You Searched For: Benzimidazole-5,6-dicarboxylic+acid

Supplier: AGILENT TECHNOLOGIES (GENOMICS) CA

Description: This DNA polymerase is ideal for a variety of techniques requiring high-fidelity DNA synthesis by the polymerase chain reaction (PCR).

Catalog Number: (CAPIPA5-18787)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with mouse and rat based on sequence homology. BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

Catalog Number: (470335-416)

Supplier: LaMotte

Description: Precalibrated test tubes and labware give fast, accurate results on-site, in the classroom, or in the lab.

Catalog Number: (CA101227-464)

Supplier: New England Biolabs (NEB)

Description: New England Biolabs provides a color-coded 10X NEBuffer with each restriction endonuclease to ensure optimal (100%) activity

Catalog Number: (75977-392)

Supplier: Biotium

Description: DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Catalog Number: (CA99900-532)

Supplier: AGILENT TECHNOLOGIES (GENOMICS) CA

Description: Highly purified, recombinant Taq DNA Polymerase cloned from thermophilic eubacteria, <i>Thermus aquaticus</i>.

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Supplier: AGILENT TECHNOLOGIES (GENOMICS) CA

Description: This DNA polymerase is ideal for a variety of techniques requiring high-fidelity DNA synthesis by the polymerase chain reaction (PCR).

Catalog Number: (10479-760)

Supplier: Bioss

Description: The FAH family contains two highly homologous 314 amino acid proteins, designated FAHD2A (fumarylacetoacetate hydrolase domain-containing protein 2A) and FAHD2B (fumarylacetoacetate hydrolase domain-containing protein 2A). FAHD2A and B utilize calcium and magnesium as cofactors, and may possess hydrolase activity. The genes encoding FAHD2A/B map to human chromosome 2, the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome, is also associated with mutations to chromosome 2.

Catalog Number: (CA101227-374)

Supplier: New England Biolabs (NEB)

Description: New England Biolabs supplies a 10X reaction buffer with all of its enzymes

Catalog Number: (10751-300)

Supplier: Prosci

Description: ATP2C1 Antibody: ATP2C1, also known as secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1, belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder characterized by persistent blisters and erosions of the skin. Unlike the related protein ATP2C2, ATP2C1 is ubiquitously expressed and displays a lower maximal turnover rate for overall Ca2+-ATPase reaction and a higher apparent affinity for cytosolic Ca2+ activation of phosphorylation. Recent evidence suggests that ATP2C1 is a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers.

Catalog Number: (CA610-705-002)

Supplier: Rockland Immunochemical

Description: Secondary Donkey Anti-IgG (H&L) Reacts with Mouse

Catalog Number: (CA200067-224)

Supplier: New England Biolabs (NEB)

Description: An E.coli strain that expresses only the large subunit of the BtsI restriction gene from Bacillus thermoglucosidasius (X.Pan).

Supplier: New England Biolabs (NEB)

Description: An E.coli strain that carries the cloned and modified BtsI gene from Bacillus thermoglucosidasius (X. Pan).

Supplier: New England Biolabs (NEB)

Description: An E.coli strain that carries the cloned PspOMI gene from Pseudomonas species OM2164, (S.K. Degtyarev).

Catalog Number: (10479-754)

Supplier: Bioss

Description: The FAH family contains two highly homologous 314 amino acid proteins, designated FAHD2A (fumarylacetoacetate hydrolase domain-containing protein 2A) and FAHD2B (fumarylacetoacetate hydrolase domain-containing protein 2A). FAHD2A and B utilize calcium and magnesium as cofactors, and may possess hydrolase activity. The genes encoding FAHD2A/B map to human chromosome 2, the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome, is also associated with mutations to chromosome 2.

Catalog Number: (CA76284-680)

Supplier: New England Biolabs (NEB)

Description: Thermostable RNase H is an endoribonuclease that is functional at high temperatures and selectively hydrolyzes the phosphodiester bonds of an RNA strand in an RNA:DNA hybrid molecule, while leaving the DNA strand intact.