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Image Unavailable-10403-666

Anti-MMP2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10403-666)
Supplier: Bioss
Description: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
Image Unavailable-76078-914

Anti-MMP-2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76078-914)
Supplier: Bioss
Description: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
Product Image-MFLX05620-83

GF Signet PVC Saddle Installation Fittings

Supplier: BURT PROCESS EQUIPMENT
Description: Ensure proper insertion depth and measurement.

Product Image-CA89095-780

VWR® DURAC Plus Dry Block/Incubator Liquid-In-Glass Thermometer; Organic Liquid Fill

Catalog Number: (CA89095-780)
Supplier: VWR International
Description: Ideal for use in all standard heating blocks and water baths, these thermometers contain blue organic liquid fill against lead-free white back glass.

Certificates


Image Unavailable-10404-026

Anti-ROCK1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10404-026)
Supplier: Bioss
Description: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress. Acts as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Required for centrosome positioning and centrosome-dependent exit from mitosis. Plays a role in terminal erythroid differentiation. May regulate closure of the eyelids and ventral body wall by inducing the assembly of actomyosin bundles. Promotes keratinocyte terminal differentiation. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization.
Product Image-MFLX32654-08

Hydrogen (H2) Gas Mass Flowmeters with Metal bodies

Supplier: AALBORG INSTRUMENTS & CONTROL
Description: Precisely measure flow rates and totals.

NIST traceable

Product Image-34787-114

VWR® Brix Sugar Scale Plain Form Hydrometers, Traceable to NIST

Supplier: VWR International
Description: Used in the food and beverage and other industries for measuring % sucrose by weight, these plain form hydrometers are available in various ranges from 0° to 71° Brix.

Product Image-470106-454

Flat Plastic Meter Stick

Catalog Number: (470106-454)
Supplier: SI Manufacturing
Description: Flexible plastic meter stick marked in cm with 1 mm divisions on one side and with alternate-colored dm bars on the other, to show the relationships between units.
Product Image-34780-002

VWR® Salt Brine Plain Form Hydrometers, Traceable to NIST

Supplier: VWR International
Description: Used for measuring sodium chloride saturation of salt brines in various industries including food, fishing, and transportation.

Certificates

Product Image-89415-780

Anti-CASP2 Rabbit Polyclonal Antibody

Catalog Number: (89415-780)
Supplier: Prosci
Description: Caspase-2 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1 beta and IL-18. Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis. Caspase-2 has two major isoforms; overexpression on the long form results in apoptosis while that of the short form suppresses cell death.
Product Image-10170-872

Heat Exchangers for Bioreactors, Chemglass

Supplier: Chemglass
Description: Heat exchangers are available in a choice of two different styles.

Image Unavailable-102979-288

Anti-TG Monoclonal Antibody [clone: 2E8]

Catalog Number: (102979-288)
Supplier: Adipogen
Description: Thymidineglycol (TG) is one of the major oxidation products of DNA. Thymidine (T) can be damaged by oxidative stress such as radiation and energy metabolism. Two different pathways to form TG have been suggested. Deoxythymidine in DNA is directly oxidised by hydroxy radical, to form TG. TG can be also formed through an intermediate thymidine chlorohydrin, which is derived from hypochlorous acid (HOCl) from neutrophil myeloperoxidase. Thymidineglycol is derived from DNA, not from RNA. TG is the oxidative stress marker secific for DNA damage. In comparison with 8-hydroxy-2'-deoxyguanosine (8-OHdG), which is the best known DNA oxidation product it was shown that in a lipopolysaccharide (LPS)-treated mouse liver, 8-OHdG can be stained within 24 hours after LPS treatment. TG can be detected within 6 hours, and remains at least for 72 hours.
Image Unavailable-CAPIPA5-13953

Anti-MKNK2 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-13953)
Supplier: Thermo Scientific
Description: MKNK2 may play a role in the response to environmental stress and cytokines. This protein appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Product Image-76208-076

Accessories for Oakton® PCTS Testr™ 50 Waterproof Pocket pH/Cond/TDS/Salinity Tester, Premium 50 Series, Cole Palmer

Catalog Number: (76208-076)
Supplier: Cole-Parmer Instrument Co.
Description: Replacement pH/Conductivity/TDS/Salinity Sensor PCTS 50 for Waterproof Pocket PCTS Testr* 50 pH/Cond/TDS/Salinity Tester
Product Image-76307-710

Sound Recorder/Datalogger, Certified, Sper Scientific

Catalog Number: (76307-710)
Supplier: Sper Scientific
Description: This unique sound meter enables you to playback a live audio recording that is synced with the measured sound intensity graph. It can quickly collect and analyze all standard sound data such as dB levels, LEQ and SPL, but also allows you to pinpoint the cause of various sound levels using the live recording.
Product Image-89415-782

Anti-CASP4 Rabbit Polyclonal Antibody

Catalog Number: (89415-782)
Supplier: Prosci
Description: Caspase-4 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1 beta and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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