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Mouse Recombinant Sonic Hedgehog (from E. coli)

Catalog Number: (75791-156)
Supplier: Prosci
Description: Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases.Mouse Shh is synthesized as a 437 aa precursor that contains a 24 aa signal sequence and a 413 aa mature region. The mature region is autocatalytically processed into a nonglycosylated, 20 kDa, 174 aa N­terminal fragment (Shh­N), and a catalytic­processing,glycosylated, 34 kDa, 239 aa C­terminal fragment. The 20 kDa Shh­N fragment is the core of the active hedgehog molecule. Mouse Shh­N is 99%, 98%, and 100% aa identical to human, rat and gerbil Shh­N, respectively.
Product Image-CA89174-470

Nunc® Centrifuge Tubes, Polypropylene, Conical, Sterile, Thermo Scientific

Supplier: Thermo Fisher Scientific
Description: The Nunc® conical sterile polypropylene centrifuge tubes are premium, high quality, and environmentally friendly conical tubes.

Certificates

Product Image-71001-612

PYREX® HPLC Reservoir, Single Cavity, Corning

Supplier: Corning
Description: These PYREX® HPLC reservoirs have a central cavity for a mobile phase inlet reservoir, an autoclavable plastic coat that absorbs UV up to 385 nm, and a GL45 thread finish.

Environmentally Preferable Product available on GSA Advantage®

Image Unavailable-77269-628

Mobile Stand-Alone Pegboard Unit with Four Black ABS Textured Finish DuraBoard® Pegboards

Catalog Number: (77269-628)
Supplier: Triton Products
Description: Mobile pegboard units offer maximum tool board storage versatility and strength with 32 sq. ft. of pegboard storage space.
Image Unavailable-77269-634

Mobile Stand-Alone Pegboard Unit with Four White High Density Fiberboard Pegboards

Catalog Number: (77269-634)
Supplier: Triton Products
Description: Mobile Pegboard Units offer maximum tool board storage versatility and strength with 32 sq. ft. of pegboard storage space.
Product Image-77682-534

Hepatitis C virus (HCV) Recombinant NS4

Catalog Number: (77682-534)
Supplier: Creative Biomart
Description: Recombinant HCV Genotype-5 NS4 Mosaic Antigen, GST-tagged.

New Product


Product Image-470026-808

What is a Fossil? Activity Set

Catalog Number: (470026-808)
Supplier: Avantor
Description: Ideal learning tool for introductory geology classes.
Product Image-CAJT0092-5

Orthoboric acid 99.5-100.5% (dry basis), granular NF, Multi-Compendial, J.T.Baker®

Catalog Number: (CAJT0092-5)
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Granular.

Certificates


Product Image-76670-460

VWR® Stackable Mini Rollers

Catalog Number: (76670-460)
Supplier: VWR International
Description: VWR® Stackable mini rollers, designed for gentle agitation of multiple sized bottles/tubes in a space saving footprint.

2 year warranty


Product Image-470013-006

Spectrum Tubes

Supplier: American Scientific
Description: Spectrum Tubes demonstrate the wave properties of different gases.

Product Image-470044-362

Science Take-Out® Birth Defects And Folic Acid

Supplier: SCIENCE TAKE-OUT, LLC
Description: How Does Folic Acid Prevent Neural Tube Defects?

Image Unavailable-75794-504

Mouse Recombinant IL-4 non-lytic (from CHO Cells)

Catalog Number: (75794-504)
Supplier: Prosci
Description: Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.
Image Unavailable-75794-512

Human Recombinant IL-6 non-lytic (from CHO Cells)

Catalog Number: (75794-512)
Supplier: Prosci
Description: Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
Product Image-76577-978

Plant Zucchini Yellow Mosaic Virus (ZYMV) ELISA Kit, AFG Bioscience

Catalog Number: (76577-978)
Supplier: AFG Bioscience
Description: Plant Zucchini Yellow Mosaic Virus (ZYMV) ELISA Kit, AFG Bioscience
Product Image-89090-586

PYREXPLUS® Graduated Cylinders, To Deliver, Corning

Catalog Number: (89090-586)
Supplier: Corning
Description: Borosilicate glass.

Certificates Environmentally Preferable Product available on GSA Advantage®


Product Image-100500-478

Nunc® Nunclon™ Multi-Dishes, Electron Microscopy Sciences

Supplier: Electron Microscopy Sciences
Description: The NUNC™ Coverglass Optical Bottom 96 Well Plates have an optically clear polystyrene plate bottom. This clear base permits microscopic viewing and reading of well The plate’s upper structure is offered in black for fluorometric detection. External dimension: 128 x 86 mm.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
You must log in to order restricted items. We request that you provide the required business documentation to purchase this product for the first time.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
  • Government issued document with your organization's Resale Tax ID Number
  • Any other Government ID that includes the business name and address


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