You Searched For: N-Benzoyl-L-tyrosine

Catalog Number: (10070-440)

Supplier: Prosci

Description: Plays an important role in the physiology of adrenergic neurons.

Catalog Number: (102996-570)

Supplier: Anaspec Inc

Description: The native peptide,RRLIEDAEYAARG (cat# 22581), is derived from pp60src, and considered to be a generic substrate for various protein tyrosine kinases. The fluorescent and biotinylated peptides are used to design a variety of assays for PTKs.
Sequence:RRLIEDAE-pY-AARG
MW:1599.7 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (10416-000)

Supplier: Bioss

Description: The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.

Catalog Number: (10416-004)

Supplier: Bioss

Description: The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.

Catalog Number: (77516-008)

Supplier: AFG Bioscience

Description: Human TNK2 (Tyrosine Kinase, Non Receptor 2) ELISA Kit

Catalog Number: (B-3795.0001BA)

Supplier: Bachem Americas

Description: Besides a large selection of tyrosine derivatives, Bachem offers derivatives of O-alkylated tyrosines, thyronine, phosphotyrosine and sulfotyrosine. Bachem additionally offers H-[¹⁵N]Tyr-OH, E-3245.

Catalog Number: (77510-906)

Supplier: AFG Bioscience

Description: Human JAK2 (Tyrosine-Protein Kinase JAK2) ELISA Kit

Catalog Number: (10416-010)

Supplier: Bioss

Description: The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.

Catalog Number: (76709-454)

Supplier: AFG Bioscience

Description: Human AXL Receptor Tyrosine kinase (AXL) ELISA Kit

Catalog Number: (77524-634)

Supplier: AFG Bioscience

Description: Mouse TH (Tyrosine Hydroxylase) ELISA Kit

Catalog Number: (76715-188)

Supplier: AFG Bioscience

Description: Human Leukocyte Tyrosine Kinase Receptor (LTK) ELISA Kit

Catalog Number: (10782-480)

Supplier: Biosensis

Description: Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine, epinephrine and norepinephrine. Therefore the regulation of the TH enzyme represents the central means for controlling the synthesis of these important catecholamines. FUNCTION: Plays an important role in the physiology of adrenergic neurons. CATALYTIC ACTIVITY: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydrobiopterin. COFACTOR: Fe(2+) ion. ENZYME REGULATION: Phosphorylation leads to an increase in the catalytic activity. PATHWAY: Catecholamine biosynthesis; first step. SUBUNIT: Homotetramer. PTM: In vitro, phosphorylation of Ser-19 increases the rate of Ser-40 phosphorylation, which results in enzyme opening and activation. SIMILARITY: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. The presence of different DNA sequences at the TH locus confers susceptibility to various disorders of the brain including manic-depression and schizophrenia. Parkinson's disease is also considered a TH deficiency as low dopamine levels are a consistent neurochemical abnormality.

Catalog Number: (102997-478)

Supplier: Anaspec Inc

Description: These peptides are potential substrates for EGFR protein tyrosine kinases. The fluorescent and biotinylated peptides are used to design assays for CaMKs.
Sequence:ADEYLIPQQ
MW:1076.1 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (89149-324)

Supplier: Enzo Life Sciences

Description: Tyrosine kinase inhibitor

Supplier: Abcam

Description: Alexa Fluor® 568 Rabbit monoclonal [EP1532Y] to Tyrosine Hydroxylase - Neuronal Marker.

New Product

Catalog Number: (76708-436)

Supplier: AFG Bioscience

Description: Human FMS-like tyrosine kinase 3(Flt3) ELISA Kit