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Description: Sequence: Fmoc-Gly-OPfp
Catalog Number: B-1135.0001BA
Supplier: Bachem Americas


Description: Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP10. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein. Isoform 5, isoform 6, isoform 7 and isoform 8 lack the catalytic site and may interfere with the pro-apoptotic activity of the complex.
Catalog Number: 10447-528
Supplier: Bioss


Description: L(+)-Arginine 98.5-101.5% (dried basis) USP, FCC, Multi-Compendial, Macron Fine Chemicals™
Catalog Number: CAMK493207
Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Description: Sequence: Bz-Pro-Phe-Arg-pNA · HCl
Catalog Number: L-1545.0050BA
Supplier: Bachem Americas


Description: Sequence: Z-Gly-Pro-pNA
Catalog Number: L-1235.0250BA
Supplier: Bachem Americas


Description: Sequence: Fmoc-Gly-Wang resin (200-400 mesh)
Synonym(s): Fmoc-Gly-p-alkoxybenzyl alcohol resin
Catalog Number: D-1105.0005BA
Supplier: Bachem Americas


Description: Sequence: Z-Arg(Pmc)-OH · CHA
Catalog Number: C-3490.0005BA
Supplier: Bachem Americas


Description: Sequence: H-D-Val-Leu-Arg-pNA · 2 AcOH
Synonym(s): DVal-Leu-Arg-pNA
Catalog Number: L-1885.0050BA
Supplier: Bachem Americas


Description: Sequence: Fmoc-Gly-SASRIN™ resin (200-400 mesh)
Catalog Number: D-1345.0001BA
Supplier: Bachem Americas


Description: Sequence: Suc-Ala-Ala-Pro-Arg-pNA
Catalog Number: L-1720.0250BA
Supplier: Bachem Americas


Description: Sequence: Fmoc-Gly-OSu
Catalog Number: B-1335.0005BA
Supplier: Bachem Americas


Description: Sequence: Boc-Arg(Pbf)-OH
Catalog Number: A-3565.0005BA
Supplier: Bachem Americas


Description: Sequence: H-Leu-Gly-βNA
Catalog Number: K-1400.0250BA
Supplier: Bachem Americas


Description: Sequence: Fmoc-D-Arg(Pmc)-OH
Catalog Number: B-1680.0005BA
Supplier: Bachem Americas


Description: Sequence: Suc-Gly-Gly-Phe-pNA
Catalog Number: L-1415.0050BA
Supplier: Bachem Americas


Description: Sequence: H-Arg(Pbf)-OtBu · HCl
Catalog Number: E-3330.0005BA
Supplier: Bachem Americas


305 - 320 of 2,197