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Catalog Number: (10094-234)
Supplier: Proteintech
Description: SDHB(Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial) is also named as SDH, SDH1 and belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. The SDHD, SDHB, and SDHC genes encode subunits of mitochondrial complex II (succinate dehydrogenase).Mitochondrial complex II is a heterotetrameric complex involved in the aerobic electron transport chain and catalyses the oxidation of succinate to fumarate (Krebs cycle) with transport of electrons to the ubiquinone pool. SDHA and SDHB are the hydrophilic catalytic part of the complex and are highly conserved(J Med Genet 2004;41:e99). Defects in SDHB are a cause of susceptibility to pheochromocytoma (PCC), paragangliomas type 4 (PGL4), paraganglioma and gastric stromal sarcoma (PGGSS) and Cowden-like syndrome (CWDLS).


Supplier: TCI America
Description: CAS Number: 19381-50-1
MDL Number: MFCD00003886
Molecular Formula: C30H18FeN3O15S3
Molecular Weight: 878.45
Purity/Analysis Method: >80.0% (E)
Form: Crystal
Lambda max.: 714 nm (0.02mol/L AcONH4 sol.)

SDS

Catalog Number: (76277-270)
Supplier: AMERICAN HAKKO PRODUCTS INC TE
Description: Accessories for FM-203 Dual Port Soldering System, American Hakko Products


Catalog Number: (89417-072)
Supplier: Prosci
Description: HAAO Antibody: HAAO (3-Hydroxyanthranilate 3, 4-dioxygenase) is a monomeric cytosolic protein of the family of intramolecular dioxygenases containing non-heme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is present in low amounts in the central nervous system. This enzyme participates in tryptophan metabolism. It employs one cofactor, iron. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurological and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. Furthermore, recent study shows that HAAO are excellent candidate biomarkers for detecting ovarian cancer.


Catalog Number: (10470-406)
Supplier: Bioss
Description: Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May bind and transfer a labile 4Fe-4S cluster to target apoproteins.


Catalog Number: (10451-812)
Supplier: Bioss
Description: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).


Catalog Number: (10470-410)
Supplier: Bioss
Description: Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May bind and transfer a labile 4Fe-4S cluster to target apoproteins.


Catalog Number: (10451-820)
Supplier: Bioss
Description: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).


Supplier: AmTab Manufacturing Corporation
Description: AmTab's cafe tables are used every day throughout the world in multi-purpose environments. High-quality state-of-the-art tables are safe, durable, easy to operate, perfect for heavy-use and heavy-turn settings providing years of trusted service.

Environmentally Preferable

Catalog Number: (89160-054)
Supplier: Enzo Life Sciences
Description: The rate limiting enzyme in heme catabolism, heme oxygenase, was first described in 1968 and was thought to be a species of cytochrome P450. However, subsequent work showed the enzyme to be a protein distinct from the P450 family and capable of catalysing the degradation of heme to biliverdin and iron, with the concomitant release of carbon monoxide. This enzyme activity is highly conserved throughout the Animal Kingdom and has been identified in algae and plants as well as in all higher species. Heme oxygenase-1 (HO-1) was first purified to homogeneity from rat liver and pig spleen and shown to have a molecular weight of 32kDa. Increased expression of HO-1 can be induced by a large number of structurally unrelated pharmacological and other agents, including cytokines and oxidants, as well as by heat shock and other forms of cellular stress. Baseline levels of HO-1 expression are high in certain tissues, including spleen and liver, but enriched enzyme preparations are recommended for experimental analysis. Recent data have demonstrated a cytoprotective role for HO-1, preventing cell death by modulating intracellular iron levels.


Catalog Number: (76117-020)
Supplier: Bioss
Description: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.


Catalog Number: (CAPI23280)
Supplier: Thermo Scientific
Description: Pierce™ Quantitative Peroxide Assay Kit (Aqueous) detects and measures hydrogen peroxide levels in biological samples using an Iron and Xylenol orange* (XO) reagent.

Catalog Number: (10470-408)
Supplier: Bioss
Description: Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May bind and transfer a labile 4Fe-4S cluster to target apoproteins.


Supplier: Restek
Description: Multiple models of photoionization detector lamps are available in a variety of sizes and lamp outputs.

Catalog Number: (10108-868)
Supplier: Prosci
Description: Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes.


Catalog Number: (CA11019-704)
Supplier: A.R. Olympique
Description: Accessories for MAS Furnaces, Anachemia


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