You Searched For: Gly-Arg-AMC

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[Lys(Me3)4]-Histone H3 (1-21)-GGK,Biotin

Catalog Number: (103007-964)

Supplier: Anaspec Inc

Description: This peptide is a synthetic peptide corresponding to amino acids 1-21 of human histone H3. It is trimethylated at lysine-4 with a C-terminal Gly-Gly linker followed by a biotinylated Lys. The trimethylation of histone H3 at lysine 4 [H3K4(Me3)] shows cell state and lineage potential by differentiating genes that are expressed, poised for expression, or repressed. H3K4(Me3) also labels imprinting control regions.
Sequence:ART-K(Me3)-QTARKSTGGKAPRKQLA-GGK(Biotin)-NH2
MW:2765.2 Da
% peak area by HPLC:95
Storage condition:-20° C

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(H-Cys-Gly-OH)₂

Supplier: Bachem Americas

Description: Please see also 5-(Pentafluorobenzoylamino)fluorescein (M-2375), a sensitive fluorogenic substrate for the determination of glutathione S-transferase (GST) activity and glutathione (GSH) concentration, and the carba-analog of GSH, ophthalmic acid, H-3145.

(Deamino-Cys¹,Val⁴,D-Arg⁸)-Vasopressin

Supplier: Bachem Americas

Description: For desmopressin see H-7675.

Z-Leu-Val-Gly-Diazomethyl Ketone

Supplier: Bachem Americas

Description: The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain.

Fmoc-Chg-OH 98%

Supplier: Thermo Scientific Chemicals

Description: N-Fmoc-2-cyclohexyl-L-glycine, 98%

SDS Certificates

Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH₂ Trifluoroacetate

Supplier: Bachem Americas

Description: The FRET substrate Mca-RPKPYA-Nva-WMK(Dnp)-amide was hydrolyzed 60 times more rapidly by stromelysin 1 (MMP-3) (kcat/Km= 59400 M⁻¹s⁻¹) than by interstitial collagenase (MMP-1). However, it showed little discrimination between MMP-3, gelatinase A (MMP-2) (kcat/Km= 54000 M⁻¹s⁻¹), and gelatinase B (MMP-9) (kcat/Km= 55300 M⁻¹s⁻¹). Metalloelastase (MMP-12) digested this fluorogenic substrate with a kcat/Km of 243000 M⁻¹s⁻¹. For a fluorescent standard see M-2250.

Pyr-Gly-OH

Supplier: Bachem Americas

Description: Epidermal dipeptide (EDP) inhibited the proliferation of retinal pigment epithelial (RPE) cells, a maximum inhibitory effect was reached at concentrations ranging from 10⁻¹³ to 10⁻¹⁵ M.

Glycine ≥99.0%, OmniPur®, Millipore®

Supplier: MilliporeSigma

Description: For molecular biology. DNase-, RNase-, protease-, and phosphatase-free.

SDS

Boc-Thr(Gly-Fmoc)-OH

Supplier: Bachem Americas

Description: Isoacyl dipeptides have been developed as building blocks for preventing aggregation of the growing peptide chains during Fmoc-SPPS. As the isopeptide structure is not affected by the final acidolytic cleavage the solubility of the crude product is improved facilitating the subsequent purification. The depsipeptide will rearrange yielding the desired product in slightly basic solution.

Rat;Mouse Ghrelin Peptide

Supplier: Anaspec Inc

Description: Rat/mouse Ghrelin differs from human Ghrelin on the 11th and 12th position - RV (Arg-Val) in rat/mouse and KA (Lys-Ala) in human. Ghrelin is an appetite stimulating peptide hormone secreted by stomach P/D1-type cells in humans and circulates in the bloodstream during fasting conditions. Enzymatically n-octanoylated Serine3 of this 28-amino acid Ghrelin is the endogenous ligand specific for growth hormone secretagogue receptor 1a (GHSR1a). The GHSR1a receptor appears to be dedicated to Ghrelin and is widely expressed in different tissues.
Sequence: GS-S(n-octanoyl)-FLSPEHQKAQQRKESKKPPAKLQPR
MW: 3314.8 Da
% Peak area by HPLC: 95
Storage condition: -20° C

Anti-PRMT5 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10459-276)

Supplier: Bioss

Description: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. May regulate the SUPT5H transcriptional elongation properties. May be part of a pathway that is connected to a chloride current, possibly through cytoskeletal rearrangement. Methylates histone H2A and H4 'Arg-3' during germ cell development. Methylates histone H3 'Arg-8', which may repress transcription. Methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. Methylates RPS10.