast control system also come with our FibrOut™ kit (added to the growth medium) which reduces or eliminates Fibroblast growth after 2-3 cell growth cycles.
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