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Description: IL-1RAcP Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I(IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kappa B inducing kinae (NIK) and of NF-kappa B, recruites to the IL-1R complex through IL-1 RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.
Catalog Number: 89415-334
Supplier: Prosci


Description: IL-1RAcP Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kappa B inducing kinae (NIK) and of NF-kappa B, recruits to the IL-1R complex through IL-1RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.
Catalog Number: 89415-332
Supplier: Prosci


Description: CAS Number: 944450-45-7
MDL Number: MFCD09753031
Molecular Formula: C60H60Cl2N2O4P2Ru
Molecular Weight: 1107.07
Form: Crystal
Color: Yellow
Catalog Number: TCR0131-200MG
Supplier: TCI America

SDS


Description: Antifungal and immunosuppressant
Catalog Number: CA80054-246
Supplier: MilliporeSigma

Description: IL-33 Antibody: Interleukin-33 (IL-33) is a recently identified member of the IL-1 family of cytokines whose other members include IL-1 alpha /beta, IL-1Ra and IL-18. Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and IL-1R accessory protein (IL-1RAcP). Receptor binding of IL-33 activates NF-kappa B and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine. Recent experiments have shown that IL-33 can also co-localize with heterochromatin and possesses transcriptional repressor activities, indicating that IL-33 may function as both a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties.
Catalog Number: 89416-316
Supplier: Prosci


Description: IL-33 Antibody: Interleukin-33 (IL-33) is a recently identified member of the IL-1 family of cytokines whose other members include IL-1 alpha /beta, IL-1Ra and IL-18. Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and IL-1R accessory protein (IL-1RAcP). Receptor binding of IL-33 activates NF-kappa B and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine. Recent experiments have shown that IL-33 can also co-localize with heterochromatin and possesses transcriptional repressor activities, indicating that IL-33 may function as both a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties.
Catalog Number: 89416-314
Supplier: Prosci


Description: Human IGF1R AccuSignal ELISA Kit
Catalog Number: 76235-632
Supplier: Rockland Immunochemical


Description: CAS Number: 579-43-1
MDL Number: MFCD00064253
Molecular Formula: C14H14O2
Molecular Weight: 214.26
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 136
Catalog Number: TCH0816-25G
Supplier: TCI America

Description: (R)-(+)-α-Methylbenzylamine ≥99%, ee 99%, ChiPros®
Catalog Number: CAAAAL19117-06
Supplier: Thermo Scientific Chemicals

Description: CAS Number: 472-15-1
Molecular Formula: C30H48O3
Molecular Weight: 456.71
Purity/Analysis Method: >97.0% (GC,T)
Form: Crystal
Melting point (°C): 294
Specific rotation [a]20/D: 7.8 deg (C=0.9, Pyridine)
Catalog Number: TCB2836-1G
Supplier: TCI America

Description: CAS Number: 55739-58-7
MDL Number: MFCD05863546
Molecular Formula: C28H28O2P2
Molecular Weight: 458.48
Purity/Analysis Method: >97.0% (GC,T)
Form: Crystal
Melting point (°C): 104
Specific rotation [a]20/D: -85 deg (C=1, CHCl3)
Catalog Number: TCB3035-100MG
Supplier: TCI America

SDS


Description: An antifungal, anti-yeast and anti-mold reagent.
Catalog Number: CA82026-728
Supplier: Cytiva


Description: A polyene antifungal antibiotic that nonspecifically induces loss of low molecular weight substances from cells
Catalog Number: CA80055-790
Supplier: MilliporeSigma

Description: This peptide is Srctide with an N-terminal 5-FAM (Ex/Em=494/521 nm) label. Srctide is a substrate for many protein kinases, such as Blk, BTK, cKit, EPHA1, EPHB2, EPHB3, ERBB4, FAK, Flt3, IGF-1R, ITK, Lck, MET, MUSK, Ret, Src, TIE2, TrkB, VEGF-R1 (Flt-1) and VEGF-R2 (KDR).
Sequence:5-FAM-GEEPLYWSFPAKKK-NH2
MW:2037.3 Da
% peak area by HPLC:95
Storage condition:-20° C
Catalog Number: 103007-840
Supplier: Anaspec Inc


Description: CAS Number: 192139-92-7
MDL Number: MFCD10567385
Molecular Formula: C31H35ClN2O2RuS
Molecular Weight: 636.21
Purity/Analysis Method: >90% (HPLC)
Form: Crystal
Color: Yellow
Melting point (°C): 215
Specific rotation [a]20/D: -116 deg (C=0.1, CHCl3)
Catalog Number: TCR0125-200MG
Supplier: TCI America

SDS


Description: CAS Number: 220114-38-5
MDL Number: MFCD09753028
Molecular Formula: C66H64Cl2N2P2Ru
Molecular Weight: 1119.17
Form: Crystal
Color: Yellow
Catalog Number: TCR0135-200MG
Supplier: TCI America