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Description: The AFS98 antibody is specific for mouse CD115, also known as Colony-Stimulating Factor-1 Receptor (CSF-1R), a 145 kDa receptor from the PDGF receptor family. Receptor activation by the ligands IL-34 or CSF-1 (M-CSF) occurs via homodimerization of CD115 and subsequent tyrosine phosphorylation and ubiquitination of intracellular domains. CD115 signaling promotes differentiation of myeloid precursors, as well as the continued regulation of proliferation, survival and function of mononuclear phagocytes, dendritic cells and osteoclasts. While IL-34 and CSF-1 may induce similar cellular responses, they are differentially expressed and as such exert complimentary actions via CD115.
Catalog Number: 10050-960
Supplier: Tonbo Biosciences


Description: The AFS98 antibody is specific for mouse CD115, also known as Colony-Stimulating Factor-1 Receptor (CSF-1R), a 145 kDa receptor from the PDGF receptor family. Receptor activation by the ligands IL-34 or CSF-1 (M-CSF) occurs via homodimerization of CD115 and subsequent tyrosine phosphorylation and ubiquitination of intracellular domains. CD115 signaling promotes differentiation of myeloid precursors, as well as the continued regulation of proliferation, survival and function of mononuclear phagocytes, dendritic cells and osteoclasts. While IL-34 and CSF-1 may induce similar cellular responses, they are differentially expressed and as such exert complimentary actions via CD115.
Catalog Number: 10141-202
Supplier: Tonbo Biosciences


Description: This digital laboratory stirrer achieves high torque enabling stirring of high viscosity solution.
Catalog Number: 75846-392
Supplier: Yamato Scientific


Description: Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65000. The human albumin gene is 16961 nucleotides long from the putative & apos;c ap & apos; site to the first poly(A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.
Catalog Number: 76121-198
Supplier: Bioss


Description: Produced from a custom grade low-density polyethylene (LDPE), these unbreakable one-piece pipettes are used to draw and dispense liquids in controlled, reproducible drop sizes.
Catalog Number: 76285-412
Supplier: Globe Scientific


Description: Calcein, AM is a cell-permeant and non-fluorescent compound that is widely used for determining cell viability
Catalog Number: 103011-230
Supplier: Anaspec Inc


Description: The AFS98 antibody is specific for mouse CD115, also known as Colony-Stimulating Factor-1 Receptor (CSF-1R), a 145 kDa receptor from the PDGF receptor family. Receptor activation by the ligands IL-34 or CSF-1 (M-CSF) occurs via homodimerization of CD115 and subsequent tyrosine phosphorylation and ubiquitination of intracellular domains. CD115 signaling promotes differentiation of myeloid precursors, as well as the continued regulation of proliferation, survival and function of mononuclear phagocytes, dendritic cells and osteoclasts. While IL-34 and CSF-1 may induce similar cellular responses, they are differentially expressed and as such exert complimentary actions via CD115.
Catalog Number: 10050-562
Supplier: Tonbo Biosciences


Description: CAS Number: 65-46-3
MDL Number: MFCD00006545
Molecular Formula: C9H13N3O5
Molecular Weight: 243.22
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Specific rotation [a]20/D: 34 deg (C=0.7, H2O)
Catalog Number: TCC0522-5G
Supplier: TCI America

Description: CAS Number: 5399-02-0
MDL Number: MFCD00042635
Molecular Formula: C17H33N
Molecular Weight: 251.46
Purity/Analysis Method: >95.0% (GC)
Form: Crystal
Boiling point (°C): 208
Melting point (°C): 34
Catalog Number: TCH0568-025G
Supplier: TCI America

SDS


Description: CDK6(Cyclin-dependent kinase 6) is involved in initiation and maintenance of cell cycle exit during cell differentiation and it prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types.The range of the molecular weight is 34-50 KDa.
Catalog Number: 10084-530
Supplier: Proteintech


Description: CAS Number: 1195-09-1
MDL Number: MFCD00040901
Molecular Formula: C8H10O2
Molecular Weight: 138.17
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Boiling point (°C): 117
Freezing point (°C): 34
Catalog Number: TCH0624-25G
Supplier: TCI America

Description: CAS Number: 637-89-8
MDL Number: MFCD00004850
Molecular Formula: C6H6OS
Molecular Weight: 126.17
Purity/Analysis Method: >97.0% (GC,T)
Form: Crystal
Flash Point (°C): 110
Freezing point (°C): 34
Catalog Number: TCH0662-025G
Supplier: TCI America

Description: Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65000. The human albumin gene is 16961 nucleotides long from the putative 'cap' site to the first poly(A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.
Catalog Number: 76121-200
Supplier: Bioss


Description: The AFS98 antibody is specific for mouse CD115, also known as Colony-Stimulating Factor-1 Receptor (CSF-1R), a 145 kDa receptor from the PDGF receptor family. Receptor activation by the ligands IL-34 or CSF-1 (M-CSF) occurs via homodimerization of CD115 and subsequent tyrosine phosphorylation and ubiquitination of intracellular domains. CD115 signaling promotes differentiation of myeloid precursors, as well as the continued regulation of proliferation, survival and function of mononuclear phagocytes, dendritic cells and osteoclasts. While IL-34 and CSF-1 may induce similar cellular responses, they are differentially expressed and as such exert complimentary actions via CD115.
Catalog Number: 10051-102
Supplier: Tonbo Biosciences


Description: CAS Number: 2168-93-6
MDL Number: MFCD00002093
Molecular Formula: C8H18OS
Molecular Weight: 162.29
Purity/Analysis Method: >96.0% (GC)
Form: Crystal
Flash Point (°C): 121
Freezing point (°C): 34
Catalog Number: TCD1173-5G
Supplier: TCI America

Description: CAS Number: 52182-15-7
MDL Number: MFCD00016850
Molecular Formula: C16H16O3
Molecular Weight: 256.30
Purity/Analysis Method: >97.0% (GC)
Form: Crystal
Boiling point (°C): 190
Melting point (°C): 34
Catalog Number: TCE0747-5G
Supplier: TCI America

SDS


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