You Searched For: Nocodazole


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Supplier: Enzo Life Sciences
Description: Microtubule inhibitor

Catalog Number: (10751-686)
Supplier: Prosci
Description: ZF21 Antibody: ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.


Catalog Number: (CA80058-500)
Supplier: MilliporeSigma
Description: NOCODAZOLE 10 MG

Catalog Number: (89165-878)
Supplier: Enzo Life Sciences
Description: Suitable for DNA studies in live, permeabilized and fixed cells for normal cell lines and cell lines exhibiting multiple ploidy levels.

SDS


Catalog Number: (89165-890)
Supplier: Enzo Life Sciences
Description: Cell Cycle Results Independent of Incubation Time, Temperature, Dye and Cell Concentrations

SDS


Catalog Number: (89298-166)
Supplier: Genetex
Description: Goat polyclonal antibody to UBE2C / UBCH10


Catalog Number: (10113-008)
Supplier: Prosci
Description: Polyclonal, Host: Goat, Species: Human, Immunogen: UBCH10 antibody was raised against a 13 amino acid synthetic peptide near the C-Terminus of UBCH10, Application: ELISA, WB


Catalog Number: (89359-238)
Supplier: Genetex
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fibre is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. Covalent modifications of the canonical core histones, including acetylation, phosphorylation, methylation, and monoubiquitination, are used to mark nucleosomes to create chromatin domains with a range of functions. The information encoded by the modifications can contribute to the formation and/or maintenance of transcriptionally active and inactive chromatin in response to various signalling pathways. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones. Phosphorylation of histone H3, referred to as the nucleosomal response, is localized to a small fraction of highly acetylated H3 and occurs primarily in response to mitogenic and stress stimuli.2, 3, 9-12 Phosphorylation of histone H3 on S10 is tightly correlated with chromosome condensation during both mitosis and meiosis. Phosphorylation at this site is also directly correlated with the induction of immediate-early genes such as c-jun, c-fos, and c-myc.


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