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Image Unavailable-10414-486

Anti-GRIN2B Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10414-486)
Supplier: Bioss
Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
Image Unavailable-10448-472

Anti-KCNJ8 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10448-472)
Supplier: Bioss
Description: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).
Image Unavailable-10452-326

Anti-KCNJ3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10452-326)
Supplier: Bioss
Description: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Image Unavailable-76099-858

Anti-HEAB Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Catalog Number: (76099-858)
Supplier: Bioss
Description: HEAB is a 425 amino acid nuclear protein that belongs to the Clp1 family. Utilizing magnesium, manganese or nickel as cofactors, HEAB participates in the phosphorylation of the 5'-hydroxyl groups of double- and single- stranded RNA and DNA. HEAB is a member of the tRNA splicing endonuclease complex, in conjunction with TSEN2, TSEN15, TSEN34 and TSEN54, and is also a member of the pre-mRNA cleavage complex II. The gene encoding HEAB maps to human chromosome 11q12.1 and mouse chromosome 2 D; mutations to this gene may lead to a reduced pre-mRNA cleavage activity. HEAB exists as two isoforms due to alternative splicing events.
Product Image-10751-312

Anti-SIK1 Rabbit Polyclonal Antibody

Catalog Number: (10751-312)
Supplier: Prosci
Description: SIK1 Antibody: Salt-inducible kinase 1 (SIK1), also known as SNF1LK or MSK, plays a role in histone modification and G2/M cell cycle regulation. It is a 783 amino acid protein that contains one UBA domain and belongs to the Ser/Thr protein kinase family (AMPK subfamily). Localized to both the nucleus and the cytoplasm, SIK1 is a class II HDAC kinase that uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation.
Image Unavailable-10414-350

Anti-G3BP1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10414-350)
Supplier: Bioss
Description: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
Image Unavailable-CAPIPA5-18180

Anti-PPP1R8 Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18180)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
Image Unavailable-76080-334

Anti-G3BP1Ser232 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76080-334)
Supplier: Bioss
Description: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
Image Unavailable-10164-742

Anti-MRS2 Rabbit Polyclonal Antibody

Catalog Number: (10164-742)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to Hpt
Product Image-10749-022

Anti-PPM1D Rabbit Polyclonal Antibody

Catalog Number: (10749-022)
Supplier: Prosci
Description: Wild-type p53 induced phosphatase 1 (WIP1) / protein phosphatase magnesium-dependent 1 delta (PPM1D), a protein identified in the p53 DNA response pathway, is a member of the PP2C family of serine/threonine protein phosphatases which selectively inactivates p38 MAPK and dephosphorylates the ATM/ATR targets, Chk1 and p53. Studies have shown that it is overexpressed in human cancers and is involved in the regulation of multiple DNA damage signaling pathways. PPM1D deletion results in a reduction of T and B cell function and compromised cell division, rendering cells resistant to becoming cancerous and slowing tumor development.
Image Unavailable-76082-230

Anti-NMDAR2B Tyr1070 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76082-230)
Supplier: Bioss
Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
Image Unavailable-76116-366

Anti-kir 6.1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76116-366)
Supplier: Bioss
Description: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).
Image Unavailable-89268-478

Anti-MRS2L Rabbit Polyclonal Antibody

Catalog Number: (89268-478)
Supplier: Genetex
Description: Rabbit polyclonal antibody to MRS2L (Middle)
Product Image-CA200064-480

BtsCI

Catalog Number: (CA200064-480)
Supplier: New England Biolabs (NEB)
Description: An E.coli strain that carries the BtsCI gene from Bacillus thermosphaericus (X. Pan).
Image Unavailable-76118-594

Anti-GIRK3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76118-594)
Supplier: Bioss
Description: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Product Image-CA11016-884

EGTA solution

Catalog Number: (CA11016-884)
Supplier: Hach
Description: For calcium and magnesium hardness determination by the Calmagite colorimetric method

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