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Product Image-76733-774

Rat PDE5A/PDE5 ELISA Kit

Catalog Number: (76733-774)
Supplier: ANTIBODIES.COM LLC
Description: Rat PDE5A/PDE5 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of rat PDE5A/PDE5 in serum, plasma, tissue homogenates, and other biological fluids.
Product Image-76737-866

Mouse PDE5A/PDE5 ELISA Kit

Catalog Number: (76737-866)
Supplier: ANTIBODIES.COM LLC
Description: Mouse PDE5A/PDE5 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse PDE5A/PDE5 in serum, plasma, tissue homogenates, and other biological fluids.
Product Image-76739-832

Human PDE5A/PDE5 ELISA Kit

Catalog Number: (76739-832)
Supplier: ANTIBODIES.COM LLC
Description: Human PDE5A/PDE5 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human PDE5A/PDE5 in serum, plasma, tissue homogenates, and other biological fluids.
Image Unavailable-TCE1134-25G

PDE5-IN-7 ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: 5-(2-Ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone, Purity: >98.0%(HPLC)(T), CAS Number: 139756-21-1, Molecular Formula: C17H20N4O2, MW: 312.37, Size: 5G

Image Unavailable-89367-374

Anti-PDE5A Rabbit Polyclonal Antibody

Catalog Number: (89367-374)
Supplier: Genetex
Description: The cyclic monophosphate nucleotides (cyclic adenosine monophosphate [cAMP] and cyclic guanosine monophosphate [cGMP]) are found ubiquitously in mammalian cells and act as second messenger transducers to effect the intracellular actions of a variety of G protein coupled receptors (GPCRs) for hormones, cytokines, and neurotransmitters. Cyclic nucleotides are important intracellular second messengers which play important role in a variety of signal transduction process. The cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. One of the many phosphodiesterases that compartmentalized and hydrolyze cGMP in various tissues is phosphodiesterase type 5A. The cGMP is involved in nitric oxide signaling as well as cell signaling associated with natriuretic peptides and gulanylins. Some of the intracellular biding cites for the cGMP include cyclic nucleotide gated ion channels, cGMP dependent protein kinases, and cyclic GMP biding phosphodiesterases (cGB PDEs). The cGB PDEs include PDE2, PDE3, PDE5, PDE5 and PDE10; the members of these families contain various structural and functional motifs that are conserved. Most of these proteins contain dimmeric subunits that contain a highly conserved cGMP binding site and a phosphodiesterase catalytic site.
Image Unavailable-10165-630

Anti-PDE5A Rabbit Polyclonal Antibody

Catalog Number: (10165-630)
Supplier: Genetex
Description: Rabbit polyclonal antibody to PDE5 (phospho Ser92)
Image Unavailable-89367-362

Anti-PDE11A Rabbit Polyclonal Antibody

Catalog Number: (89367-362)
Supplier: Genetex
Description: One of the many phosphodiesterases that compartmentalize and hydrolyze cAMP and cGMP into AMP and GMP is Phosphodiesterase type 11. The human PDE11A contains an open reading frame encoding a 490 amino acid protein (55-56 kDa). The PDE11A has an N-terminus GAF domain homologous to other signaling molecule as found in PDE2, PDE5, PDE6, PDE10, which potentially represents an allosteric cGMP and other small signaling molecules. PDE11A hydrolyzes both cGMP and cAMP; it is sensitive to non-selective PDE inhibitor IBMX as well as zaprinast and dipyrimadole inhibitors that are generally selective for cGMP-specific enzymes. PDE11A expression is diverse and is found in high levels in skeletal muscle, prostate, kidney, liver, pituitary and testis.
Image Unavailable-89367-360

Anti-PDE11A Rabbit Polyclonal Antibody

Catalog Number: (89367-360)
Supplier: Genetex
Description: One of the many phosphodiesterases that compartmentalize and hydrolyze cAMP and cGMP into AMP and GMP is Phosphodiesterase type 11. The human PDE11A contains an open reading frame encoding a 490 amino acid protein (55-56 kDa). The PDE11A has an N-terminus GAF domain homologous to other signaling molecule as found in PDE2, PDE5, PDE6, PDE10, which potentially represents an allosteric cGMP and other small signaling molecules. PDE11A hydrolyzes both cGMP and cAMP; it is sensitive to non-selective PDE inhibitor IBMX as well as zaprinast and dipyrimadole inhibitors that are generally selective for cGMP-specific enzymes. PDE11A expression is diverse and is found in high levels in skeletal muscle, prostate, kidney, liver, pituitary and testis.
Image Unavailable-77122-874

PDE5A Peptide

Catalog Number: (77122-874)
Supplier: Prosci
Description: PDE5A Peptide
Image Unavailable-76759-426

Anti-PDE5A Rabbit Polyclonal Antibody

Catalog Number: (76759-426)
Supplier: Prosci
Description: Anti-PDE5A Rabbit Polyclonal Antibody
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