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Image Unavailable-76100-942

Anti-Group I mGLUR Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76100-942)
Supplier: Bioss
Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions.
Product Image-10075-602

Anti-GRM5 Rabbit Polyclonal Antibody

Catalog Number: (10075-602)
Supplier: Prosci
Description: The metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cyclase.
Image Unavailable-102944-320

Mouse Recombinant CNDP2/CNDP dipeptidase 2/Cytosolic non-specific dipeptidase/Glutamate carboxypeptidase-like protein 1/Cn2

Supplier: Bon Opus Biosciences
Description: Bon Opus Biosciences offers quality recombinant proteins products covering a broad collection of cytokines, enzymes, diagnostic and detection reagents, and other protein-related products

Product Image-89318-584

Anti-SSB Rabbit Polyclonal Antibody

Catalog Number: (89318-584)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to GAD67 (glutamate decarboxylase 1 (brain, 67kDa))
Image Unavailable-10366-992

Anti-GRIN1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10366-992)
Supplier: Bioss
Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
Image Unavailable-CAAAA10579-18

3-Nitrobenzoyl chloride 98%

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00007247 Beilstein Registry No.: 777186

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Image Unavailable-89349-860

Anti-MGLUR5 Rabbit Polyclonal Antibody

Catalog Number: (89349-860)
Supplier: Genetex
Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors (GPCRs) that contain 7 membrane-spanning domains and a large extracellular N-terminal region. The group I receptors mGluR1 and mGluR5 activate phospholipase C. By screening a human brain cDNA library with a rat mGluR1-alpha cDNA under low stringency conditions, Minakami et al. (1993) and Minakami et al. (1994) isolated human cDNAs encoding mGluR5. Minakami et al. (1993) identified a longer isoform of mGluR5 (mGluR5B).
Image Unavailable-89359-558

Anti-GPRC1C Rabbit Polyclonal Antibody

Catalog Number: (89359-558)
Supplier: Genetex
Description: L glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups. Group II receptors include GRM3 and are linked to the inhibition of the cyclic AMP cascade.
Product Image-89358-478

Anti-ATE1 Rabbit Polyclonal Antibody

Catalog Number: (89358-478)
Supplier: Genetex
Description: This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq]
Image Unavailable-89361-954

Anti-GS Goat Polyclonal Antibody

Catalog Number: (89361-954)
Supplier: Genetex
Description: Glutamine Synthetase (GS) catalyzes the conversion of ammonia and glutamate to glutamine. This reaction consumes a molecule of ATP:Glutamate + NH4+ + ATP --> Glutamine + ADP + Pi. GS is found in astrocytes as an octamer of identical 45kDa subunits. The function of GS is the detoxification of brain ammonia. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer s disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. On the other hands, the level of expression of GS is increased during ischemia in vivo or hypoxia in culture.
Image Unavailable-76101-188

Anti-Metabotropic Glutamate Receptor 4+6 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76101-188)
Supplier: Bioss
Description: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Product Image-10101-154

Anti-GRIK2 Rabbit Polyclonal Antibody

Catalog Number: (10101-154)
Supplier: Prosci
Description: This gene, GRIK2, encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory neurotransmission in the brain. This receptor may have a role in synaptic plasticity and may be important for learning and memory. It also may be involved in the transmission of light information from the retina to the hypothalamus. The structure and function of the encoded protein is changed by RNA editing.
Image Unavailable-10366-990

Anti-GRIN1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10366-990)
Supplier: Bioss
Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
Image Unavailable-10372-202

Anti-GRIN1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10372-202)
Supplier: Bioss
Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
Image Unavailable-10372-204

Anti-GRIN1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10372-204)
Supplier: Bioss
Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
Image Unavailable-TCN0846-1G

Neu5Ac[1Me,4789Ac]α(2-3)Gal[246Bz]-β-MP ≥95.0% (by HPLC)

Supplier: TCI America
Description: Molecular Weight: 1072.04
Purity/Analysis Method: >95.0% (HPLC)
Form: Crystal
Storage Temperature: 0-10°C
Molecular Formula: C54H57NO22

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