You Searched For: Ionomycin+calcium+salt

Description: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.

Catalog Number: 10481-412

Supplier: Bioss

Sale

Description: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.

Catalog Number: 10481-402

Supplier: Bioss

Sale

Description: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.

Catalog Number: 76109-024

Supplier: Bioss

Sale

Description: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.

Catalog Number: 10481-408

Supplier: Bioss

Sale

Description: Sodium taurocholate hydrate 96%

Catalog Number: CAAAA18346-06

Supplier: Thermo Scientific Chemicals

Certificates Sale

Description: Ferrozine mono-sodium salt hydrate 97%

Catalog Number: CAAAB24066-03

Supplier: Thermo Scientific Chemicals

Certificates Sale

Description: Zwitterionic detergent ideal for solubilization of membrane proteins, analytical, diagnostic, chromatography, electrophoresis work, and enzymology and immunology applications.
Suitable for Molecular Biology

Catalog Number: CAEM3050

Supplier: MilliporeSigma

SDS Certificates Sale

Description: Thermo Scientific Pierce Sulfo-LC-SPDP is a water-soluble, long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteines.

Catalog Number: CAPI21650

Supplier: Thermo Scientific

SDS Certificates Sale

Description: Ideal for enzyme-antibody crosslinking.

Catalog Number: CA82022-426

Supplier: G-Biosciences

Sale

Description: CAS Number: 92921-24-9
MDL Number: MFCD00054978
Molecular Formula: C16H18N2O9S
Molecular Weight: 436.37
Form: Crystal
Color: White
Storage Temperature: <0°C

Catalog Number: TCS0883-20MG

Supplier: TCI America

SDS Certificates Sale

Description: CAS Number: 577-11-7
MDL Number: MFCD00012455
Molecular Formula: C20H38O7S
Molecular Weight: 444.56
Purity/Analysis Method: >95.0% (T)
Form: Spongy Solid
Color: White
Melting point (°C): 179

Catalog Number: TCS0139-025G

Supplier: TCI America

SDS Certificates Sale

Description: Sequence: Fmoc-Met(O₂)-OH

Catalog Number: B-1905.0005BA

Supplier: Bachem Americas

Sale

Description: Ideal for enzyme-antibody crosslinking.

Catalog Number: CA82022-814

Supplier: G-Biosciences

Sale

Description: [for Biochemical Research]
CAS Number: 82692-88-4
MDL Number: MFCD00063425
Molecular Formula: C11H17NO6S
Molecular Weight: 313.30
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Color: White
Storage Temperature: 0-10°C

Catalog Number: TCS0827-200MG

Supplier: TCI America

SDS Sale

Description: SMCC, Water-Soluble, a water-soluble derivative of SMCC.

Catalog Number: CA80057-544

Supplier: MilliporeSigma

SDS Certificates Sale

Description: CAS Number: 13177-41-8
MDL Number: MFCD00043218
Molecular Formula: C23H49NO3S
Molecular Weight: 419.71
Purity/Analysis Method: >97.0% (N)
Form: Crystal
Melting point (°C): 260
Flash Point (°C): 110

Catalog Number: TCO0261-025G

Supplier: TCI America

SDS Certificates Sale