You Searched For: 3,4-Dibromothiophene


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Description: 1-Ethyl-3-methylimidazolium bromide 98+%
Catalog Number: CAAAAL19761-18
Supplier: Thermo Scientific Chemicals

Description: 0.500 (+/-0.0002) Normal (N/2). ASTM D 1159 for Bromine Number of Petroleum Distillates. (0.2500 Molar as Br2). Glass Container. 4L.
Catalog Number: RC117232
Supplier: Ricca Chemical

Description: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
Catalog Number: 10460-476
Supplier: Bioss


Description: TdT inhibitor
Catalog Number: 89149-326
Supplier: Enzo Life Sciences


Description: Catalyst
Catalog Number: CAAA11605-A1
Supplier: Thermo Scientific Chemicals

Description: Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins.
Catalog Number: 10337-792
Supplier: Bioss


Description: Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins.
Catalog Number: 10337-786
Supplier: Bioss


Description: Phenylmagnesium bromide, 3M in ether, Cas Number: 100-58-3, Molecular Formula: C6H5MgBr, Color: yellow to brown, Form: Liquid, Size: 500ML
Catalog Number: AA87326-AE
Supplier: Thermo Scientific Chemicals

Description: (3-Phenylpropyl)triphenylphosphonium bromide 98%
Catalog Number: CAAAA12669-09
Supplier: Thermo Scientific Chemicals

Description: MDL: MFCD00064630
Catalog Number: CAAA39388-14
Supplier: Thermo Scientific Chemicals

Description: MDL: MFCD00011767 Beilstein Registry No.: 3597463
Catalog Number: CAAAA10761-18
Supplier: Thermo Scientific Chemicals

Description: A fluorescent photoaffinity label that couples covalently to nucleic acids upon light irradiation
Catalog Number: 103011-138
Supplier: Anaspec Inc


Description: (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide 98%
Catalog Number: CAAAA18882-30
Supplier: Thermo Scientific Chemicals

Description: Triethylbutylammonium bromide 97%
Catalog Number: CAAAB24128-22
Supplier: Thermo Scientific Chemicals

Description: CAS Number: 2091-46-5
MDL Number: MFCD00011811
Molecular Formula: C21H18BrP
Molecular Weight: 381.25
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Color: White
Catalog Number: TCP1438-5G
Supplier: TCI America

SDS


Description: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
Catalog Number: 76119-134
Supplier: Bioss


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