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Catalog Number: (10101-088)
Supplier: Prosci
Description: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The KCNAB1 gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily.


Catalog Number: (CA76420-660)
Supplier: Eppendorf
Description: Mix samples completely and reliably with the Eppendorf® MixMate. 96 and 384-well plates and reaction tubes are mixed by the 2DMix-Control technology even at the microliter scale. The additional vortex function has a 2 s run timer allowing processing your next sample without restarting.


Supplier: Scientific Industries
Description: Vortex Genie® Mixers are available in multiple models and with a vast array of available platforms and accessories.

Catalog Number: (10101-102)
Supplier: Prosci
Description: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Four sequence-related potassium channel genes, shaker, shaw, shab, and shal, have been identified in Drosophila, and each has been shown to have human homolog (s). KCNA10 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP.


Catalog Number: (MSPP-780841006)
Supplier: STEMCELL Technologies
Description: Interleukin-8 (IL-8) is a member of the CXC subfamily of chemokines and is produced by leukocytic cells (monocytes, T cells, neutrophils, and natural killer cells) and non-leukocytic somatic cells (endothelial cells, fibroblasts, and epithelial cells), with the most prominent source being monocytes and macrophages. Its production is induced by inflammatory stimuli, such as IL-1. IL-8, also known as CXCL8, activates neutrophils inducing chemotaxis, exocytosis, and the respiratory burst (Baggiolini and Clark-Lewis; Mukaida). IL-8 is considered one of the most potent neutrophil chemoattractants in inflammation and binds to two different chemokine receptors on leukocytes: the G protein-coupled receptors CXCR1 and CXCR2 (Hoffmann <i>et al.</i>; de Oliveira <i>et al.</i>). IL-8 has angiogenic effects on human intestinal microvascular endothelial cells in vitro that are mediated by CXCR2 (Heidemann <i>et al.</i>). IL-8 is reported to promote breast cancer progression by increasing cell invasion, angiogenesis, and metastasis and has been reported to be involved in regulating breast cancer stem-like cells (Singh <i>et al.</i>). IL-8 also has proangiogenic properties in inflammatory diseases of the conjunctiva, cornea, iris, retina, and orbit (Ghasemi <i>et al.</i>). It was also shown that a major T cell effector function in human newborns is IL-8 production, which has the potential to activate antimicrobial neutrophils and gamma/delta T cells (Gibbons <i>et al.</i>). A variety of human pathogens, such as HIV and Mycobacterium tuberculosis, have been shown to induce IL-8 production by monocytes and macrophages (Friedland <i>et al.</i>; Meddows-Taylor <i>et al.</i>).

New Product


Catalog Number: (10088-752)
Supplier: Proteintech
Description: KCNA4, also named as KCNA4L, HBK4, HUKII, HK1 and HPCN2, belongs to the potassium channel family and A (Shaker) subfamily. KCN4 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The antibody is specific to KCN4.


Supplier: Caron Products
Description: Caron's Reach-in CO<sub>2</sub> Incubators are optimized for suspension and scale up cell culture applications that require agitation or shaking so nutrients are distributed throughout the culture media. Ready to accommodate shakers inside, these CO<sub>2</sub> incubators provide optimum environmental conditions for precise and reproducible results.

Environmentally Preferable Small Business Enterprise CSA Certified Product available on GSA Advantage®

Catalog Number: (89063-384)
Supplier: Ace Glass
Description: This borosilicate glass vessel, offset adapter, coupling and modified top bottle clamp are used with shaker type Parr Hydrogenation/Gas Apparatus I (89058-912) to allow temperature measurement while connected to hydrogen source

Small Business Enterprise Product available on GSA Advantage®


Catalog Number: (10809-770)
Supplier: Brady Worldwide
Description: Kit includes: 6.5 Gallon bucket (same as our SKA-BKT), 1 - 2lb shaker base neutralizer, 10 Universal Pads, 2 Socs, 2 Bags, Goggles, Gloves, Tyvek Suit


Supplier: Thermo Fisher Scientific
Description: Made of lightweight, clear PETG plastic, these flasks are ideal for shaker and suspension cell culture, as well as media preparation or storage.
Catalog Number: (76333-470)
Supplier: Chemglass
Description: Sticky pads is an ideal alternative to flask clamps for securing vessels to a shaker platform. The mat is designed for use with containers with a flat wide base. It is ideal for containers such as bottles and dishes that cannot be held with traditional flask clamps. With shake flasks the pad can be used at speeds up 200 or 300 rpm (see chart), from −30 to 70 °C. It can be regenerated for reuse by simply washing it with mild detergent and water.


Catalog Number: (77775-244)
Supplier: Brady Worldwide
Description: <p>The acid neutralizer is used to solidify a wide range of base spills.</p>

New Product


Catalog Number: (10101-208)
Supplier: Prosci
Description: This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product.


Supplier: Thermo Fisher Scientific
Description: Made of lightweight, clear PETG plastic, these flasks are ideal for shaker and suspension cell culture, as well as media preparation or storage.
Supplier: Chemglass
Description: These flasks have six bottom baffles to maximize oxygen transfer for bacterial, yeast and other cultures that require large amounts of oxygen for optimal growth.

Small Business Enterprise

Catalog Number: (10101-642)
Supplier: Prosci
Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.


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