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Product Image-10075-602

Anti-GRM5 Rabbit Polyclonal Antibody

Catalog Number: (10075-602)
Supplier: Prosci
Description: The metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cyclase.
Image Unavailable-CAAAAL09152-06

3-Fluorobenzoyl chloride 98%

Supplier: Thermo Scientific Chemicals
Description: 3-Fluorobenzoyl chloride 98%

Certificates

Product Image-89319-002

Anti-MRI1 Rabbit Polyclonal Antibody

Catalog Number: (89319-002)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to NMDAR2A (glutamate receptor, ionotropic, N-methyl D-aspartate 2A)
Image Unavailable-89356-872

Anti-GCLM Rabbit Polyclonal Antibody

Catalog Number: (89356-872)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to GCLM (glutamate-cysteine ligase, modifier subunit)
Image Unavailable-TCN0846-1G

Neu5Ac[1Me,4789Ac]α(2-3)Gal[246Bz]-β-MP ≥95.0% (by HPLC)

Supplier: TCI America
Description: Molecular Weight: 1072.04
Purity/Analysis Method: >95.0% (HPLC)
Form: Crystal
Storage Temperature: 0-10°C
Molecular Formula: C54H57NO22

SDS

Product Image-10100-592

Anti-GRM6 Rabbit Polyclonal Antibody

Catalog Number: (10100-592)
Supplier: Prosci
Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Product Image-77172-284

Anti-Glutamate Receptor 1 (AMPA subtype) Mouse Monoclonal Antibody [Clone: S355-1]

Catalog Number: (77172-284)
Supplier: ANTIBODIES.COM LLC
Description: Mouse monoclonal [S355-1] antibody to Glutamate Receptor 1 (AMPA subtype) for WB, IHC and ICC/IF with samples derived from Human, Mouse and Rat.
Product Image-89320-576

Anti-NBPF4 Rabbit Polyclonal Antibody

Catalog Number: (89320-576)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to SLC25A22 (solute carrier family 25 (mitochondrial carrier: glutamate), member 22)
Image Unavailable-10366-994

Anti-GRIN1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10366-994)
Supplier: Bioss
Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
Image Unavailable-77438-242

Anti-SHISA6 Rabbit Polyclonal Antibody

Catalog Number: (77438-242)
Supplier: Bioss
Description: Involved in maintenance of high-frequency synaptic transmission at hippocampal CA3-CA1 synapses. Regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression. May play a role in self-renewal and differentiation of spermatogonial stem cells by inhibiting canonical Wnt signaling pathway.
Image Unavailable-CAAAA10579-18

3-Nitrobenzoyl chloride 98%

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00007247 Beilstein Registry No.: 777186

Certificates

Image Unavailable-77440-244

Anti-MGLUR1A/Metabotropic Glutamate Receptor 1a Rabbit Polyclonal Antibody

Catalog Number: (77440-244)
Supplier: Bioss
Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternative splice variants of the GRM1 gene have been described but their full-length nature has not been determined.
Image Unavailable-ABCA_AB196929-100U

Anti-Metabotropic Glutamate Receptor 5 Rabbit Monoclonal Antibody [clone: EPR2425Y] (Alexa Fluor® 647)

Catalog Number: (ABCA_AB196929-100U)
Supplier: Abcam
Description: Alexa Fluor® 647 Rabbit monoclonal [EPR2425Y] to Metabotropic Glutamate Receptor 5.

New Product


Image Unavailable-76101-188

Anti-Metabotropic Glutamate Receptor 4+6 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76101-188)
Supplier: Bioss
Description: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Image Unavailable-ABCA_AB316807-100U

Anti-Metabotropic Glutamate Receptor 3/MGLUR3 Rabbit Monoclonal Antibody [clone: EPR24635-17]

Supplier: Abcam
Description: Rabbit monoclonal [EPR24635-17] to Metabotropic Glutamate Receptor 3/MGLUR3 - BSA and Azide free (Capture).

New Product

Image Unavailable-76100-934

Anti-GLUR4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76100-934)
Supplier: Bioss
Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties.
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