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Catalog Number: (10749-540)
Supplier: Prosci
Description: ATR Antibody: The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8). This protein, which exists in three isoforms (36, 40, and 60 kDa), is highly expressed in tumor vessels as well as in the vasculature of developing embryos, suggesting that it may normally play a role in angiogenesis. However, it also acts as the receptor for anthrax toxin. Following the binding of this protein by the protective antigen (PA) of anthrax, PA is cleaved and heptamerizes to form the binding site for both edema factor (EF) and lethal factor (LF). This complex is then endocytosed by the cell; acidification in endosomes allows the release of EF and LF into the cytoplasm where they interfere with MAPK signaling and induce apoptosis.


Catalog Number: (CABD353928)
Supplier: Corning
Description: Nontreated, hydrophobic polystyrene surface. For use with BD Falcon HTS FluoroBlok* 96-Multiwell Insert Systems (BD351161, BD351162, BD351163, BD351164). Sterile, nonpyrogenic.

Catalog Number: (10110-704)
Supplier: Prosci
Description: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]). Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).


Catalog Number: (10108-294)
Supplier: Prosci
Description: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.


Supplier: Corning
Description: Plates are available in V-bottom and round-bottom formats to meet a wide variety of assay and storage needs.
Catalog Number: (77437-954)
Supplier: Bioss
Description: Involved in Golgi-to-ER retrograde transport. Functions as a host factor required for infection by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT toxins.


Catalog Number: (10783-984)
Supplier: CHI Scientific
Description: Kit PrimaCell*3 Rat Brain FIBROUT*3: Fibroblast Inhibitory System (for 500 ml medium), A mixture of cis-OH-proline, ricin toxin, gentamycin and formulated serum substitutes.


Supplier: CHI Scientific
Description: Kit PrimaCell*3 Rat Cervix FIBROUT*3: Fibroblast Inhibitory System (for 500 ml medium), A mixture of cis-OH-proline, ricin toxin, gentamycin and formulated serum substitutes.

Supplier: CHI Scientific
Description: PRimacell* Kit Human Artery Fibroblast Growth Inhibitors, Artery FibrOut* (5 x 200 ul) - A mixture of cis-OH-proline, ricin toxin, gentamycin and formulated serum substitutes

Supplier: CHI Scientific
Description: Kit PrimaCell* Mouse Prostate FIBROUT*: Fibroblast Inhibitory System (for 500 ml medium), A mixture of cis-OH-proline, ricin toxin, gentamycin and formulated serum substitutes

Catalog Number: (89415-576)
Supplier: Prosci
Description: ATR Antibody: The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8). This protein, which exists in three isoforms (36, 40, and 60 kDa), is highly expressed in tumor vessels as well as in the vasculature of developing embryos, suggesting that it may normally play a role in angiogenesis. However, it also acts as the receptor for anthrax toxin. Following the binding of this protein by the protective antigen (PA) of anthrax, PA is cleaved and heptamerizes to form the binding site for both edema factor (EF) and lethal factor (LF). This complex is then endocytosed by the cell; acidification in endosomes allows the release of EF and LF into the cytoplasm where they interfere with MAPK signaling and induce apoptosis.


Supplier: CHI Scientific
Description: Primacell* 3 Rat Intestine: Normal Intestinal Vein Endothelial Cells Growth Supplements with Serum (for 500 ml medium), A mixture of EGF, Insulin, Hydrocortisone, Cholera toxin, penicillin and streptomycin

Supplier: CHI Scientific
Description: Human Vertebal PrimaCell*, Normal Intervertebral Disc Nucleus Pulposus Growth Supplements with Serum (for 500 ml medium), A mixture of EGF, Insulin, Hydrocortisone, Cholera toxin, penicillin, and streptomycin.

Supplier: CHI Scientific
Description: Human Intestine Primacell*3: Normal Itestinal Vein Endothelial Cells Growth Supplements with Serum (for 500 ml medium), A mixture of EGF, Insulin, Hydrocortisone, Cholera toxin, penicillin, and streptomycin.

Supplier: CHI Scientific
Description: PrimaCell* 2 Rat Intestine, Normal Intestinal Smooth Muscle Cells Growth Supplements with Serum (for 500 ml medium), mixture of EGF, Insulin, Hydrocortisone, Cholera toxin, penicillin, and streptomycin

Supplier: CHI Scientific
Description: PrimaCell* 5 Human Lung, Normal Pulmonary Vein Endothelial Cells Growth Supplements with Serum (for 500 ml medium), mixture of EGF, Insulin, Hydrocortisone, Cholera toxin, penicillin, and streptomycin.

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